Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR086C
Length:
1186
Number of sequences:
5887
Description:
YOR086C TCB1 SGDID:S000005612, Chr XV from 486779-483219, Genome Release 64-1-1, reverse complement, Verified ORF, "Lipid-binding protein containing three calcium and lipid binding domains; non-tagged protein localizes to mitochondria and GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q7LZQ8    671   KPCB_XENLA Protein kinase C beta type OS=Xeno...975.5     34.7     26     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0035403; F:histone kinase activity (H3-T6 specific); ISS:UniProtKB.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
62Q9QYX7    5038   PCLO_MOUSE Protein piccolo OS=Mus musculus (M...980.0000008     57.8     34     52GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IDA:UniProtKB.
GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.::GO:0005522; F:profilin binding; IDA:UniProtKB.
GO:0019933; P:cAMP-mediated signaling; IDA:MGI.::GO:0007010; P:cytoskeleton organization; IDA:MGI.::GO:0030073; P:insulin secretion; IDA:MGI.::GO:0017157; P:regulation of exocytosis; IDA:MGI.::GO:0016080; P:synaptic vesicle targeting; NAS:UniProtKB.
63P47861    386   SYT5_RAT Synaptotagmin-5 OS=Rattus norvegicus...1005.2     34.7     29     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005544; F:calcium-dependent phospholipid binding; IDA:BHF-UCL.::GO:0030276; F:clathrin binding; IDA:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019905; F:syntaxin binding; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0017156; P:calcium ion-dependent exocytosis; NAS:RGD.
64O00445    386   SYT5_HUMAN Synaptotagmin-5 OS=Homo sapiens (H...912.6     35.8     29     57GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:ProtInc.
65Q14183    400   DOC2A_HUMAN Double C2-like domain-containing ...981.8     36.2     29     51GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0007399; P:nervous system development; TAS:ProtInc.::GO:0017158; P:regulation of calcium ion-dependent exocytosis; IMP:UniProtKB.
66Q5BJS7    553   CPNE9_RAT Copine-9 OS=Rattus norvegicus (Rat)...940.000001     56.2     35     49
67Q1RLL3    553   CPNE9_MOUSE Copine-9 OS=Mus musculus (Mouse)....940.000001     56.2     35     49
68Q8IYJ1    553   CPNE9_HUMAN Copine-9 OS=Homo sapiens (Human)....940.000001     56.2     35     49
69P47191    424   SYT1_CHICK Synaptotagmin-1 OS=Gallus gallus (...886     34.7     30     48GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IEA:InterPro.
70P70169    412   DOC2B_MOUSE Double C2-like domain-containing ...1140.16     39.7     32     46GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0008021; C:synaptic vesicle; IEA:InterPro.
GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.::GO:0019905; F:syntaxin binding; IPI:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0048791; P:calcium ion-dependent exocytosis of neurotransmitter; IMP:UniProtKB.::GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; ISS:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:0031340; P:positive regulation of vesicle fusion; ISS:UniProtKB.::GO:0008104; P:protein localization; IMP:UniProtKB.
71P70610    412   DOC2B_RAT Double C2-like domain-containing pr...1140.12     40     32     46GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0008021; C:synaptic vesicle; IEA:InterPro.
GO:0005544; F:calcium-dependent phospholipid binding; IDA:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0048791; P:calcium ion-dependent exocytosis of neurotransmitter; IDA:UniProtKB.::GO:0006887; P:exocytosis; IEP:RGD.::GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; IDA:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.::GO:0031340; P:positive regulation of vesicle fusion; IDA:UniProtKB.::GO:0008104; P:protein localization; ISS:UniProtKB.
72Q9R0N5    386   SYT5_MOUSE Synaptotagmin-5 OS=Mus musculus (M...967.7     34.3     29     51GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0031045; C:dense core granule; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043005; C:neuron projection; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro.
73Q9HCH3    593   CPNE5_HUMAN Copine-5 OS=Homo sapiens (Human)....970.000002     55.5     34     51
74Q8JZW4    593   CPNE5_MOUSE Copine-5 OS=Mus musculus (Mouse)....970.000002     55.5     34     51GO:0043005; C:neuron projection; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.
75Q5M7N9    889   ESYT3_XENTR Extended synaptotagmin-3 OS=Xenop...531.2     37     38     60GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
76P24507    537   SY63_DISOM Synaptotagmin-C OS=Discopyge ommat...1230.0008     47.4     28     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
77Q14184    412   DOC2B_HUMAN Double C2-like domain-containing ...1140.092     40.4     32     46GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0008021; C:synaptic vesicle; IEA:InterPro.
GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0048791; P:calcium ion-dependent exocytosis of neurotransmitter; ISS:UniProtKB.::GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; ISS:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.::GO:0031340; P:positive regulation of vesicle fusion; ISS:UniProtKB.::GO:0008104; P:protein localization; ISS:UniProtKB.
78P34693    441   SYT1_CAEEL Synaptotagmin-1 OS=Caenorhabditis ...962.1     35.8     32     52GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
79P24506    439   SY62_DISOM Synaptotagmin-B OS=Discopyge ommat...1129.8     33.9     29     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
80Q9PU36    5120   PCLO_CHICK Protein piccolo OS=Gallus gallus (...1070.000007     54.7     34     48GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.::GO:0005522; F:profilin binding; ISS:UniProtKB.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.
81P40748    588   SYT3_RAT Synaptotagmin-3 OS=Rattus norvegicus...1490.002     45.8     28     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; TAS:RGD.::GO:0005544; F:calcium-dependent phospholipid binding; IDA:RGD.::GO:0030276; F:clathrin binding; IDA:BHF-UCL.::GO:0019905; F:syntaxin binding; IDA:RGD.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0017156; P:calcium ion-dependent exocytosis; TAS:RGD.::GO:0016079; P:synaptic vesicle exocytosis; TAS:RGD.
82Q5DTI8    891   ESYT3_MOUSE Extended synaptotagmin-3 OS=Mus m...760.89     37.4     32     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
83Q6PFQ7    802   RASL2_MOUSE Ras GTPase-activating protein 4 O...980.76     37.7     23     50GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
84Q9DC53    564   CPNE8_MOUSE Copine-8 OS=Mus musculus (Mouse)....890.00001     53.1     35     49
85O35681    587   SYT3_MOUSE Synaptotagmin-3 OS=Mus musculus (M...1490.002     45.8     28     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro.
86Q86YQ8    564   CPNE8_HUMAN Copine-8 OS=Homo sapiens (Human)....890.00001     53.1     35     49
87Q9BQG1    590   SYT3_HUMAN Synaptotagmin-3 OS=Homo sapiens (H...1490.007     44.3     28     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005768; C:endosome; IDA:LIFEdb.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
88P13677    700   KPC2_DROME Protein kinase C, eye isozyme OS=D...1090.00002     52.8     34     55GO:0016027; C:inaD signaling complex; TAS:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; ISS:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016062; P:adaptation of rhodopsin mediated signaling; IMP:FlyBase.::GO:0019722; P:calcium-mediated signaling; TAS:FlyBase.::GO:0006928; P:cellular component movement; IMP:FlyBase.::GO:0016059; P:deactivation of rhodopsin mediated signaling; IMP:FlyBase.::GO:0008585; P:female gonad development; IMP:FlyBase.::GO:0030845; P:inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway; IMP:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0045471; P:response to ethanol; IDA:FlyBase.
89Q86KB1    617   ADCB_DICDI Arrestin domain-containing protein...780.17     39.7     31     54
GO:0007165; P:signal transduction; IEA:InterPro.
90P47709    684   RP3A_RAT Rabphilin-3A OS=Rattus norvegicus (R...961.4     37     31     51GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:RGD.::GO:0019898; C:extrinsic to membrane; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0030141; C:secretory granule; IDA:RGD.::GO:0030672; C:synaptic vesicle membrane; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD.
GO:0005509; F:calcium ion binding; IDA:RGD.::GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:RGD.::GO:0042301; F:phosphate ion binding; IDA:RGD.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0008430; F:selenium binding; IDA:RGD.::GO:0005215; F:transporter activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:RGD.
GO:0007420; P:brain development; IEP:RGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.
91P47708    681   RP3A_MOUSE Rabphilin-3A OS=Mus musculus (Mous...961.1     37     31     51GO:0030054; C:cell junction; IEA:UniProtKB-KW.
GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
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