Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR086C
Length:
1186
Number of sequences:
5887
Description:
YOR086C TCB1 SGDID:S000005612, Chr XV from 486779-483219, Genome Release 64-1-1, reverse complement, Verified ORF, "Lipid-binding protein containing three calcium and lipid binding domains; non-tagged protein localizes to mitochondria and GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151Q8BT60    533   CPNE3_MOUSE Copine-3 OS=Mus musculus (Mouse)....951.1     37     26     48GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
152Q8NB66    2214   UN13C_HUMAN Protein unc-13 homolog C OS=Homo ...840.049     41.6     35     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
153Q55CH0    654   ADCC_DICDI Arrestin domain-containing protein...794     35.4     30     51
GO:0007165; P:signal transduction; IEA:InterPro.
154O77793    749   PA24A_HORSE Cytosolic phospholipase A2 OS=Equ...790.004     45.1     30     54GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.::GO:0004622; F:lysophospholipase activity; IEA:EC.::GO:0004623; F:phospholipase A2 activity; ISS:UniProtKB.
GO:0009395; P:phospholipid catabolic process; IEA:InterPro.
155O75923    2080   DYSF_HUMAN Dysferlin OS=Homo sapiens (Human)....938     34.7     27     47GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
GO:0005544; F:calcium-dependent phospholipid binding; IMP:UniProtKB.
156Q7ZWU7    876   EST2B_XENLA Extended synaptotagmin-2-B OS=Xen...3300.013     43.5     22     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
157Q9R0N3    430   SYT11_MOUSE Synaptotagmin-11 OS=Mus musculus ...1772.1     36.2     24     41GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005887; C:integral to plasma membrane; IDA:MGI.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IEA:InterPro.
158Q9BT88    431   SYT11_HUMAN Synaptotagmin-11 OS=Homo sapiens ...1011.8     36.2     29     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005215; F:transporter activity; IEA:InterPro.
159B3DLH6    1929   MYOF_XENTR Myoferlin OS=Xenopus tropicalis (W...910.58     38.1     34     45GO:0005901; C:caveola; ISS:UniProtKB.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; ISS:UniProtKB.
GO:0001778; P:plasma membrane repair; ISS:UniProtKB.
160P27715    2155   UNC13_CAEEL Phorbol ester/diacylglycerol-bind...542.3     36.2     37     50GO:0048786; C:presynaptic active zone; IDA:WormBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007411; P:axon guidance; IMP:WormBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0046662; P:regulation of oviposition; IMP:WormBase.::GO:0043051; P:regulation of pharyngeal pumping; IMP:WormBase.
161Q5FWL4    872   EST2A_XENLA Extended synaptotagmin-2-A OS=Xen...525.3     35     40     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
162P40749    425   SYT4_MOUSE Synaptotagmin-4 OS=Mus musculus (M...920.006     44.3     34     53GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; TAS:UniProtKB.::GO:0043005; C:neuron projection; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IDA:MGI.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0007269; P:neurotransmitter secretion; IDA:MGI.::GO:0017158; P:regulation of calcium ion-dependent exocytosis; TAS:UniProtKB.::GO:0048489; P:synaptic vesicle transport; TAS:UniProtKB.
163Q9H2B2    425   SYT4_HUMAN Synaptotagmin-4 OS=Homo sapiens (H...1567.2     34.3     25     40GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IEA:InterPro.
164Q9Y0H4    949   SUDX_DROME E3 ubiquitin-protein ligase Su(dx)...772.2     36.2     34     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0005112; F:Notch binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0016348; P:imaginal disc-derived leg joint morphogenesis; IMP:UniProtKB.::GO:0008587; P:imaginal disc-derived wing margin morphogenesis; IGI:FlyBase.::GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IMP:UniProtKB.::GO:0019915; P:lipid storage; IDA:FlyBase.::GO:0045746; P:negative regulation of Notch signaling pathway; IGI:UniProtKB.::GO:0007219; P:Notch signaling pathway; IGI:FlyBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0035209; P:pupal development; IMP:UniProtKB.::GO:0031623; P:receptor internalization; IMP:UniProtKB.::GO:0032880; P:regulation of protein localization; IMP:FlyBase.::GO:0048190; P:wing disc dorsal/ventral pattern formation; IMP:UniProtKB.
165Q5RAE1    537   CPNE3_PONAB Copine-3 OS=Pongo abelii (Sumatra...955.4     34.7     27     45
166O08835    430   SYT11_RAT Synaptotagmin-11 OS=Rattus norvegic...1771.9     36.2     25     41GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IDA:RGD.::GO:0005544; F:calcium-dependent phospholipid binding; IDA:RGD.::GO:0005215; F:transporter activity; IEA:InterPro.
167O95294    804   RASL1_HUMAN RasGAP-activating-like protein 1 ...675.9     34.7     27     49GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; TAS:ProtInc.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
168Q8K0T7    2210   UN13C_MOUSE Protein unc-13 homolog C OS=Mus m...1030.13     40.4     31     48GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0001566; F:non-kinase phorbol ester receptor activity; TAS:MGI.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007268; P:synaptic transmission; IMP:MGI.
169Q5SSL4    859   ABR_MOUSE Active breakpoint cluster region-re...1540.009     43.9     27     45GO:0005829; C:cytosol; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IGI:MGI.::GO:0007420; P:brain development; IGI:MGI.::GO:0042472; P:inner ear morphogenesis; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030336; P:negative regulation of cell migration; IGI:MGI.::GO:0050728; P:negative regulation of inflammatory response; IMP:MGI.::GO:0043314; P:negative regulation of neutrophil degranulation; IGI:MGI.::GO:0050885; P:neuromuscular process controlling balance; IGI:MGI.::GO:0050766; P:positive regulation of phagocytosis; IGI:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI.
170A6QNS3    859   ABR_BOVIN Active breakpoint cluster region-re...1540.01     43.9     27     45
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
171Q99829    537   CPNE1_HUMAN Copine-1 OS=Homo sapiens (Human)....980.01     43.5     27     48
GO:0005544; F:calcium-dependent phospholipid binding; TAS:ProtInc.::GO:0001786; F:phosphatidylserine binding; IDA:MGI.::GO:0005215; F:transporter activity; TAS:ProtInc.
GO:0006629; P:lipid metabolic process; TAS:ProtInc.::GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
172Q12979    859   ABR_HUMAN Active breakpoint cluster region-re...1540.01     43.9     27     45GO:0005829; C:cytosol; TAS:Reactome.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
173Q9UPW8    1703   UN13A_HUMAN Protein unc-13 homolog A OS=Homo ...840.36     38.9     32     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
174P50232    425   SYT4_RAT Synaptotagmin-4 OS=Rattus norvegicus...920.011     43.1     32     53GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0030276; F:clathrin binding; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0017156; P:calcium ion-dependent exocytosis; NAS:RGD.::GO:0007269; P:neurotransmitter secretion; NAS:RGD.
175Q4KUS2    1712   UN13A_MOUSE Protein unc-13 homolog A OS=Mus m...840.37     38.9     32     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
GO:0019992; F:diacylglycerol binding; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; IGI:MGI.::GO:0016188; P:synaptic vesicle maturation; IMP:MGI.
176P47712    749   PA24A_HUMAN Cytosolic phospholipase A2 OS=Hom...790.014     43.5     29     53GO:0005829; C:cytosol; NAS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.
GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0005544; F:calcium-dependent phospholipid binding; IDA:UniProtKB.::GO:0004622; F:lysophospholipase activity; IEA:EC.
GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0006663; P:platelet activating factor biosynthetic process; NAS:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.
177O14795    1591   UN13B_HUMAN Protein unc-13 homolog B OS=Homo ...1037.6     34.7     28     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005794; C:Golgi apparatus; TAS:ProtInc.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; TAS:ProtInc.::GO:0004871; F:signal transducer activity; TAS:ProtInc.
GO:0007588; P:excretion; TAS:ProtInc.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
178Q6PAJ1    1270   BCR_MOUSE Breakpoint cluster region protein O...1170.015     43.5     31     49GO:0005829; C:cytosol; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0030675; F:Rac GTPase activator activity; IGI:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IGI:MGI.::GO:0007420; P:brain development; IGI:MGI.::GO:0042472; P:inner ear morphogenesis; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030336; P:negative regulation of cell migration; IGI:MGI.::GO:0050728; P:negative regulation of inflammatory response; IMP:MGI.::GO:0043314; P:negative regulation of neutrophil degranulation; IGI:MGI.::GO:0050885; P:neuromuscular process controlling balance; IGI:MGI.::GO:0050766; P:positive regulation of phagocytosis; IGI:MGI.::GO:0051726; P:regulation of cell cycle; IDA:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI.
179Q9NZM1    2061   MYOF_HUMAN Myoferlin OS=Homo sapiens (Human)....921.3     37     28     43GO:0005901; C:caveola; ISS:UniProtKB.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IDA:UniProtKB.
GO:0008015; P:blood circulation; TAS:ProtInc.::GO:0006936; P:muscle contraction; TAS:ProtInc.::GO:0001778; P:plasma membrane repair; ISS:UniProtKB.
180Q8K2J0    785   PLCD3_MOUSE 1-phosphatidylinositol 4,5-bispho...770.017     43.1     35     56GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0001525; P:angiogenesis; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0060716; P:labyrinthine layer blood vessel development; IGI:MGI.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0042127; P:regulation of cell proliferation; IGI:MGI.
181A3KGK3    1992   FR1L4_MOUSE Fer-1-like protein 4 OS=Mus muscu...810.17     40     31     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
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