UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YOR124C

Length:

1272

Number of sequences:

5887

Description:

YOR124C UBP2 SGDID:S000005650, Chr XV from 558642-554824, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins; interacts with Rsp5p and is required for MVB sorting of membrane proteins; can cleave polyubiquitin and has isopeptidase activity"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
121	A6NNY8	438	UBP27_HUMAN Ubiquitin carboxyl-terminal hydro...	81	0.21	39.3	35	52
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
122	Q8CEG8	438	UBP27_MOUSE Ubiquitin carboxyl-terminal hydro...	81	0.21	39.3	35	52
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
123	B4HUI5	1059	UBP36_DROSE Ubiquitin carboxyl-terminal hydro...	49	0.22	39.7	41	55	GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
124	Q3LFD5	358	UBP41_HUMAN Putative ubiquitin carboxyl-termi...	47	0.22	39.3	40	57
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
125	B2GUZ1	961	UBP4_RAT Ubiquitin carboxyl-terminal hydrolas...	51	0.43	38.5	39	57	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0034394; P:protein localization at cell surface; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
126	E1C213	986	UBP37_CHICK Ubiquitin carboxyl-terminal hydro...	32	0.25	39.3	50	69
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0035871; P:protein K11-linked deubiquitination; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
127	P38187	747	UBP13_YEAST Ubiquitin carboxyl-terminal hydro...	92	0.54	38.1	30	45
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:SGD.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
128	O57429	357	UBP2_CHICK Ubiquitin carboxyl-terminal hydrol...	33	0.26	38.9	48	70	GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:Roslin.
									GO:0016579; P:protein deubiquitination; IDA:Roslin.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
129	P55824	2778	FAF_DROME Probable ubiquitin carboxyl-termina...	49	0.28	39.3	39	59	GO:0005737; C:cytoplasm; IDA:FlyBase.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:FlyBase.
									GO:0007349; P:cellularization; IMP:FlyBase.::GO:0009790; P:embryo development; IMP:FlyBase.::GO:0006897; P:endocytosis; NAS:FlyBase.::GO:0008354; P:germ cell migration; TAS:FlyBase.::GO:0008583; P:mystery cell differentiation; IMP:FlyBase.::GO:0045861; P:negative regulation of proteolysis; NAS:FlyBase.::GO:0007097; P:nuclear migration; IMP:FlyBase.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; IDA:FlyBase.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IGI:FlyBase.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
130	P50102	471	UBP8_YEAST Ubiquitin carboxyl-terminal hydrol...	48	0.29	38.9	35	52	GO:0071819; C:DUBm complex; IDA:SGD.::GO:0000124; C:SAGA complex; IDA:SGD.::GO:0046695; C:SLIK (SAGA-like) complex; IDA:SGD.
									GO:0032947; F:protein complex scaffold; IDA:SGD.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0016578; P:histone deubiquitination; IMP:SGD.::GO:0051568; P:histone H3-K4 methylation; IMP:SGD.::GO:0034729; P:histone H3-K79 methylation; IMP:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
131	B0Y4P5	767	CREB_ASPFC Probable ubiquitin carboxyl-termin...	66	0.43	38.5	35	50
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0045013; P:carbon catabolite repression of transcription; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
132	Q5RCD3	963	UBP4_PONAB Ubiquitin carboxyl-terminal hydrol...	73	0.84	37.7	30	47	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0034394; P:protein localization at cell surface; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
133	Q9LEW0	557	UBP22_ARATH Ubiquitin carboxyl-terminal hydro...	32	1.6	36.6	44	69
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
134	Q0CT11	768	CREB_ASPTN Probable ubiquitin carboxyl-termin...	66	0.37	38.9	35	52
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0045013; P:carbon catabolite repression of transcription; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
135	A1CIL1	760	CREB_ASPCL Probable ubiquitin carboxyl-termin...	66	0.58	38.1	35	50
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0045013; P:carbon catabolite repression of transcription; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
136	B2GUX4	565	UBP21_RAT Ubiquitin carboxyl-terminal hydrola...	63	1.3	37	37	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019784; F:NEDD8-specific protease activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
137	Q4WQI1	775	CREB_ASPFU Probable ubiquitin carboxyl-termin...	66	0.52	38.1	35	50
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0045013; P:carbon catabolite repression of transcription; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
138	Q9QZL6	566	UBP21_MOUSE Ubiquitin carboxyl-terminal hydro...	63	1.7	36.6	37	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IC:UniProtKB.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019784; F:NEDD8-specific protease activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016578; P:histone deubiquitination; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
139	Q9UK80	565	UBP21_HUMAN Ubiquitin carboxyl-terminal hydro...	63	1.5	36.6	37	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019784; F:NEDD8-specific protease activity; IDA:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
									GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
140	Q13107	963	UBP4_HUMAN Ubiquitin carboxyl-terminal hydrol...	73	0.92	37.7	30	47	GO:0005764; C:lysosome; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:UniProtKB.
									GO:0031685; F:adenosine receptor binding; IPI:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
									GO:0031397; P:negative regulation of protein ubiquitination; IMP:UniProtKB.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0034394; P:protein localization at cell surface; IDA:UniProtKB.::GO:0031647; P:regulation of protein stability; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
141	A6QR55	963	UBP4_BOVIN Ubiquitin carboxyl-terminal hydrol...	73	1.6	37	30	47	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0034394; P:protein localization at cell surface; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
142	A1CW53	761	CREB_NEOFI Probable ubiquitin carboxyl-termin...	66	0.41	38.5	35	50
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0045013; P:carbon catabolite repression of transcription; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
143	Q9WZ26	354	LEU3_THEMA 3-isopropylmalate dehydrogenase OS...	113	0.36	38.5	30	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
144	A4FUN7	371	UBP12_DANRE Ubiquitin carboxyl-terminal hydro...	45	0.41	38.1	38	49
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
145	C0HB46	372	UBP12_SALSA Ubiquitin carboxyl-terminal hydro...	45	0.48	38.1	38	49
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
146	Q0IIF7	494	UBP14_BOVIN Ubiquitin carboxyl-terminal hydro...	83	0.49	38.1	27	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0070628; F:proteasome binding; IDA:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
147	O74442	457	UBP16_SCHPO Probable ubiquitin carboxyl-termi...	35	0.65	37.7	43	69	GO:0005730; C:nucleolus; IDA:PomBase.
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
									GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
148	P54578	494	UBP14_HUMAN Ubiquitin carboxyl-terminal hydro...	83	0.57	38.1	27	43	GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
									GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0004866; F:endopeptidase inhibitor activity; IMP:UniProtKB.::GO:0070628; F:proteasome binding; IDA:UniProtKB.::GO:0008193; F:tRNA guanylyltransferase activity; TAS:ProtInc.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; TAS:ProtInc.
									GO:0050920; P:regulation of chemotaxis; IMP:UniProtKB.::GO:0061136; P:regulation of proteasomal protein catabolic process; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
149	P60051	493	UBP14_PANTR Ubiquitin carboxyl-terminal hydro...	83	0.59	38.1	27	43	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
150	Q9UUD6	350	UBP11_SCHPO Ubiquitin carboxyl-terminal hydro...	52	0.67	37.7	35	52	GO:0005739; C:mitochondrion; IDA:PomBase.
									GO:0005515; F:protein binding; IPI:PomBase.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
									GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
151	Q6P9L4	685	UBP49_MOUSE Ubiquitin carboxyl-terminal hydro...	102	0.7	37.7	29	45
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.

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