Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR089C
Length:
210
Number of sequences:
5887
Description:
YOR089C VPS21 SGDID:S000005615, Chr XV from 490828-490196, Genome Release 64-1-1, reverse complement, Verified ORF, "Rab family GTPase required for endocytic transport and for sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
391Q92963    219   RIT1_HUMAN GTP-binding protein Rit1 OS=Homo s...1702e-26     106     36     57GO:0005886; C:plasma membrane; TAS:ProtInc.
GO:0005516; F:calmodulin binding; TAS:ProtInc.::GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
392Q8VEA8    199   RAB7B_MOUSE Ras-related protein Rab-7b OS=Mus...1632e-26     105     34     59GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005770; C:late endosome; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0034499; P:late endosome to Golgi transport; ISS:UniProtKB.::GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; IMP:UniProtKB.::GO:0034164; P:negative regulation of toll-like receptor 9 signaling pathway; IMP:UniProtKB.::GO:0032755; P:positive regulation of interleukin-6 production; ISS:UniProtKB.::GO:0045654; P:positive regulation of megakaryocyte differentiation; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
393P22124    206   RAL_DISOM Ras-related protein O-RAL OS=Discop...1922e-26     105     33     59GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
394Q8BHH2    201   RAB9B_MOUSE Ras-related protein Rab-9B OS=Mus...2105e-26     104     35     50GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
395Q9NP90    201   RAB9B_HUMAN Ras-related protein Rab-9B OS=Hom...2106e-26     104     35     50GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006895; P:Golgi to endosome transport; NAS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
396Q5R4W9    201   RAB9B_PONAB Ras-related protein Rab-9B OS=Pon...2106e-26     104     35     50GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
397Q96AH8    199   RAB7B_HUMAN Ras-related protein Rab-7b OS=Hom...1607e-26     104     33     58GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005770; C:late endosome; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0034499; P:late endosome to Golgi transport; IMP:UniProtKB.::GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; ISS:UniProtKB.::GO:0034164; P:negative regulation of toll-like receptor 9 signaling pathway; ISS:UniProtKB.::GO:0032755; P:positive regulation of interleukin-6 production; IMP:UniProtKB.::GO:0045654; P:positive regulation of megakaryocyte differentiation; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
398Q5R7A4    203   RAB7L_PONAB Ras-related protein Rab-7L1 OS=Po...1848e-26     104     29     60GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
399O14966    203   RAB7L_HUMAN Ras-related protein Rab-7L1 OS=Ho...1848e-26     104     29     60GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
400Q08DE8    200   RAB7B_BOVIN Ras-related protein Rab-7b OS=Bos...1609e-26     103     33     59GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0034499; P:late endosome to Golgi transport; ISS:UniProtKB.::GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; ISS:UniProtKB.::GO:0034164; P:negative regulation of toll-like receptor 9 signaling pathway; ISS:UniProtKB.::GO:0032755; P:positive regulation of interleukin-6 production; ISS:UniProtKB.::GO:0045654; P:positive regulation of megakaryocyte differentiation; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
401P08645    184   RAS3_DROME Ras-like protein 3 OS=Drosophila m...1689e-26     103     38     58GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0007391; P:dorsal closure; IMP:FlyBase.::GO:0030718; P:germ-line stem cell maintenance; IGI:FlyBase.::GO:0035099; P:hemocyte migration; IMP:FlyBase.::GO:0030713; P:ovarian follicle cell stalk formation; TAS:FlyBase.::GO:0016476; P:regulation of embryonic cell shape; IMP:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006930; P:substrate-dependent cell migration, cell extension; IMP:FlyBase.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
402Q5RDE5    273   DJC27_PONAB DnaJ homolog subfamily C member 2...1623e-25     103     35     54
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
403A5D7F5    273   DJC27_BOVIN DnaJ homolog subfamily C member 2...1623e-25     103     35     54
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
404Q9YH37    184   RAP1B_CYPCA Ras-related protein Rap-1b OS=Cyp...1734e-25     102     36     57GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
405P01117    189   RASK_MSVKI GTPase KRas OS=Kirsten murine sarc...1684e-25     102     33     57GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
406Q9NZQ0    273   DJC27_HUMAN DnaJ homolog subfamily C member 2...1624e-25     103     35     54
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
407Q7Z6P3    723   RAB44_HUMAN Ras-related protein Rab-44 OS=Hom...1515e-25     107     35     58GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
408Q7ZYF1    273   DJ27A_XENLA DnaJ homolog subfamily C member 2...1625e-25     103     33     54
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
409Q63481    204   RAB7L_RAT Ras-related protein Rab-7L1 OS=Ratt...1846e-25     102     29     60GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; TAS:RGD.::GO:0003924; F:GTPase activity; TAS:RGD.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
410Q5RDM6    184   RAP1B_PONAB Ras-related protein Rap-1b OS=Pon...1737e-25     101     36     57GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.
411A5A6J7    184   RAP1B_PANTR Ras-related protein Rap-1b OS=Pan...1737e-25     101     36     57GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.
412Q99JI6    184   RAP1B_MOUSE Ras-related protein Rap-1b OS=Mus...1737e-25     101     36     57GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.
GO:0008283; P:cell proliferation; IPI:MGI.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI.
413Q4R9D4    184   RAP1B_MACFA Ras-related protein Rap-1b OS=Mac...1737e-25     101     36     57GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
414P61224    184   RAP1B_HUMAN Ras-related protein Rap-1b OS=Hom...1737e-25     101     36     57GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005811; C:lipid particle; IDA:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0019003; F:GDP binding; IDA:UniProtKB.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:2000114; P:regulation of establishment of cell polarity; IMP:UniProtKB.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
415Q5ZHX1    184   RAP1B_CHICK Ras-related protein Rap-1b OS=Gal...1737e-25     101     36     57GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
416P61223    184   RAP1B_BOVIN Ras-related protein Rap-1b OS=Bos...1737e-25     101     36     57GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.
417Q62636    184   RAP1B_RAT Ras-related protein Rap-1b OS=Rattu...1737e-25     101     36     57GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.
418Q6IMM1    273   DJC27_CHICK DnaJ homolog subfamily C member 2...1627e-25     103     33     54
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
419Q5M7D1    276   DJ27B_XENLA DnaJ homolog subfamily C member 2...1657e-25     103     33     54
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
420P62836    184   RAP1A_RAT Ras-related protein Rap-1A OS=Rattu...1767e-25     101     36     57GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
421P62835    184   RAP1A_MOUSE Ras-related protein Rap-1A OS=Mus...1767e-25     101     36     57GO:0032045; C:guanyl-nucleotide exchange factor complex; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:MGI.::GO:0017016; F:Ras GTPase binding; IPI:MGI.
GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI.
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