UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YOR089C

Length:

210

Number of sequences:

5887

Description:

YOR089C VPS21 SGDID:S000005615, Chr XV from 490828-490196, Genome Release 64-1-1, reverse complement, Verified ORF, "Rab family GTPase required for endocytic transport and for sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	P35285	194	RB22A_MOUSE Ras-related protein Rab-22A OS=Mu...	165	1e-47	161	46	65	GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
32	P51154	194	RB22A_CANFA Ras-related protein Rab-22A OS=Ca...	165	2e-47	160	46	66	GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
33	Q9H0T7	212	RAB17_HUMAN Ras-related protein Rab-17 OS=Hom...	172	6e-47	159	46	70	GO:0005622; C:intracellular; IDA:LIFEdb.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
34	Q9SID8	207	RAH1D_ARATH Ras-related protein RABH1d OS=Ara...	207	1e-46	159	40	60	GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:TAIR.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
35	Q9LFT9	207	RAH1E_ARATH Ras-related protein RABH1e OS=Ara...	210	3e-46	157	39	60	GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
36	P17608	201	RYH1_SCHPO GTP-binding protein ryh1 OS=Schizo...	208	3e-46	157	38	61	GO:0005829; C:cytosol; IDA:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; TAS:PomBase.::GO:0003924; F:GTPase activity; ISS:PomBase.
									GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0006886; P:intracellular protein transport; ISS:PomBase.::GO:0042147; P:retrograde transport, endosome to Golgi; ISS:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IC:PomBase.
37	P34213	205	RAB6A_CAEEL Ras-related protein Rab-6.1 OS=Ca...	210	2e-45	155	39	57	GO:0031985; C:Golgi cisterna; IDA:WormBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:WormBase.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
38	Q54RX9	214	RAB5B_DICDI Putative ras-related protein Rab-...	165	5e-45	154	47	65
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
39	P35292	214	RAB17_MOUSE Ras-related protein Rab-17 OS=Mus...	181	6e-45	154	42	68	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
40	P61294	208	RAB6B_MOUSE Ras-related protein Rab-6B OS=Mus...	204	7e-45	154	37	60	GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
41	Q9NRW1	208	RAB6B_HUMAN Ras-related protein Rab-6B OS=Hom...	204	7e-45	154	37	60	GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; NAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
42	A6QR46	208	RAB6B_BOVIN Ras-related protein Rab-6B OS=Bos...	204	7e-45	154	37	60	GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
43	O80501	208	RAH1B_ARATH Ras-related protein RABH1b OS=Ara...	212	7e-45	154	37	58	GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0000139; C:Golgi membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
									GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:TAIR.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032940; P:secretion by cell; IGI:TAIR.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
44	Q1KME6	208	RAB6A_CHICK Ras-related protein Rab-6A OS=Gal...	205	1e-44	154	38	59	GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0000042; P:protein targeting to Golgi; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
45	Q9SMR4	214	RAH1C_ARATH Ras-related protein RABH1c OS=Ara...	166	1e-44	154	43	67	GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0000139; C:Golgi membrane; IDA:UniProtKB.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
46	P35282	222	RAB21_MOUSE Ras-related protein Rab-21 OS=Mus...	205	1e-44	154	39	60	GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
47	Q99260	215	YPT6_YEAST GTP-binding protein YPT6 OS=Saccha...	218	1e-44	154	38	62	GO:0005794; C:Golgi apparatus; TAS:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006886; P:intracellular protein transport; IGI:SGD.::GO:0042147; P:retrograde transport, endosome to Golgi; TAS:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
48	Q9WVB1	208	RAB6A_RAT Ras-related protein Rab-6A OS=Rattu...	203	2e-44	153	38	59	GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
									GO:0001671; F:ATPase activator activity; IDA:RGD.::GO:0051117; F:ATPase binding; IPI:RGD.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0000042; P:protein targeting to Golgi; ISS:UniProtKB.::GO:0032482; P:Rab protein signal transduction; IC:RGD.
49	P35279	208	RAB6A_MOUSE Ras-related protein Rab-6A OS=Mus...	203	2e-44	153	38	59	GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0000042; P:protein targeting to Golgi; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
50	Q5RAV6	208	RAB6A_PONAB Ras-related protein Rab-6A OS=Pon...	205	2e-44	153	38	58	GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0000042; P:protein targeting to Golgi; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
51	P20340	208	RAB6A_HUMAN Ras-related protein Rab-6A OS=Hom...	205	2e-44	153	38	58	GO:0031410; C:cytoplasmic vesicle; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005802; C:trans-Golgi network; IDA:BHF-UCL.
									GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.
									GO:0072385; P:minus-end-directed organelle transport along microtubule; TAS:BHF-UCL.::GO:0018125; P:peptidyl-cysteine methylation; IDA:MGI.::GO:0000042; P:protein targeting to Golgi; IDA:UniProtKB.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
52	Q9UL25	225	RAB21_HUMAN Ras-related protein Rab-21 OS=Hom...	208	6e-44	152	38	58	GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; IDA:UniProtKB.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
53	P90726	202	RAB18_CAEBR Ras-related protein Rab-18 OS=Cae...	210	8e-44	151	41	57	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; IEA:InterPro.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
54	Q6AXT5	223	RAB21_RAT Ras-related protein Rab-21 OS=Rattu...	196	1e-43	151	41	61	GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
55	Q17R06	222	RAB21_BOVIN Ras-related protein Rab-21 OS=Bos...	196	1e-43	151	40	61	GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
56	Q22782	205	RAB6B_CAEEL Ras-related protein Rab-6.2 OS=Ca...	165	2e-43	150	43	64	GO:0031985; C:Golgi cisterna; IDA:WormBase.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:WormBase.
									GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0016477; P:cell migration; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
57	P55745	223	RAB21_CANFA Ras-related protein Rab-21 OS=Can...	196	2e-43	150	41	61	GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
58	O24466	216	RAE1A_ARATH Ras-related protein RABE1a OS=Ara...	201	3e-43	150	40	58	GO:0005829; C:cytosol; IDA:TAIR.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
59	Q8WQ53	229	RAB21_GEOCY Ras-related protein Rab-21 OS=Geo...	163	6e-43	149	43	67	GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
60	Q40522	222	RB11D_TOBAC Ras-related protein Rab11D OS=Nic...	188	7e-43	149	40	63	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
61	O04486	217	RAA2A_ARATH Ras-related protein RABA2a OS=Ara...	206	1e-42	149	39	57	GO:0009504; C:cell plate; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0000910; P:cytokinesis; IMP:TAIR.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.

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