UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YOR090C

Length:

572

Number of sequences:

5887

Description:

YOR090C PTC5 SGDID:S000005616, Chr XV from 492841-491123, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial type 2C protein phosphatase (PP2C) involved in regulation of pyruvate dehydrogenase activity by dephosphorylating the serine 133 of the Pda1p subunit; acts in concert with kinases Pkp1p and Pkp2p and phosphatase Ptc6p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	Q12511	572	PP2C5_YEAST Protein phosphatase 2C homolog 5 ...	572	0	1176	100	100	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:SGD.
									GO:0043085; P:positive regulation of catalytic activity; IMP:SGD.::GO:0006470; P:protein dephosphorylation; IDA:SGD.
2	O14189	444	PP2C5_SCHPO Protein phosphatase 2C homolog C1...	422	1e-80	266	40	55	GO:0005739; C:mitochondrion; IDA:PomBase.
									GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; ISS:PomBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
									GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.]
3	Q9P2J9	529	PDP2_HUMAN [Pyruvate dehydrogenase [acetyl-tr...	454	2e-40	158	28	44	GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.]
4	O88484	530	PDP2_RAT [Pyruvate dehydrogenase [acetyl-tran...	508	2e-39	154	27	46	GO:0019910; C:mitochondrial pyruvate dehydrogenase (lipoamide) phosphatase complex; TAS:RGD.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; IDA:RGD.::GO:0000287; F:magnesium ion binding; IC:RGD.::GO:0004724; F:magnesium-dependent protein serine/threonine phosphatase activity; IDA:RGD.
									GO:0009758; P:carbohydrate utilization; TAS:RGD.::GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.]
5	P35816	538	PDP1_BOVIN [Pyruvate dehydrogenase [acetyl-tr...	453	4e-39	154	26	46	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; IEA:EC.::GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; NAS:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.]
6	Q3UV70	538	PDP1_MOUSE [Pyruvate dehydrogenase [acetyl-tr...	453	4e-39	154	26	46	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; IEA:EC.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.]
7	Q5RA52	537	PDP1_PONAB [Pyruvate dehydrogenase [acetyl-tr...	459	5e-39	153	26	45	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.]
8	Q9P0J1	537	PDP1_HUMAN [Pyruvate dehydrogenase [acetyl-tr...	459	6e-39	153	26	45	GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; IEA:EC.
									GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.]
9	O88483	538	PDP1_RAT [Pyruvate dehydrogenase [acetyl-tran...	453	2e-38	152	26	46	GO:0005759; C:mitochondrial matrix; TAS:RGD.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; IDA:RGD.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:RGD.::GO:0004724; F:magnesium-dependent protein serine/threonine phosphatase activity; IDA:RGD.::GO:0032403; F:protein complex binding; IMP:RGD.
									GO:0043085; P:positive regulation of catalytic activity; IC:RGD.::GO:0006470; P:protein dephosphorylation; IDA:RGD.]
10	Q94CL8	384	P2C48_ARATH Probable protein phosphatase 2C 4...	347	4e-21	99	29	46	GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
11	Q501F9	370	P2C67_ARATH Probable protein phosphatase 2C 6...	253	6e-21	98.2	31	51	GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
12	Q7XVF9	520	P2C39_ORYSJ Probable protein phosphatase 2C 3...	269	1e-19	95.9	28	45
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
13	Q9LHJ9	385	P2C38_ARATH Probable protein phosphatase 2C 3...	294	6e-19	92.4	28	46	GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
14	Q9LUS8	493	P2C40_ARATH Probable protein phosphatase 2C 4...	380	7e-19	93.6	24	40
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
15	Q0V7V2	384	P2C42_ARATH Probable protein phosphatase 2C 4...	307	5e-18	89.7	26	43	GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
16	A0DTY1	301	PP2C4_PARTE Probable protein phosphatase 2C 4...	255	1e-17	87.4	27	47	GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
17	Q5PNS9	400	P2C64_ARATH Probable protein phosphatase 2C 6...	352	1e-16	85.9	26	43	GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
18	Q9SD12	379	P2C46_ARATH Probable protein phosphatase 2C 4...	296	2e-16	84.7	28	45	GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
19	Q2QN36	392	P2C78_ORYSJ Probable protein phosphatase 2C 7...	297	2e-16	84.7	27	44	GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
20	Q84JD5	393	P2C68_ARATH Probable protein phosphatase 2C 6...	294	0.000000000000001	82.8	27	45	GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
21	P49444	300	PP2C1_PARTE Protein phosphatase 2C 1 OS=Param...	254	0.000000000000002	80.5	28	44	GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
22	A0BLX0	300	PP2C2_PARTE Probable protein phosphatase 2C 2...	252	0.000000000000004	79.7	27	44	GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
23	A0BQL0	300	PP2C3_PARTE Probable protein phosphatase 2C 3...	258	0.00000000000001	78.2	29	45	GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
24	Q7XUC5	388	P2C43_ORYSJ Probable protein phosphatase 2C 4...	257	0.00000000000002	79	28	44	GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
25	Q10S32	399	P2C28_ORYSJ Probable protein phosphatase 2C 2...	298	0.00000000000002	79	26	43	GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
26	Q7XCJ7	393	P2C72_ORYSJ Probable protein phosphatase 2C 7...	292	0.00000000000002	79	26	48	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
27	Q9LNW3	442	P2C03_ARATH Protein phosphatase 2C 3 OS=Arabi...	257	0.00000000000003	78.6	26	42	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005267; F:potassium channel activity; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
28	Q7XHN8	377	P2C61_ORYSJ Probable protein phosphatase 2C 6...	255	0.0000000000002	75.9	30	45	GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
29	Q6ZHC8	387	P2C25_ORYSJ Probable protein phosphatase 2C 2...	260	0.0000000000006	74.3	28	44	GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
30	O81760	380	P2C63_ARATH Probable protein phosphatase 2C 6...	267	0.0000000000007	73.9	27	43	GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.
31	Q6EN45	363	P2C13_ORYSJ Probable protein phosphatase 2C 1...	274	0.0000000000009	73.6	28	42	GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
									GO:0006470; P:protein dephosphorylation; IEA:InterPro.

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