Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR124C
Length:
1272
Number of sequences:
5887
Description:
YOR124C UBP2 SGDID:S000005650, Chr XV from 558642-554824, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins; interacts with Rsp5p and is required for MVB sorting of membrane proteins; can cleave polyubiquitin and has isopeptidase activity"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q01476    1272   UBP2_YEAST Ubiquitin carboxyl-terminal hydrol...12720     2621     100     100GO:0005737; C:cytoplasm; IC:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.
GO:0016579; P:protein deubiquitination; IDA:SGD.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:SGD.
2O42726    1220   UBP2_KLULA Ubiquitin carboxyl-terminal hydrol...12260     1123     48     65
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
3Q9P3U0    1141   UBP2_SCHPO Probable ubiquitin carboxyl-termin...8578e-87     311     29     50GO:0005829; C:cytosol; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:PomBase.
4D3ZJ96    1083   UBP28_RAT Ubiquitin carboxyl-terminal hydrola...690.092     40.8     28     57GO:0005654; C:nucleoplasm; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0000077; P:DNA damage checkpoint; ISS:UniProtKB.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
5Q5I043    1051   UBP28_MOUSE Ubiquitin carboxyl-terminal hydro...690.089     40.8     26     57GO:0005654; C:nucleoplasm; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0000077; P:DNA damage checkpoint; ISS:UniProtKB.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
6Q5ZID5    1047   UBP28_CHICK Ubiquitin carboxyl-terminal hydro...1790.009     44.3     23     46GO:0005654; C:nucleoplasm; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0000077; P:DNA damage checkpoint; ISS:UniProtKB.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
7Q96RU2    1077   UBP28_HUMAN Ubiquitin carboxyl-terminal hydro...690.52     38.5     26     55GO:0005730; C:nucleolus; IDA:HPA.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.::GO:0043234; C:protein complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0008283; P:cell proliferation; IMP:UniProtKB.::GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0000077; P:DNA damage checkpoint; IMP:UniProtKB.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IDA:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
8P57080    1055   UBP25_MOUSE Ubiquitin carboxyl-terminal hydro...2070.049     41.6     24     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
9Q9UHP3    1055   UBP25_HUMAN Ubiquitin carboxyl-terminal hydro...2070.029     42.4     24     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032183; F:SUMO binding; IDA:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IMP:UniProtKB.
GO:0071108; P:protein K48-linked deubiquitination; IMP:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
10Q09931    1307   UBPY_CAEEL Probable ubiquitin carboxyl-termin...293.2     35.8     52     66
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
11Q8R5K2    909   UBP33_MOUSE Ubiquitin carboxyl-terminal hydro...310.28     39.3     48     71GO:0044297; C:cell body; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0007411; P:axon guidance; IMP:UniProtKB.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
12Q8TEY7    942   UBP33_HUMAN Ubiquitin carboxyl-terminal hydro...310.31     39.3     48     71GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0030891; C:VCB complex; TAS:UniProtKB.
GO:0004197; F:cysteine-type endopeptidase activity; IMP:UniProtKB.::GO:0001664; F:G-protein coupled receptor binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; TAS:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:UniProtKB.
13Q5REG5    914   UBP33_PONAB Ubiquitin carboxyl-terminal hydro...310.31     38.9     48     71GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
14A6QNM7    912   UBP33_BOVIN Ubiquitin carboxyl-terminal hydro...310.29     39.3     48     71GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
15Q24574    1556   UBPE_DROME Ubiquitin carboxyl-terminal hydrol...750.00004     52     36     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0031935; P:regulation of chromatin silencing; IMP:FlyBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
16Q28CN3    892   UBP33_XENTR Ubiquitin carboxyl-terminal hydro...310.15     40     52     68GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
17Q9WTV6    368   UBP18_MOUSE Ubl carboxyl-terminal hydrolase 1...1650.0001     49.7     30     42
GO:0019785; F:ISG15-specific protease activity; IMP:MGI.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0032020; P:ISG15-protein conjugation; IMP:MGI.::GO:0035634; P:response to stilbenoid; IEP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
18E1C1R4    1375   UBP47_CHICK Ubiquitin carboxyl-terminal hydro...2950.0002     49.3     22     38GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006284; P:base-excision repair; ISS:UniProtKB.::GO:0035520; P:monoubiquitinated protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
19Q949Y0    482   UBP6_ARATH Ubiquitin carboxyl-terminal hydrol...1600.047     41.6     24     44GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005516; F:calmodulin binding; IDA:TAIR.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IGI:TAIR.
GO:0016579; P:protein deubiquitination; TAS:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
20Q2LZB1    1059   UBP36_DROPS Ubiquitin carboxyl-terminal hydro...490.0005     48.1     49     61GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
21Q9UMW8    372   UBP18_HUMAN Ubl carboxyl-terminal hydrolase 1...690.0007     47.4     39     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:LIFEdb.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:ProtInc.
GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
22A1A5G2    1354   UBP47_XENTR Ubiquitin carboxyl-terminal hydro...560.001     47.4     38     59GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006284; P:base-excision repair; ISS:UniProtKB.::GO:0035520; P:monoubiquitinated protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
23A5PMR2    897   UBP33_DANRE Ubiquitin carboxyl-terminal hydro...370.092     40.8     46     65GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
24Q9FPS4    859   UBP23_ARATH Ubiquitin carboxyl-terminal hydro...690.001     47     33     54
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
25Q5U252    1350   UBP47_XENLA Ubiquitin carboxyl-terminal hydro...560.001     46.6     38     57GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006284; P:base-excision repair; ISS:UniProtKB.::GO:0035520; P:monoubiquitinated protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
26P50101    1230   UBP15_YEAST Ubiquitin carboxyl-terminal hydro...1231.8     36.6     25     48GO:0005737; C:cytoplasm; IDA:SGD.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.
GO:0016579; P:protein deubiquitination; IC:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
27Q96K76    1375   UBP47_HUMAN Ubiquitin carboxyl-terminal hydro...2950.002     46.6     22     38GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.::GO:0071987; F:WD40-repeat domain binding; IPI:UniProtKB.
GO:0006284; P:base-excision repair; IMP:UniProtKB.::GO:0034644; P:cellular response to UV; ISS:UniProtKB.::GO:0035520; P:monoubiquitinated protein deubiquitination; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.::GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.::GO:0042493; P:response to drug; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
28Q8LAM0    365   UBP4_ARATH Ubiquitin carboxyl-terminal hydrol...310.094     40.4     52     65GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
29Q8NFA0    1604   UBP32_HUMAN Ubiquitin carboxyl-terminal hydro...670.054     41.6     34     51GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
GO:0016579; P:protein deubiquitination; TAS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
30Q6A4J8    1103   UBP7_MOUSE Ubiquitin carboxyl-terminal hydrol...810.002     46.2     27     51GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
31Q5RE63    375   UBP18_PONAB Ubl carboxyl-terminal hydrolase 1...690.002     45.8     38     52
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
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