Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR089C
Length:
210
Number of sequences:
5887
Description:
YOR089C VPS21 SGDID:S000005615, Chr XV from 490828-490196, Genome Release 64-1-1, reverse complement, Verified ORF, "Rab family GTPase required for endocytic transport and for sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
691P60953    191   CDC42_HUMAN Cell division control protein 42 ...1691e-17     81.6     30     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0000139; C:Golgi membrane; ISS:BHF-UCL.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0072686; C:mitotic spindle; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0051233; C:spindle midzone; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0019901; F:protein kinase binding; IDA:BHF-UCL.::GO:0031996; F:thioesterase binding; IPI:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0051683; P:establishment of Golgi localization; ISS:BHF-UCL.::GO:0007163; P:establishment or maintenance of cell polarity; TAS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:BHF-UCL.::GO:0030225; P:macrophage differentiation; TAS:UniProtKB.::GO:0042692; P:muscle cell differentiation; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0031333; P:negative regulation of protein complex assembly; IPI:UniProtKB.::GO:0072384; P:organelle transport along microtubule; ISS:BHF-UCL.::GO:0071777; P:positive regulation of cell cycle cytokinesis; IMP:UniProtKB.::GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.::GO:0031274; P:positive regulation of pseudopodium assembly; IDA:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; IDA:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.
692P60952    191   CDC42_CANFA Cell division control protein 42 ...1691e-17     81.6     30     49GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0072686; C:mitotic spindle; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
693Q2KJ93    191   CDC42_BOVIN Cell division control protein 42 ...1691e-17     81.6     30     49GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0072686; C:mitotic spindle; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
694Q9PSX7    193   RHOC_CHICK Rho-related GTP-binding protein Rh...1671e-17     81.6     30     51GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0043297; P:apical junction assembly; ISS:UniProtKB.::GO:0033205; P:cell cycle cytokinesis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
695Q90694    191   CDC42_CHICK Cell division control protein 42 ...1691e-17     81.6     30     49GO:0005912; C:adherens junction; ISS:AgBase.::GO:0005737; C:cytoplasm; ISS:AgBase.::GO:0030175; C:filopodium; ISS:AgBase.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0072686; C:mitotic spindle; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:AgBase.::GO:0051233; C:spindle midzone; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:AgBase.
GO:0046847; P:filopodium assembly; ISS:AgBase.::GO:0045185; P:maintenance of protein location; ISS:AgBase.::GO:0031333; P:negative regulation of protein complex assembly; ISS:AgBase.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:AgBase.::GO:0045860; P:positive regulation of protein kinase activity; ISS:AgBase.::GO:0031274; P:positive regulation of pseudopodium assembly; ISS:AgBase.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
696C4YKT4    288   RAS1_CANAW Ras-like protein 1 OS=Candida albi...1531e-17     82.8     31     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
697P61589    193   RHOA_RAT Transforming protein RhoA OS=Rattus ...1671e-17     81.6     30     50GO:0043296; C:apical junction complex; ISS:UniProtKB.::GO:0030424; C:axon; IDA:RGD.::GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005525; F:GTP binding; TAS:RGD.::GO:0003924; F:GTPase activity; NAS:RGD.::GO:0019904; F:protein domain specific binding; IPI:RGD.
GO:0030036; P:actin cytoskeleton organization; TAS:RGD.::GO:0043297; P:apical junction assembly; ISS:UniProtKB.::GO:0051927; P:negative regulation of calcium ion transport via voltage-gated calcium channel activity; IMP:RGD.::GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB cascade; IMP:RGD.::GO:0045665; P:negative regulation of neuron differentiation; IMP:RGD.::GO:0048812; P:neuron projection morphogenesis; IEP:RGD.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:RGD.::GO:0045785; P:positive regulation of cell adhesion; IEP:RGD.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IEP:RGD.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:RGD.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0045727; P:positive regulation of translation; IEP:RGD.::GO:0045907; P:positive regulation of vasoconstriction; IEP:RGD.::GO:0050773; P:regulation of dendrite development; IMP:RGD.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0042493; P:response to drug; IDA:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0031098; P:stress-activated protein kinase signaling cascade; IMP:RGD.
698Q9QUI0    193   RHOA_MOUSE Transforming protein RhoA OS=Mus m...1671e-17     81.6     30     50GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0032587; C:ruffle membrane; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:MGI.
GO:0030521; P:androgen receptor signaling pathway; IDA:MGI.::GO:0043297; P:apical junction assembly; IDA:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000902; P:cell morphogenesis; IGI:MGI.::GO:0007160; P:cell-matrix adhesion; IDA:MGI.::GO:0007229; P:integrin-mediated signaling pathway; TAS:MGI.::GO:0033144; P:negative regulation of intracellular steroid hormone receptor signaling pathway; IDA:MGI.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0043931; P:ossification involved in bone maturation; IMP:BHF-UCL.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0033688; P:regulation of osteoblast proliferation; IMP:BHF-UCL.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0007266; P:Rho protein signal transduction; TAS:MGI.::GO:0007519; P:skeletal muscle tissue development; IDA:MGI.::GO:0043149; P:stress fiber assembly; IDA:MGI.::GO:0061383; P:trabecula morphogenesis; IMP:BHF-UCL.
699P0CY32    290   RAS1_CANAX Ras-like protein 1 OS=Candida albi...1531e-17     82.8     31     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
700Q874R1    203   RHO4_SCHPO GTP-binding protein rho4 OS=Schizo...1791e-17     82     30     48GO:0000935; C:barrier septum; IDA:PomBase.::GO:0005938; C:cell cortex; IDA:PomBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IC:PomBase.::GO:0003924; F:GTPase activity; TAS:PomBase.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0031505; P:fungal-type cell wall organization; TAS:PomBase.::GO:0000226; P:microtubule cytoskeleton organization; IMP:PomBase.::GO:0030994; P:primary cell septum disassembly; TAS:PomBase.::GO:0032956; P:regulation of actin cytoskeleton organization; IMP:PomBase.::GO:0032955; P:regulation of barrier septum assembly; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IMP:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
701Q5REY6    193   RHOA_PONAB Transforming protein RhoA OS=Pongo...1671e-17     81.6     30     50GO:0043296; C:apical junction complex; ISS:UniProtKB.::GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0043297; P:apical junction assembly; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
702P61586    193   RHOA_HUMAN Transforming protein RhoA OS=Homo ...1671e-17     81.6     30     50GO:0043296; C:apical junction complex; IDA:UniProtKB.::GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:UniProtKB.::GO:0017022; F:myosin binding; IPI:UniProtKB.
GO:0043297; P:apical junction assembly; IMP:UniProtKB.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0050771; P:negative regulation of axonogenesis; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043931; P:ossification involved in bone maturation; ISS:BHF-UCL.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0050772; P:positive regulation of axonogenesis; TAS:Reactome.::GO:0071777; P:positive regulation of cell cycle cytokinesis; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEP:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; IMP:MGI.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; NAS:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; IDA:MGI.::GO:0030334; P:regulation of cell migration; IMP:UniProtKB.::GO:0033688; P:regulation of osteoblast proliferation; ISS:BHF-UCL.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007266; P:Rho protein signal transduction; TAS:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; IMP:BHF-UCL.::GO:0061383; P:trabecula morphogenesis; ISS:BHF-UCL.
703P61585    193   RHOA_BOVIN Transforming protein RhoA OS=Bos t...1671e-17     81.6     30     50GO:0043296; C:apical junction complex; ISS:UniProtKB.::GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0043297; P:apical junction assembly; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
704Q4R4R6    191   CDC42_MACFA Cell division control protein 42 ...1691e-17     81.6     30     49GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0072686; C:mitotic spindle; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
705P41914    223   RAN_TETPY GTP-binding nuclear protein Ran OS=...1681e-17     82     32     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
706Q23862    223   RACE_DICDI Rho-related protein racE OS=Dictyo...1721e-17     82     30     50GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0019953; P:sexual reproduction; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
707Q9C3Y4    193   RHOA_EMENI GTP-binding protein rhoA OS=194 / ...1681e-17     81.6     31     52GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
708Q6RUV5    192   RAC1_RAT Ras-related C3 botulinum toxin subst...1691e-17     81.3     30     49GO:0000139; C:Golgi membrane; IDA:RGD.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IDA:RGD.::GO:0003924; F:GTPase activity; IDA:RGD.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0017137; F:Rab GTPase binding; IPI:RGD.
GO:0007015; P:actin filament organization; IMP:RGD.::GO:0045453; P:bone resorption; IDA:RGD.::GO:0008283; P:cell proliferation; IMP:RGD.::GO:0002551; P:mast cell chemotaxis; IMP:RGD.::GO:0045740; P:positive regulation of DNA replication; IMP:RGD.::GO:0016601; P:Rac protein signal transduction; TAS:RGD.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.
709P63001    192   RAC1_MOUSE Ras-related C3 botulinum toxin sub...1691e-17     81.3     30     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0019897; C:extrinsic to plasma membrane; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0001891; C:phagocytic cup; IDA:UniProtKB.::GO:0032587; C:ruffle membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IDA:MGI.::GO:0030742; F:GTP-dependent protein binding; IPI:UniProtKB.::GO:0003924; F:GTPase activity; IDA:MGI.
GO:0048532; P:anatomical structure arrangement; IMP:MGI.::GO:0002093; P:auditory receptor cell morphogenesis; IMP:MGI.::GO:0007411; P:axon guidance; IMP:MGI.::GO:0045216; P:cell-cell junction organization; IMP:MGI.::GO:0021799; P:cerebral cortex radially oriented cell migration; IMP:MGI.::GO:0090103; P:cochlea morphogenesis; IMP:MGI.::GO:0007010; P:cytoskeleton organization; IDA:MGI.::GO:0048813; P:dendrite morphogenesis; IGI:MGI.::GO:0071542; P:dopaminergic neuron differentiation; IGI:MGI.::GO:0021831; P:embryonic olfactory bulb interneuron precursor migration; IMP:MGI.::GO:0043652; P:engulfment of apoptotic cell; IDA:BHF-UCL.::GO:0003382; P:epithelial cell morphogenesis; IMP:MGI.::GO:0006972; P:hyperosmotic response; IDA:MGI.::GO:0030032; P:lamellipodium assembly; IDA:MGI.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:MGI.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:MGI.::GO:0030334; P:regulation of cell migration; IMP:MGI.::GO:0097178; P:ruffle assembly; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI.::GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:MGI.::GO:0060071; P:Wnt receptor signaling pathway, planar cell polarity pathway; IGI:MGI.
710P63000    192   RAC1_HUMAN Ras-related C3 botulinum toxin sub...1691e-17     81.3     30     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; TAS:UniProtKB.::GO:0031996; F:thioesterase binding; IPI:UniProtKB.
GO:0030041; P:actin filament polymerization; TAS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0048870; P:cell motility; IDA:UniProtKB.::GO:0007160; P:cell-matrix adhesion; NAS:BHF-UCL.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0006954; P:inflammatory response; TAS:ProtInc.::GO:0030032; P:lamellipodium assembly; IMP:UniProtKB.::GO:0051668; P:localization within membrane; IMP:BHF-UCL.::GO:0032707; P:negative regulation of interleukin-23 production; IDA:BHF-UCL.::GO:0048261; P:negative regulation of receptor-mediated endocytosis; TAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0010592; P:positive regulation of lamellipodium assembly; IDA:MGI.::GO:0035025; P:positive regulation of Rho protein signal transduction; TAS:UniProtKB.::GO:0030334; P:regulation of cell migration; IMP:UniProtKB.::GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.::GO:0010310; P:regulation of hydrogen peroxide metabolic process; TAS:BHF-UCL.::GO:0060263; P:regulation of respiratory burst; IDA:BHF-UCL.::GO:0031529; P:ruffle organization; TAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
711P62999    192   RAC1_CANFA Ras-related C3 botulinum toxin sub...1691e-17     81.3     30     49GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; ISS:UniProtKB.
GO:0048870; P:cell motility; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
712P62998    192   RAC1_BOVIN Ras-related C3 botulinum toxin sub...1691e-17     81.3     30     49GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; ISS:UniProtKB.
GO:0030334; P:regulation of cell migration; ISS:UniProtKB.
713P34145    194   RAC1B_DICDI Rho-related protein rac1B OS=Dict...1691e-17     81.3     30     50GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; TAS:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0006897; P:endocytosis; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:dictyBase.::GO:0008360; P:regulation of cell shape; IMP:dictyBase.::GO:0019953; P:sexual reproduction; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
714O76321    199   RECG_ENTHI Rho-related protein racG OS=Entamo...1691e-17     81.6     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
715Q22038    192   RHO1_CAEEL Ras-like GTP-binding protein rhoA ...1671e-17     81.3     29     50GO:0005938; C:cell cortex; IDA:WormBase.::GO:0032154; C:cleavage furrow; IDA:WormBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IDA:WormBase.::GO:0003924; F:GTPase activity; IDA:WormBase.::GO:0019901; F:protein kinase binding; IPI:WormBase.
GO:0016477; P:cell migration; IMP:WormBase.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0030728; P:ovulation; IMP:WormBase.::GO:0014057; P:positive regulation of acetylcholine secretion; IMP:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0032970; P:regulation of actin filament-based process; IMP:WormBase.::GO:0030241; P:skeletal muscle myosin thick filament assembly; IMP:WormBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
716P62071    204   RRAS2_MOUSE Ras-related protein R-Ras2 OS=Mus...1461e-17     81.6     31     58GO:0005622; C:intracellular; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0030335; P:positive regulation of cell migration; IGI:MGI.::GO:0007265; P:Ras protein signal transduction; IDA:MGI.
717P62070    204   RRAS2_HUMAN Ras-related protein R-Ras2 OS=Hom...1461e-17     81.6     31     58GO:0005783; C:endoplasmic reticulum; NAS:ProtInc.::GO:0005886; C:plasma membrane; NAS:ProtInc.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.
718Q5R6S2    199   DIRA2_PONAB GTP-binding protein Di-Ras2 OS=Po...1622e-17     80.9     33     49GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
719C4YDI6    191   CDC42_CANAW Cell division control protein 42 ...1692e-17     80.9     30     51GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
720P0CY33    191   CDC42_CANAL Cell division control protein 42 ...1692e-17     80.9     30     51GO:0030428; C:cell septum; NAS:CGD.::GO:0005935; C:cellular bud neck; IDA:CGD.::GO:0005934; C:cellular bud tip; IDA:CGD.::GO:0031562; C:hyphal tip polarisome; IDA:CGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0031521; C:spitzenkorper; IDA:CGD.
GO:0005525; F:GTP binding; IDA:CGD.
GO:0007114; P:cell budding; IMP:CGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000920; P:cytokinetic cell separation; IMP:CGD.::GO:0030010; P:establishment of cell polarity; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0001558; P:regulation of cell growth; IMP:CGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
721P34144    194   RAC1A_DICDI Rho-related protein rac1A OS=Dict...1692e-17     80.9     29     50GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
GO:0030838; P:positive regulation of actin filament polymerization; IDA:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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