Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR064C
Length:
219
Number of sequences:
5887
Description:
YOR064C YNG1 SGDID:S000005590, Chr XV from 446738-446079, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3, has similarity to the human tumor suppressor ING1"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31O88491    2588   NSD1_MOUSE Histone-lysine N-methyltransferase...588.4     31.2     38     53GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0035097; C:histone methyltransferase complex; IC:UniProtKB.
GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; IPI:UniProtKB.::GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:UniProtKB.::GO:0042799; F:histone methyltransferase activity (H4-K20 specific); IDA:UniProtKB.::GO:0016922; F:ligand-dependent nuclear receptor binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0046965; F:retinoid X receptor binding; IPI:UniProtKB.::GO:0046966; F:thyroid hormone receptor binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
32P34447    867   YM2A_CAEEL Uncharacterized protein F54F2.2, i...400.016     39.7     38     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0016246; P:RNA interference; IMP:WormBase.
33P55198    1093   AF17_HUMAN Protein AF-17 OS=Homo sapiens (Hum...460.026     38.9     39     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; TAS:ProtInc.
34Q96L73    2696   NSD1_HUMAN Histone-lysine N-methyltransferase...589.1     31.2     38     53GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; IDA:UniProtKB.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:UniProtKB.::GO:0042799; F:histone methyltransferase activity (H4-K20 specific); ISS:UniProtKB.::GO:0016922; F:ligand-dependent nuclear receptor binding; ISS:UniProtKB.::GO:0046965; F:retinoid X receptor binding; ISS:UniProtKB.::GO:0046966; F:thyroid hormone receptor binding; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
35Q5EAW9    845   TAF3_XENLA Transcription initiation factor TF...360.03     38.9     42     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
36Q5HZG4    932   TAF3_MOUSE Transcription initiation factor TF...370.044     38.1     41     65
GO:0002039; F:p53 binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:MGI.
37Q5F489    930   TAF3_CHICK Transcription initiation factor TF...360.058     37.7     44     69GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
38O54826    1068   AF10_MOUSE Protein AF-10 OS=Mus musculus (Mou...460.063     37.7     37     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
39P55197    1027   AF10_HUMAN Protein AF-10 OS=Homo sapiens (Hum...460.077     37.4     37     46GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
40Q9BZ95    1437   NSD3_HUMAN Histone-lysine N-methyltransferase...440.22     36.2     43     55GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IC:UniProtKB.
GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; NAS:UniProtKB.::GO:0016049; P:cell growth; NAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
41Q6P2L6    1439   NSD3_MOUSE Histone-lysine N-methyltransferase...440.23     36.2     43     55GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
42Q5VWG9    929   TAF3_HUMAN Transcription initiation factor TF...360.28     35.8     42     67GO:0005669; C:transcription factor TFIID complex; IDA:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051457; P:maintenance of protein location in nucleus; IDA:HGNC.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
43Q03012    353   SPP1_YEAST COMPASS component SPP1 OS=Saccharo...410.3     35.4     41     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IDA:SGD.::GO:0035064; F:methylated histone residue binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0051568; P:histone H3-K4 methylation; IDA:SGD.
44Q9UT79    1588   MSC1_SCHPO Multicopy suppressor of chk1 prote...490.88     34.3     33     53GO:0000118; C:histone deacetylase complex; IDA:PomBase.::GO:0000812; C:Swr1 complex; IDA:PomBase.
GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016573; P:histone acetylation; IMP:PomBase.::GO:0007126; P:meiosis; IMP:PomBase.::GO:0006974; P:response to DNA damage stimulus; IGI:PomBase.
45O96028    1365   NSD2_HUMAN Probable histone-lysine N-methyltr...351.7     33.5     37     63GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
46Q8BVE8    1365   NSD2_MOUSE Probable histone-lysine N-methyltr...353.8     32.3     34     63GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0003289; P:atrial septum primum morphogenesis; IMP:MGI.::GO:0003290; P:atrial septum secundum morphogenesis; IMP:MGI.::GO:0060348; P:bone development; IMP:MGI.::GO:0003149; P:membranous septum morphogenesis; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
47Q9W352    663   Y7446_DROME PHD finger and CXXC domain-contai...551.8     33.1     35     55GO:0048188; C:Set1C/COMPASS complex; IDA:FlyBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
48Q6E2N3    1163   TRI33_DANRE E3 ubiquitin-protein ligase TRIM3...1011.8     33.1     30     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
49Q5F3R2    1522   KDM5B_CHICK Lysine-specific demethylase 5B OS...631.9     33.1     30     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); ISS:UniProtKB.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); ISS:UniProtKB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
50P29375    1690   KDM5A_HUMAN Lysine-specific demethylase 5A OS...642.2     33.1     33     50GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IDA:GDB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
51E6ZGB4    1081   PHF2_DICLA Lysine-specific demethylase phf2 O...652.4     32.7     34     52GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0032454; F:histone demethylase activity (H3-K9 specific); ISS:UniProtKB.::GO:0005506; F:iron ion binding; ISS:UniProtKB.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
52Q04779    684   RCO1_YEAST Transcriptional regulatory protein...1152.6     32.7     29     43GO:0033698; C:Rpd3L complex; IDA:SGD.::GO:0032221; C:Rpd3S complex; IDA:SGD.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016575; P:histone deacetylation; IMP:SGD.::GO:0060195; P:negative regulation of antisense RNA transcription; IMP:SGD.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IMP:SGD.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IGI:SGD.
53Q8C9B9    2256   DIDO1_MOUSE Death-inducer obliterator 1 OS=Mu...393     32.7     44     56GO:0005737; C:cytoplasm; TAS:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.
54O75151    1096   PHF2_HUMAN Lysine-specific demethylase PHF2 O...683     32.7     37     53GO:0005730; C:nucleolus; IDA:UniProtKB.
GO:0032454; F:histone demethylase activity (H3-K9 specific); IDA:UniProtKB.::GO:0005506; F:iron ion binding; IDA:UniProtKB.::GO:0035064; F:methylated histone residue binding; IDA:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0001889; P:liver development; TAS:UniProtKB.::GO:0061188; P:negative regulation of chromatin silencing at rDNA; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
55Q6P949    1063   PHF2_DANRE Lysine-specific demethylase phf2 O...693.2     32.3     33     51GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0032454; F:histone demethylase activity (H3-K9 specific); ISS:UniProtKB.::GO:0005506; F:iron ion binding; ISS:UniProtKB.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0061188; P:negative regulation of chromatin silencing at rDNA; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
56Q8BSN5    401   PHF23_MOUSE PHD finger protein 23 OS=Mus musc...613.3     32.3     28     49
GO:0008270; F:zinc ion binding; IEA:InterPro.
57Q6AY75    334   PHF23_RAT PHD finger protein 23 OS=Rattus nor...613.3     32     28     49
GO:0008270; F:zinc ion binding; IEA:InterPro.
58Q9WTU0    1096   PHF2_MOUSE Lysine-specific demethylase PHF2 O...683.4     32.3     37     53GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0032454; F:histone demethylase activity (H3-K9 specific); ISS:UniProtKB.::GO:0005506; F:iron ion binding; ISS:UniProtKB.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0061188; P:negative regulation of chromatin silencing at rDNA; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
59B0STK1    268   PANB_LEPBP 3-methyl-2-oxobutanoate hydroxymet...833.7     32     31     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003864; F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
GO:0015940; P:pantothenate biosynthetic process; IEA:UniProtKB-KW.
60B0SAC5    268   PANB_LEPBA 3-methyl-2-oxobutanoate hydroxymet...833.7     32     31     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003864; F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
GO:0015940; P:pantothenate biosynthetic process; IEA:UniProtKB-KW.
61Q9BUL5    403   PHF23_HUMAN PHD finger protein 23 OS=Homo sap...615.1     31.6     28     49
GO:0008270; F:zinc ion binding; IEA:InterPro.
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