Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR089C
Length:
210
Number of sequences:
5887
Description:
YOR089C VPS21 SGDID:S000005615, Chr XV from 490828-490196, Genome Release 64-1-1, reverse complement, Verified ORF, "Rab family GTPase required for endocytic transport and for sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
541P03967    187   RASD_DICDI Ras-like protein rasD OS=Dictyoste...1843e-21     91.3     32     57GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:dictyBase.::GO:0005515; F:protein binding; IPI:dictyBase.
GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0000910; P:cytokinesis; IGI:dictyBase.::GO:0007275; P:multicellular organismal development; IMP:dictyBase.::GO:0042331; P:phototaxis; IMP:dictyBase.::GO:0007265; P:Ras protein signal transduction; ISS:dictyBase.::GO:0043052; P:thermotaxis; IMP:dictyBase.
542Q40220    196   RAC2_LOTJA Rac-like GTP-binding protein RAC2 ...1663e-21     91.7     33     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
543P06780    209   RHO1_YEAST GTP-binding protein RHO1 OS=Saccha...1683e-21     92     32     55GO:0000148; C:1,3-beta-D-glucan synthase complex; IDA:SGD.::GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; TAS:SGD.
GO:0031532; P:actin cytoskeleton reorganization; IPI:SGD.::GO:0007117; P:budding cell bud growth; IMP:SGD.::GO:0045807; P:positive regulation of endocytosis; IMP:SGD.::GO:0090037; P:positive regulation of protein kinase C signaling cascade; IMP:SGD.::GO:0008361; P:regulation of cell size; IMP:SGD.::GO:0060178; P:regulation of exocyst localization; IMP:SGD.::GO:0070610; P:regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process; IMP:SGD.::GO:0060237; P:regulation of fungal-type cell wall organization; IMP:SGD.::GO:0032889; P:regulation of vacuole fusion, non-autophagic; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IDA:SGD.
544Q56JV3    184   RHEB_BOVIN GTP-binding protein Rheb OS=Bos ta...1803e-21     91.3     36     53GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0032008; P:positive regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
545Q6Z808    214   RAC3_ORYSJ Rac-like GTP-binding protein 3 OS=...1663e-21     92     33     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
546Q15382    184   RHEB_HUMAN GTP-binding protein Rheb OS=Homo s...1834e-21     91.3     36     55GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007050; P:cell cycle arrest; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0032008; P:positive regulation of TOR signaling cascade; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
547O93856    209   RAS_LACBI Ras-like protein OS=bicolor). GN= ...1904e-21     91.7     29     52GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
548Q62639    184   RHEB_RAT GTP-binding protein Rheb OS=Rattus n...1804e-21     90.9     36     53GO:0030425; C:dendrite; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; IDA:RGD.::GO:0005525; F:GTP binding; IDA:RGD.::GO:0003924; F:GTPase activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:RGD.
GO:0032008; P:positive regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0048168; P:regulation of neuronal synaptic plasticity; NAS:RGD.::GO:0007264; P:small GTPase mediated signal transduction; IDA:RGD.
549Q9YH38    188   RASK_CYPCA GTPase KRas OS=Cyprinus carpio (Co...1685e-21     90.9     33     57GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
550Q38902    197   RAC1_ARATH Rac-like GTP-binding protein ARAC1...1665e-21     90.9     33     52GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0009524; C:phragmoplast; IDA:TAIR.::GO:0005819; C:spindle; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; TAS:TAIR.::GO:0009734; P:auxin mediated signaling pathway; IMP:TAIR.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
551Q38937    196   RAC5_ARATH Rac-like GTP-binding protein ARAC5...1666e-21     90.9     33     54GO:0005730; C:nucleolus; IDA:TAIR.::GO:0009524; C:phragmoplast; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
552Q921J2    184   RHEB_MOUSE GTP-binding protein Rheb OS=Mus mu...1826e-21     90.9     35     53GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IDA:MGI.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0032008; P:positive regulation of TOR signaling cascade; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
553Q38919    195   RAC4_ARATH Rac-like GTP-binding protein ARAC4...1666e-21     90.9     33     54GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0000226; P:microtubule cytoskeleton organization; IMP:TAIR.::GO:0009860; P:pollen tube growth; IMP:TAIR.::GO:0010119; P:regulation of stomatal movement; IMP:TAIR.::GO:0009416; P:response to light stimulus; IDA:TAIR.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
554P79800    188   RASK_MELGA GTPase KRas OS=Meleagris gallopavo...1686e-21     90.5     33     57GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
555Q5R988    183   RAP2A_PONAB Ras-related protein Rap-2a OS=Pon...1537e-21     90.5     36     56GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0034613; P:cellular protein localization; ISS:UniProtKB.::GO:0031954; P:positive regulation of protein autophosphorylation; ISS:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.::GO:0048814; P:regulation of dendrite morphogenesis; ISS:UniProtKB.::GO:0046328; P:regulation of JNK cascade; ISS:UniProtKB.
556Q80ZJ1    183   RAP2A_MOUSE Ras-related protein Rap-2a OS=Mus...1537e-21     90.5     36     56GO:0005829; C:cytosol; IDA:MGI.::GO:0055038; C:recycling endosome membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0034613; P:cellular protein localization; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:MGI.::GO:0031954; P:positive regulation of protein autophosphorylation; IDA:MGI.::GO:0032486; P:Rap protein signal transduction; IDA:UniProtKB.::GO:0048814; P:regulation of dendrite morphogenesis; ISS:UniProtKB.::GO:0046328; P:regulation of JNK cascade; ISS:UniProtKB.
557Q38912    198   RAC3_ARATH Rac-like GTP-binding protein ARAC3...1669e-21     90.5     33     54GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0030427; C:site of polarized growth; IDA:TAIR.::GO:0005819; C:spindle; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:TAIR.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
558P05774    183   RAS_CARAU Ras-like protein OS=Carassius aurat...1689e-21     90.1     33     56GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
559Q6ZHA3    197   RAC6_ORYSJ Rac-like GTP-binding protein 6 OS=...1661e-20     90.5     33     54
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
560P08644    189   RASK_RAT GTPase KRas OS=Rattus norvegicus (Ra...1681e-20     90.1     33     57GO:0045121; C:membrane raft; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0019003; F:GDP binding; IDA:RGD.::GO:0019002; F:GMP binding; IDA:RGD.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0030275; F:LRR domain binding; IDA:RGD.
GO:0019221; P:cytokine-mediated signaling pathway; IMP:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IMP:RGD.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:RGD.::GO:0051000; P:positive regulation of nitric-oxide synthase activity; IMP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0051385; P:response to mineralocorticoid stimulus; IEP:RGD.::GO:0035176; P:social behavior; IEP:RGD.
561P32883    189   RASK_MOUSE GTPase KRas OS=Mus musculus (Mouse...1681e-20     90.1     33     57GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IGI:MGI.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030036; P:actin cytoskeleton organization; IGI:MGI.::GO:0008284; P:positive regulation of cell proliferation; IGI:MGI.::GO:0035022; P:positive regulation of Rac protein signal transduction; IGI:MGI.::GO:0007265; P:Ras protein signal transduction; IGI:MGI.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IGI:MGI.::GO:0032228; P:regulation of synaptic transmission, GABAergic; IGI:MGI.::GO:0051146; P:striated muscle cell differentiation; IGI:MGI.::GO:0008542; P:visual learning; IGI:MGI.
562Q9VZ23    216   RAN_DROME GTP-binding nuclear protein Ran OS=...1681e-20     90.5     30     53GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0072686; C:mitotic spindle; IDA:FlyBase.::GO:0005880; C:nuclear microtubule; IDA:UniProtKB.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; TAS:UniProtKB.::GO:0000212; P:meiotic spindle organization; IMP:FlyBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
563Q8TAI7    183   REBL1_HUMAN GTPase RhebL1 OS=Homo sapiens (Hu...1821e-20     89.7     34     53GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0031929; P:TOR signaling cascade; IMP:UniProtKB.
564P97348    210   RHOD_MOUSE Rho-related GTP-binding protein Rh...1691e-20     90.1     31     51GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IDA:MGI.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
565Q5EFX7    188   RASK_KRYMA GTPase KRas OS=Kryptolebias marmor...1681e-20     89.7     33     57GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
566P61227    183   RAP2B_RAT Ras-related protein Rap-2b OS=Rattu...1531e-20     89.7     36     57GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.::GO:0061097; P:regulation of protein tyrosine kinase activity; ISS:UniProtKB.
567P61226    183   RAP2B_MOUSE Ras-related protein Rap-2b OS=Mus...1531e-20     89.7     36     57GO:0005829; C:cytosol; IDA:MGI.::GO:0055038; C:recycling endosome membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0019904; F:protein domain specific binding; IPI:MGI.
GO:0030336; P:negative regulation of cell migration; IDA:MGI.::GO:0031954; P:positive regulation of protein autophosphorylation; IDA:MGI.::GO:0032486; P:Rap protein signal transduction; IDA:UniProtKB.::GO:0061097; P:regulation of protein tyrosine kinase activity; IDA:UniProtKB.
568P61225    183   RAP2B_HUMAN Ras-related protein Rap-2b OS=Hom...1531e-20     89.7     36     57GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.::GO:0061097; P:regulation of protein tyrosine kinase activity; ISS:UniProtKB.
569Q06AU2    183   RAP2A_PIG Ras-related protein Rap-2a OS=Sus s...1531e-20     89.7     36     57GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0034613; P:cellular protein localization; ISS:UniProtKB.::GO:0031954; P:positive regulation of protein autophosphorylation; ISS:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.::GO:0048814; P:regulation of dendrite morphogenesis; ISS:UniProtKB.::GO:0046328; P:regulation of JNK cascade; ISS:UniProtKB.
570P01116    189   RASK_HUMAN GTPase KRas OS=Homo sapiens (Human...1681e-20     89.7     33     56GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0000165; P:MAPK cascade; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
571Q13637    225   RAB32_HUMAN Ras-related protein Rab-32 OS=Hom...1701e-20     90.5     31     54GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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