rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P63319 | 697 | KPCG_RAT Protein kinase C gamma type OS=Rattu... | 96 | 0.63 | 37.7 | 28 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004698; F:calcium-dependent protein kinase C activity; IDA:RGD.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; NAS:RGD.::GO:0007611; P:learning or memory; IEP:RGD.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB.::GO:0007268; P:synaptic transmission; NAS:RGD. | 32 | P63318 | 697 | KPCG_MOUSE Protein kinase C gamma type OS=Mus... | 96 | 0.63 | 37.7 | 28 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0097060; C:synaptic membrane; IDA:UniProtKB.::GO:0019717; C:synaptosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007635; P:chemosensory behavior; IMP:MGI.::GO:0060384; P:innervation; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; IMP:UniProtKB.::GO:0048265; P:response to pain; IMP:UniProtKB.::GO:0007268; P:synaptic transmission; IMP:UniProtKB. | 33 | Q8N9I0 | 419 | SYT2_HUMAN Synaptotagmin-2 OS=Homo sapiens (H... | 111 | 7.6 | 34.3 | 29 | 51 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0007269; P:neurotransmitter secretion; TAS:Reactome. | 34 | P29101 | 422 | SYT2_RAT Synaptotagmin-2 OS=Rattus norvegicus... | 111 | 7.3 | 34.3 | 29 | 51 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; TAS:RGD. | | | | | | | | | | GO:0005509; F:calcium ion binding; TAS:RGD.::GO:0005544; F:calcium-dependent phospholipid binding; IDA:BHF-UCL.::GO:0019905; F:syntaxin binding; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0016079; P:synaptic vesicle exocytosis; TAS:RGD. | 35 | P20444 | 672 | KPCA_MOUSE Protein kinase C alpha type OS=Mus... | 136 | 6 | 34.7 | 21 | 46 | GO:0030425; C:dendrite; IDA:MGI.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0001750; C:photoreceptor outer segment; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004698; F:calcium-dependent protein kinase C activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006874; P:cellular calcium ion homeostasis; IMP:MGI.::GO:0071322; P:cellular response to carbohydrate stimulus; IDA:MGI.::GO:0002062; P:chondrocyte differentiation; IDA:MGI.::GO:0000188; P:inactivation of MAPK activity; IMP:MGI.::GO:0008629; P:induction of apoptosis by intracellular signals; IMP:MGI.::GO:0050930; P:induction of positive chemotaxis; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0046325; P:negative regulation of glucose import; IMP:MGI.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:MGI.::GO:0001933; P:negative regulation of protein phosphorylation; IMP:MGI.::GO:0030593; P:neutrophil chemotaxis; IMP:MGI.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; IMP:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0050729; P:positive regulation of inflammatory response; IMP:MGI.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; IMP:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:MGI.::GO:0006937; P:regulation of muscle contraction; IMP:MGI.::GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0090330; P:regulation of platelet aggregation; IMP:UniProtKB.::GO:0002026; P:regulation of the force of heart contraction; IMP:MGI. | 36 | P41885 | 1106 | RBF1_CAEEL Rabphilin-1 OS=Caenorhabditis eleg... | 61 | 0.15 | 40 | 31 | 56 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.::GO:0008021; C:synaptic vesicle; IDA:WormBase. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0005215; F:transporter activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase. | 37 | Q8CFI0 | 1004 | NED4L_MOUSE E3 ubiquitin-protein ligase NEDD4... | 98 | 0.001 | 46.6 | 30 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0019871; F:sodium channel inhibitor activity; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0010766; P:negative regulation of sodium ion transport; IDA:MGI.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 38 | A8KBH6 | 670 | KPCB_XENTR Protein kinase C beta type OS=Xeno... | 97 | 7.8 | 34.3 | 26 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0035403; F:histone kinase activity (H3-T6 specific); ISS:UniProtKB.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 39 | Q5RBF2 | 959 | NED4L_PONAB E3 ubiquitin-protein ligase NEDD4... | 75 | 0.002 | 46.2 | 31 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro. | | | | | | | | | | | 40 | Q96PU5 | 975 | NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4... | 75 | 0.002 | 46.2 | 31 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006883; P:cellular sodium ion homeostasis; NAS:UniProtKB.::GO:0007588; P:excretion; NAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0045807; P:positive regulation of endocytosis; NAS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0042176; P:regulation of protein catabolic process; NAS:UniProtKB.::GO:0010038; P:response to metal ion; IDA:UniProtKB.::GO:0006814; P:sodium ion transport; NAS:UniProtKB.::GO:0030104; P:water homeostasis; NAS:UniProtKB. | 41 | P05128 | 682 | KPCG_BOVIN Protein kinase C gamma type OS=Bos... | 105 | 0.42 | 38.5 | 27 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB. | 42 | P10829 | 697 | KPCG_RABIT Protein kinase C gamma type OS=Ory... | 105 | 0.44 | 38.5 | 27 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB. | 43 | Q9Z1X1 | 1088 | ESYT1_RAT Extended synaptotagmin-1 OS=Rattus ... | 57 | 0.59 | 38.1 | 37 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 44 | Q9Y6V0 | 5065 | PCLO_HUMAN Protein piccolo OS=Homo sapiens (H... | 64 | 9.6 | 34.3 | 36 | 56 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; NAS:UniProtKB.::GO:0016020; C:membrane; IEA:InterPro.::GO:0008021; C:synaptic vesicle; IEA:InterPro. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.::GO:0005522; F:profilin binding; ISS:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0016079; P:synaptic vesicle exocytosis; NAS:UniProtKB. | 45 | Q4R4U2 | 697 | KPCG_MACFA Protein kinase C gamma type OS=Mac... | 111 | 0.47 | 38.5 | 25 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB. | 46 | P04409 | 672 | KPCA_BOVIN Protein kinase C alpha type OS=Bos... | 76 | 0.55 | 38.1 | 38 | 50 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB. | 47 | P05129 | 697 | KPCG_HUMAN Protein kinase C gamma type OS=Hom... | 111 | 0.3 | 38.9 | 26 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0042177; P:negative regulation of protein catabolic process; IDA:HGNC.::GO:0031397; P:negative regulation of protein ubiquitination; IDA:HGNC.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0032425; P:positive regulation of mismatch repair; IDA:HGNC.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 48 | Q9BSJ8 | 1104 | ESYT1_HUMAN Extended synaptotagmin-1 OS=Homo ... | 57 | 0.57 | 38.1 | 35 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 49 | Q9JKS6 | 5085 | PCLO_RAT Protein piccolo OS=Rattus norvegicus... | 98 | 0.0000004 | 58.5 | 34 | 52 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IDA:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0005544; F:calcium-dependent phospholipid binding; IDA:UniProtKB.::GO:0005522; F:profilin binding; ISS:UniProtKB. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0016080; P:synaptic vesicle targeting; NAS:UniProtKB. | 50 | P21707 | 421 | SYT1_RAT Synaptotagmin-1 OS=Rattus norvegicus... | 88 | 3.3 | 35.4 | 32 | 48 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0031045; C:dense core granule; IDA:RGD.::GO:0060076; C:excitatory synapse; IDA:BHF-UCL.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.::GO:0030672; C:synaptic vesicle membrane; TAS:RGD. | | | | | | | | | | GO:0005509; F:calcium ion binding; TAS:RGD.::GO:0005544; F:calcium-dependent phospholipid binding; IDA:BHF-UCL.::GO:0005516; F:calmodulin binding; IDA:RGD.::GO:0030276; F:clathrin binding; IDA:BHF-UCL.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0019905; F:syntaxin binding; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0017156; P:calcium ion-dependent exocytosis; TAS:RGD.::GO:0017158; P:regulation of calcium ion-dependent exocytosis; IMP:RGD.::GO:0016079; P:synaptic vesicle exocytosis; TAS:RGD. | 51 | Q60HC0 | 419 | SYT1_MACFA Synaptotagmin-1 OS=Macaca fascicul... | 88 | 3.1 | 35.4 | 32 | 48 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | | 52 | P46096 | 421 | SYT1_MOUSE Synaptotagmin-1 OS=Mus musculus (M... | 88 | 3.4 | 35.4 | 32 | 48 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043005; C:neuron projection; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:UniProtKB.::GO:0042734; C:presynaptic membrane; IDA:MGI.::GO:0030672; C:synaptic vesicle membrane; IDA:MGI. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:MGI.::GO:0005544; F:calcium-dependent phospholipid binding; TAS:MGI.::GO:0048306; F:calcium-dependent protein binding; IPI:HGNC.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0016079; P:synaptic vesicle exocytosis; IMP:MGI. | 53 | P48018 | 422 | SYT1_BOVIN Synaptotagmin-1 OS=Bos taurus (Bov... | 88 | 3 | 35.4 | 32 | 48 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | | 54 | P21579 | 422 | SYT1_HUMAN Synaptotagmin-1 OS=Homo sapiens (H... | 88 | 3.2 | 35.4 | 32 | 48 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0060201; C:clathrin sculpted acetylcholine transport vesicle membrane; TAS:Reactome.::GO:0061202; C:clathrin sculpted gamma-aminobutyric acid transport vesicle membrane; TAS:Reactome.::GO:0060203; C:clathrin sculpted glutamate transport vesicle membrane; TAS:Reactome.::GO:0070083; C:clathrin sculpted monoamine transport vesicle membrane; TAS:Reactome.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; TAS:UniProtKB.::GO:0050750; F:low-density lipoprotein particle receptor binding; IDA:MGI.::GO:0017075; F:syntaxin-1 binding; TAS:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0005513; P:detection of calcium ion; TAS:UniProtKB.::GO:0014047; P:glutamate secretion; TAS:Reactome.::GO:0051260; P:protein homooligomerization; TAS:UniProtKB. | 55 | Q5R4J5 | 419 | SYT1_PONAB Synaptotagmin-1 OS=Pongo abelii (S... | 88 | 3.3 | 35.4 | 32 | 48 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | | 56 | P70611 | 403 | DOC2A_RAT Double C2-like domain-containing pr... | 98 | 1.9 | 36.2 | 29 | 51 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0016079; P:synaptic vesicle exocytosis; IEP:RGD. | 57 | Q7TNF0 | 405 | DOC2A_MOUSE Double C2-like domain-containing ... | 98 | 1.8 | 36.2 | 29 | 51 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0017158; P:regulation of calcium ion-dependent exocytosis; IMP:UniProtKB. | 58 | Q5RAG2 | 1104 | ESYT1_PONAB Extended synaptotagmin-1 OS=Pongo... | 57 | 0.56 | 38.1 | 35 | 58 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 59 | A0FGR9 | 886 | ESYT3_HUMAN Extended synaptotagmin-3 OS=Homo ... | 98 | 0.22 | 39.7 | 29 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 60 | P05130 | 679 | KPC1_DROME Protein kinase C, brain isozyme OS... | 102 | 2 | 36.2 | 28 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 61 | Q7LZQ8 | 671 | KPCB_XENLA Protein kinase C beta type OS=Xeno... | 97 | 5.5 | 34.7 | 26 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0035403; F:histone kinase activity (H3-T6 specific); ISS:UniProtKB.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |