Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR089C
Length:
210
Number of sequences:
5887
Description:
YOR089C VPS21 SGDID:S000005615, Chr XV from 490828-490196, Genome Release 64-1-1, reverse complement, Verified ORF, "Rab family GTPase required for endocytic transport and for sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
661Q15669    191   RHOH_HUMAN Rho-related GTP-binding protein Rh...1701e-18     84.3     32     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:HPA.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0005095; F:GTPase inhibitor activity; NAS:UniProtKB.::GO:0019210; F:kinase inhibitor activity; IDA:UniProtKB.::GO:0017048; F:Rho GTPase binding; NAS:UniProtKB.
GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0030217; P:T cell differentiation; NAS:UniProtKB.
662Q9VUN3    217   RANL_DROME GTP-binding nuclear protein Ran-li...1631e-18     84.7     27     51GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
663P01122    192   RHO_APLCA Ras-like GTP-binding protein RHO OS...1671e-18     84.3     31     50GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
664Q54FK5    216   RABN1_DICDI Ras-related protein RabN1 OS=Dict...1722e-18     84.3     28     52GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
665P19073    191   CDC42_YEAST Cell division control protein 42 ...1692e-18     84     30     50GO:0005935; C:cellular bud neck; TAS:SGD.::GO:0005934; C:cellular bud tip; TAS:SGD.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.::GO:0005625; C:soluble fraction; IDA:SGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; TAS:SGD.
GO:0007118; P:budding cell apical bud growth; IMP:SGD.::GO:0007119; P:budding cell isotropic bud growth; IMP:SGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IGI:SGD.::GO:0045921; P:positive regulation of exocytosis; IPI:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0007096; P:regulation of exit from mitosis; IMP:SGD.::GO:0031384; P:regulation of initiation of mating projection growth; IMP:SGD.::GO:0032889; P:regulation of vacuole fusion, non-autophagic; IMP:SGD.::GO:0007266; P:Rho protein signal transduction; TAS:SGD.
666Q9D3G9    191   RHOH_MOUSE Rho-related GTP-binding protein Rh...1932e-18     84     30     51GO:0001772; C:immunological synapse; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0045576; P:mast cell activation; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0030217; P:T cell differentiation; IDA:UniProtKB.
667Q86L51    205   RAPB_DICDI Ras-related protein rapB OS=Dictyo...1882e-18     84     28     55GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
668Q9GPQ8    196   RACL_DICDI Rho-related protein racL OS=Dictyo...1682e-18     84     30     52GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0019953; P:sexual reproduction; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
669P06781    192   RHO2_YEAST GTP-binding protein RHO2 OS=Saccha...1722e-18     84     33     49GO:0005622; C:intracellular; TAS:SGD.::GO:0005624; C:membrane fraction; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0004871; F:signal transducer activity; TAS:SGD.
GO:0007015; P:actin filament organization; TAS:SGD.::GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0031505; P:fungal-type cell wall organization; TAS:SGD.::GO:0007017; P:microtubule-based process; TAS:SGD.::GO:0007264; P:small GTPase mediated signal transduction; TAS:SGD.
670Q2HJG3    191   RHOH_BOVIN Rho-related GTP-binding protein Rh...1702e-18     83.6     32     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
671P48148    192   RHO1_DROME Ras-like GTP-binding protein Rho1 ...1672e-18     83.6     31     50GO:0005938; C:cell cortex; IDA:FlyBase.::GO:0070451; C:cell hair; IDA:FlyBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:FlyBase.::GO:0019900; F:kinase binding; IPI:FlyBase.
GO:0051017; P:actin filament bundle assembly; IMP:FlyBase.::GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0035147; P:branch fusion, open tracheal system; TAS:FlyBase.::GO:0090254; P:cell elongation involved in imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007349; P:cellularization; IMP:FlyBase.::GO:0000910; P:cytokinesis; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; TAS:FlyBase.::GO:0070593; P:dendrite self-avoidance; IGI:FlyBase.::GO:0007368; P:determination of left/right symmetry; IMP:FlyBase.::GO:0046663; P:dorsal closure, leading edge cell differentiation; IMP:FlyBase.::GO:0007395; P:dorsal closure, spreading of leading edge cells; IMP:FlyBase.::GO:0006897; P:endocytosis; IMP:FlyBase.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IGI:FlyBase.::GO:0001737; P:establishment of imaginal disc-derived wing hair orientation; TAS:FlyBase.::GO:0045184; P:establishment of protein localization; IMP:FlyBase.::GO:0008354; P:germ cell migration; TAS:FlyBase.::GO:0007377; P:germ-band extension; IMP:FlyBase.::GO:0008347; P:glial cell migration; IMP:FlyBase.::GO:0035099; P:hemocyte migration; IMP:FlyBase.::GO:0007254; P:JNK cascade; NAS:FlyBase.::GO:0035149; P:lumen formation, open tracheal system; IMP:FlyBase.::GO:0045199; P:maintenance of epithelial cell apical/basal polarity; IMP:FlyBase.::GO:0035006; P:melanization defense response; IMP:FlyBase.::GO:0008045; P:motor axon guidance; IMP:FlyBase.::GO:0007405; P:neuroblast proliferation; IMP:FlyBase.::GO:0016318; P:ommatidial rotation; NAS:FlyBase.::GO:0007422; P:peripheral nervous system development; IMP:FlyBase.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0007374; P:posterior midgut invagination; IMP:FlyBase.::GO:0030589; P:pseudocleavage involved in syncytial blastoderm formation; IMP:FlyBase.::GO:0050770; P:regulation of axonogenesis; IGI:FlyBase.::GO:0051493; P:regulation of cytoskeleton organization; IDA:FlyBase.::GO:0016476; P:regulation of embryonic cell shape; IMP:FlyBase.::GO:0035298; P:regulation of Malpighian tubule size; IMP:FlyBase.::GO:0035159; P:regulation of tube length, open tracheal system; IMP:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0035277; P:spiracle morphogenesis, open tracheal system; IMP:FlyBase.::GO:0007370; P:ventral furrow formation; IMP:FlyBase.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; NAS:FlyBase.::GO:0042060; P:wound healing; IMP:FlyBase.
672Q68Y52    214   RAC2_ORYSJ Rac-like GTP-binding protein 2 OS=...1732e-18     84     29     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
673Q8J212    208   RHO1_KLULA GTP-binding protein Rho1 OS=1267 /...1682e-18     84     30     53GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
674Q5RCK9    193   RHOC_PONAB Rho-related GTP-binding protein Rh...1672e-18     83.6     31     51GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0043297; P:apical junction assembly; ISS:UniProtKB.::GO:0033205; P:cell cycle cytokinesis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
675Q62159    193   RHOC_MOUSE Rho-related GTP-binding protein Rh...1672e-18     83.6     31     51GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0043297; P:apical junction assembly; IDA:UniProtKB.::GO:0033205; P:cell cycle cytokinesis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
676P08134    193   RHOC_HUMAN Rho-related GTP-binding protein Rh...1672e-18     83.6     31     51GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.
GO:0043297; P:apical junction assembly; IDA:UniProtKB.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0033205; P:cell cycle cytokinesis; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
677Q1RMJ6    193   RHOC_BOVIN Rho-related GTP-binding protein Rh...1672e-18     83.6     31     51GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0043297; P:apical junction assembly; ISS:UniProtKB.::GO:0033205; P:cell cycle cytokinesis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
678Q09914    202   RHO1_SCHPO GTP-binding protein rho1 OS=Schizo...1682e-18     83.6     32     52GO:0000935; C:barrier septum; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0031234; C:extrinsic to internal side of plasma membrane; NAS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0030427; C:site of polarized growth; TAS:PomBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:PomBase.::GO:0060583; P:regulation of actin cortical patch localization; IGI:PomBase.::GO:0032956; P:regulation of actin cytoskeleton organization; IMP:PomBase.::GO:0032949; P:regulation of alpha-glucan biosynthetic process; IMP:PomBase.::GO:0032955; P:regulation of barrier septum assembly; IMP:PomBase.::GO:0090334; P:regulation of cell wall (1->3)-beta-D-glucan biosynthetic process; TAS:PomBase.::GO:0030100; P:regulation of endocytosis; ISS:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase.::GO:0007266; P:Rho protein signal transduction; TAS:PomBase.
679Q9GPS0    201   RACG_DICDI Rho-related protein racG OS=Dictyo...1693e-18     83.2     30     53GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0032009; C:early phagosome; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0046847; P:filopodium assembly; IMP:dictyBase.::GO:0006909; P:phagocytosis; IDA:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:dictyBase.::GO:0032314; P:regulation of Rac GTPase activity; IMP:dictyBase.::GO:0019953; P:sexual reproduction; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
680Q8VHP8    278   RB40B_MOUSE Ras-related protein Rab-40B OS=Mu...1724e-18     84     28     49GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
681Q24814    196   RACA_ENTHI Rho-related protein racA OS=Entamo...1694e-18     83.2     29     50GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
682P38544    215   RAN_ONCVO GTP-binding nuclear protein Ran OS=...1564e-18     83.2     30     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
683Q95KD9    199   DIRA2_MACFA GTP-binding protein Di-Ras2 OS=Ma...1625e-18     82.8     33     49GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
684Q9SSX0    214   RAC1_ORYSJ Rac-like GTP-binding protein 1 OS=...1945e-18     83.2     27     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
685Q96HU8    199   DIRA2_HUMAN GTP-binding protein Di-Ras2 OS=Ho...1625e-18     82.8     33     49GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
686Q5PR73    199   DIRA2_MOUSE GTP-binding protein Di-Ras2 OS=Mu...1627e-18     82.4     33     49GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
687Q55EF0    218   RABT2_DICDI Ras-related protein RabT2 OS=Dict...1611e-17     82.4     31     53GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
688Q8CFN2    191   CDC42_RAT Cell division control protein 42 ho...1691e-17     81.6     30     49GO:0000139; C:Golgi membrane; IDA:BHF-UCL.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0072686; C:mitotic spindle; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0030141; C:secretory granule; IDA:UniProtKB.::GO:0051233; C:spindle midzone; ISS:UniProtKB.
GO:0005525; F:GTP binding; TAS:UniProtKB.::GO:0003924; F:GTPase activity; TAS:RGD.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:RGD.
GO:0090135; P:actin filament branching; IMP:RGD.::GO:0030010; P:establishment of cell polarity; TAS:RGD.::GO:0051683; P:establishment of Golgi localization; IMP:BHF-UCL.::GO:0007030; P:Golgi organization; IMP:BHF-UCL.::GO:0072384; P:organelle transport along microtubule; IMP:BHF-UCL.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0045740; P:positive regulation of DNA replication; IMP:RGD.::GO:0090316; P:positive regulation of intracellular protein transport; IMP:RGD.::GO:0046330; P:positive regulation of JNK cascade; IDA:RGD.::GO:0048554; P:positive regulation of metalloenzyme activity; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0051835; P:positive regulation of synapse structural plasticity; IMP:RGD.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0017157; P:regulation of exocytosis; TAS:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; TAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0002040; P:sprouting angiogenesis; IMP:RGD.::GO:0060661; P:submandibular salivary gland formation; IEP:RGD.
689Q007T2    191   CDC42_PIG Cell division control protein 42 ho...1691e-17     81.6     30     49GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0072686; C:mitotic spindle; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
690P60766    191   CDC42_MOUSE Cell division control protein 42 ...1691e-17     81.6     30     49GO:0045177; C:apical part of cell; IDA:MGI.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0072686; C:mitotic spindle; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; ISS:UniProtKB.
GO:0005525; F:GTP binding; IDA:MGI.::GO:0030742; F:GTP-dependent protein binding; IPI:UniProtKB.::GO:0003924; F:GTPase activity; IDA:MGI.
GO:0051017; P:actin filament bundle assembly; IMP:MGI.::GO:0034332; P:adherens junction organization; IMP:MGI.::GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:MGI.::GO:0034613; P:cellular protein localization; IMP:MGI.::GO:0016197; P:endosome transport; TAS:UniProtKB.::GO:0090136; P:epithelial cell-cell adhesion; IMP:MGI.::GO:0060684; P:epithelial-mesenchymal cell signaling; IMP:MGI.::GO:0035088; P:establishment or maintenance of apical/basal cell polarity; IMP:MGI.::GO:0046847; P:filopodium assembly; IDA:MGI.::GO:0031069; P:hair follicle morphogenesis; IMP:MGI.::GO:0060789; P:hair follicle placode formation; IMP:MGI.::GO:0031424; P:keratinization; IMP:MGI.::GO:0003334; P:keratinocyte development; IMP:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0010629; P:negative regulation of gene expression; IMP:MGI.::GO:0048664; P:neuron fate determination; IMP:MGI.::GO:0007097; P:nuclear migration; IMP:MGI.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0010628; P:positive regulation of gene expression; IMP:MGI.::GO:0071338; P:positive regulation of hair follicle cell proliferation; IMP:MGI.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IMP:MGI.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:MGI.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.::GO:0007088; P:regulation of mitosis; IMP:MGI.::GO:0042176; P:regulation of protein catabolic process; IMP:MGI.::GO:0043497; P:regulation of protein heterodimerization activity; IDA:MGI.::GO:0045859; P:regulation of protein kinase activity; IMP:MGI.::GO:0031647; P:regulation of protein stability; IMP:MGI.::GO:0007266; P:Rho protein signal transduction; TAS:MGI.
691P60953    191   CDC42_HUMAN Cell division control protein 42 ...1691e-17     81.6     30     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0000139; C:Golgi membrane; ISS:BHF-UCL.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0072686; C:mitotic spindle; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0051233; C:spindle midzone; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0019901; F:protein kinase binding; IDA:BHF-UCL.::GO:0031996; F:thioesterase binding; IPI:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0051683; P:establishment of Golgi localization; ISS:BHF-UCL.::GO:0007163; P:establishment or maintenance of cell polarity; TAS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:BHF-UCL.::GO:0030225; P:macrophage differentiation; TAS:UniProtKB.::GO:0042692; P:muscle cell differentiation; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0031333; P:negative regulation of protein complex assembly; IPI:UniProtKB.::GO:0072384; P:organelle transport along microtubule; ISS:BHF-UCL.::GO:0071777; P:positive regulation of cell cycle cytokinesis; IMP:UniProtKB.::GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.::GO:0031274; P:positive regulation of pseudopodium assembly; IDA:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; IDA:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.
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