Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR086C
Length:
1186
Number of sequences:
5887
Description:
YOR086C TCB1 SGDID:S000005612, Chr XV from 486779-483219, Genome Release 64-1-1, reverse complement, Verified ORF, "Lipid-binding protein containing three calcium and lipid binding domains; non-tagged protein localizes to mitochondria and GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211Q8N3E9    789   PLCD3_HUMAN 1-phosphatidylinositol 4,5-bispho...750.17     39.7     29     51GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
212Q7TPS5    1016   K0528_MOUSE Uncharacterized protein KIAA0528 ...890.19     39.7     34     52GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005509; F:calcium ion binding; IDA:MGI.
GO:2001275; P:positive regulation of glucose import in response to insulin stimulus; IMP:MGI.::GO:0072659; P:protein localization in plasma membrane; IMP:MGI.::GO:0006906; P:vesicle fusion; IMP:MGI.
213Q86YS7    1000   K0528_HUMAN Uncharacterized protein KIAA0528 ...890.19     39.7     34     52
214Q5RDC8    1000   K0528_PONAB Uncharacterized protein KIAA0528 ...890.2     39.7     34     52
215Q99N80    567   SYTL1_MOUSE Synaptotagmin-like protein 1 OS=M...800.2     39.3     30     53GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; IDA:UniProtKB.::GO:0042470; C:melanosome; IDA:UniProtKB.::GO:0005625; C:soluble fraction; IDA:UniProtKB.
GO:0042043; F:neurexin family protein binding; IDA:UniProtKB.::GO:0017137; F:Rab GTPase binding; IEA:InterPro.
GO:0006887; P:exocytosis; IDA:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.
216O23078    927   PLDB2_ARATH Phospholipase D beta 2 OS=Arabido...1130.21     39.7     26     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0070290; F:NAPE-specific phospholipase D activity; IEA:EC.::GO:0004630; F:phospholipase D activity; IDA:TAIR.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro.
217Q9ZT46    138   PP16B_CUCMA 16 kDa phloem protein 2 OS=Cucurb...840.23     37.4     24     45
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006810; P:transport; IEA:UniProtKB-KW.
218Q9R0Q1    673   SYTL4_MOUSE Synaptotagmin-like protein 4 OS=M...950.23     39.3     33     54GO:0019898; C:extrinsic to membrane; IDA:UniProtKB.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0042043; F:neurexin family protein binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IDA:MGI.::GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0006887; P:exocytosis; IDA:MGI.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0046676; P:negative regulation of insulin secretion; IMP:MGI.
219P10820    554   PERF_MOUSE Perforin-1 OS=Mus musculus (Mouse)...1280.3     38.9     27     41GO:0044194; C:cytolytic granule; IDA:UniProtKB.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI.::GO:0031904; C:endosome lumen; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0022829; F:wide pore channel activity; IDA:UniProtKB.
GO:0019835; P:cytolysis; IMP:UniProtKB.::GO:0002357; P:defense response to tumor cell; IMP:UniProtKB.::GO:0051607; P:defense response to virus; IMP:UniProtKB.::GO:0002418; P:immune response to tumor cell; IMP:UniProtKB.::GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
220Q9R189    1088   UN13D_RAT Protein unc-13 homolog D OS=Rattus ...1291.3     37     26     42GO:0005770; C:late endosome; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell.
221B2RUP2    1085   UN13D_MOUSE Protein unc-13 homolog D OS=Mus m...1820.71     37.7     19     36GO:0005770; C:late endosome; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051607; P:defense response to virus; IMP:MGI.::GO:0002467; P:germinal center formation; IMP:MGI.::GO:0002432; P:granuloma formation; IMP:MGI.::GO:0043320; P:natural killer cell degranulation; IMP:MGI.::GO:0006909; P:phagocytosis; IMP:MGI.
222P93733    1083   PLDB1_ARATH Phospholipase D beta 1 OS=Arabido...710.46     38.5     32     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0070290; F:NAPE-specific phospholipase D activity; IEA:EC.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:TAIR.::GO:0004630; F:phospholipase D activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:TAIR.
GO:0009816; P:defense response to bacterium, incompatible interaction; IEP:TAIR.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0046686; P:response to cadmium ion; IEP:TAIR.
223Q96FN4    548   CPNE2_HUMAN Copine-2 OS=Homo sapiens (Human)....1140.54     38.1     25     49
224Q9PUN2    731   SMUF1_XENLA E3 ubiquitin-protein ligase SMURF...650.63     37.7     32     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0030509; P:BMP signaling pathway; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IDA:UniProtKB.::GO:0007398; P:ectoderm development; TAS:UniProtKB.::GO:0030514; P:negative regulation of BMP signaling pathway; TAS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
225A2A5Z6    748   SMUF2_MOUSE E3 ubiquitin-protein ligase SMURF...1090.68     37.7     28     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
226Q925B4    395   SYT8_RAT Synaptotagmin-8 OS=Rattus norvegicus...1702.1     35.8     27     44GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; IEA:InterPro.
GO:0030276; F:clathrin binding; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro.
227Q9HAU4    748   SMUF2_HUMAN E3 ubiquitin-protein ligase SMURF...1090.73     37.7     28     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046332; F:SMAD binding; IPI:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0030509; P:BMP signaling pathway; TAS:Reactome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; NAS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.::GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IDA:BHF-UCL.
228Q7L804    512   RFIP2_HUMAN Rab11 family-interacting protein ...1050.83     37.4     30     47GO:0030659; C:cytoplasmic vesicle membrane; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.
GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0030010; P:establishment of cell polarity; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0006833; P:water transport; TAS:Reactome.
229Q70J99    1090   UN13D_HUMAN Protein unc-13 homolog D OS=Homo ...971.5     37     21     45GO:0070382; C:exocytic vesicle; IDA:UniProtKB.::GO:0005770; C:late endosome; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; IMP:UniProtKB.
230A9JRZ0    765   SMUF2_DANRE E3 ubiquitin-protein ligase SMURF...1091     37.4     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
231A1D3C5    816   RSP5_NEOFI Probable E3 ubiquitin-protein liga...691.1     37.4     32     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB.
232A4IJ05    474   SYT17_XENTR Synaptotagmin-17 OS=Xenopus tropi...781.1     37     29     53GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; IEA:InterPro.
GO:0005215; F:transporter activity; IEA:InterPro.
233Q54P51    539   CPNC_DICDI Copine-C OS=Dictyostelium discoide...691.1     37     35     49
GO:0005544; F:calcium-dependent phospholipid binding; ISS:dictyBase.::GO:0005215; F:transporter activity; ISS:dictyBase.
GO:0006629; P:lipid metabolic process; ISS:dictyBase.::GO:0016192; P:vesicle-mediated transport; ISS:dictyBase.
234P10688    756   PLCD1_RAT 1-phosphatidylinositol 4,5-bisphosp...531.3     37     32     55GO:0005829; C:cytosol; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0031966; C:mitochondrial membrane; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.
GO:0005509; F:calcium ion binding; IDA:RGD.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:RGD.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:RGD.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0051482; P:elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger; IMP:RGD.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0032962; P:positive regulation of inositol trisphosphate biosynthetic process; IMP:RGD.::GO:0010701; P:positive regulation of norepinephrine secretion; IMP:RGD.::GO:0010044; P:response to aluminum ion; IEP:RGD.::GO:0051592; P:response to calcium ion; IMP:RGD.::GO:0055093; P:response to hyperoxia; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.::GO:0043434; P:response to peptide hormone stimulus; IMP:RGD.::GO:0034696; P:response to prostaglandin F stimulus; IEP:RGD.
235Q9R0N6    395   SYT8_MOUSE Synaptotagmin-8 OS=Mus musculus (M...1741.3     36.6     27     44GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031988; C:membrane-bounded vesicle; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; IEA:InterPro.
GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0007340; P:acrosome reaction; IDA:HGNC.
236A2QQ28    821   RSP5_ASPNC Probable E3 ubiquitin-protein liga...631.5     36.6     30     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB.
237Q944C2    578   PLCD5_ARATH Phosphoinositide phospholipase C ...561.5     36.6     34     57GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
238B8N7E5    812   RSP5_ASPFN Probable E3 ubiquitin-protein liga...631.6     36.6     30     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
239Q2UBP1    816   RSP5_ASPOR Probable E3 ubiquitin-protein liga...631.6     36.6     30     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
240Q0CCL1    808   RSP5_ASPTN Probable E3 ubiquitin-protein liga...631.7     36.6     30     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB.
241Q9HCE7    757   SMUF1_HUMAN E3 ubiquitin-protein ligase SMURF...827.1     34.7     30     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.
GO:0048185; F:activin binding; IPI:BHF-UCL.::GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.::GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0030509; P:BMP signaling pathway; IDA:UniProtKB.::GO:0030154; P:cell differentiation; IDA:UniProtKB.::GO:0007398; P:ectoderm development; TAS:UniProtKB.::GO:0030514; P:negative regulation of BMP signaling pathway; TAS:UniProtKB.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:BHF-UCL.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0006611; P:protein export from nucleus; IDA:BHF-UCL.::GO:0034394; P:protein localization at cell surface; IDA:BHF-UCL.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0032801; P:receptor catabolic process; IDA:BHF-UCL.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.::GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IDA:BHF-UCL.
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