Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR061W
Length:
339
Number of sequences:
5887
Description:
YOR061W CKA2 SGDID:S000005587, Chr XV from 441534-442553, Genome Release 64-1-1, Verified ORF, "Alpha' catalytic subunit of casein kinase 2 (CK2), a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerase"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P19454    339   CSK22_YEAST Casein kinase II subunit alpha' O...3390     704     100     100GO:0005956; C:protein kinase CK2 complex; IDA:SGD.::GO:0034456; C:UTP-C complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0001300; P:chronological cell aging; IMP:SGD.::GO:0006356; P:regulation of transcription from RNA polymerase I promoter; IDA:SGD.::GO:0006359; P:regulation of transcription from RNA polymerase III promoter; IDA:SGD.::GO:0006974; P:response to DNA damage stimulus; IDA:SGD.
2P40231    332   CSK2A_SCHPO Casein kinase II subunit alpha OS...3239e-144     416     62     76GO:0005829; C:cytosol; IDA:PomBase.::GO:0005730; C:nucleolus; IDA:PomBase.::GO:0005956; C:protein kinase CK2 complex; TAS:PomBase.::GO:0031931; C:TORC1 complex; IDA:PomBase.::GO:0031932; C:TORC2 complex; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007163; P:establishment or maintenance of cell polarity; IMP:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase.
3Q8TG13    336   CSK2A_NEUCR Casein kinase II subunit alpha OS...3186e-134     392     64     76
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
4O64816    432   CSK2P_ARATH Casein kinase II subunit alpha, c...3195e-130     385     63     75GO:0005829; C:cytosol; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
5O76484    353   CSK2A_SPOFR Casein kinase II subunit alpha OS...3197e-129     379     61     75
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
6O64817    333   CSK23_ARATH Probable casein kinase II subunit...3191e-128     378     61     76
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
7Q08466    403   CSK22_ARATH Casein kinase II subunit alpha-2 ...3213e-127     377     61     76GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
8P28523    332   CSK2A_MAIZE Casein kinase II subunit alpha OS...3204e-127     374     62     75
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
9Q60737    391   CSK21_MOUSE Casein kinase II subunit alpha OS...3265e-126     374     60     75GO:0005956; C:protein kinase CK2 complex; TAS:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008013; F:beta-catenin binding; IPI:MGI.::GO:0019888; F:protein phosphatase regulator activity; IDA:MGI.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
10Q08467    409   CSK21_ARATH Casein kinase II subunit alpha-1 ...3275e-126     374     59     74
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
11P19139    391   CSK21_RAT Casein kinase II subunit alpha OS=R...3266e-126     373     60     75GO:0005956; C:protein kinase CK2 complex; TAS:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; NAS:RGD.::GO:0042127; P:regulation of cell proliferation; NAS:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
12P68400    391   CSK21_HUMAN Casein kinase II subunit alpha OS...3267e-126     373     60     75GO:0005829; C:cytosol; TAS:Reactome.::GO:0016581; C:NuRD complex; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; TAS:ProtInc.::GO:0016580; C:Sin3 complex; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051879; F:Hsp90 protein binding; TAS:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0061077; P:chaperone-mediated protein folding; TAS:UniProtKB.::GO:0071174; P:mitotic cell cycle spindle checkpoint; IMP:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
13P68399    391   CSK21_BOVIN Casein kinase II subunit alpha OS...3267e-126     373     60     75
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; ISS:AgBase.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
14P28020    392   CSK21_XENLA Casein kinase II subunit alpha OS...3249e-126     373     60     75
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
15P21868    391   CSK21_CHICK Casein kinase II subunit alpha OS...3242e-125     372     60     75
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
16P33674    391   CSK21_RABIT Casein kinase II subunit alpha OS...3266e-125     371     59     74
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
17P21869    350   CSK22_CHICK Casein kinase II subunit alpha' O...3191e-124     369     61     75
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
18P08181    336   CSK2A_DROME Casein kinase II subunit alpha OS...3191e-123     365     59     74GO:0005829; C:cytosol; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.::GO:0005956; C:protein kinase CK2 complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:FlyBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:FlyBase.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0022416; P:chaeta development; IMP:FlyBase.::GO:0048749; P:compound eye development; IMP:FlyBase.::GO:0046331; P:lateral inhibition; IMP:FlyBase.::GO:0045475; P:locomotor rhythm; IMP:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0031397; P:negative regulation of protein ubiquitination; IMP:FlyBase.::GO:0007228; P:positive regulation of hh target transcription factor activity; IMP:FlyBase.::GO:0045880; P:positive regulation of smoothened signaling pathway; IMP:FlyBase.::GO:0031647; P:regulation of protein stability; IMP:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; IDA:FlyBase.
19P20427    350   CSK22_BOVIN Casein kinase II subunit alpha' O...3192e-122     363     60     74
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
20O54833    350   CSK22_MOUSE Casein kinase II subunit alpha' O...3192e-122     363     60     74GO:0005956; C:protein kinase CK2 complex; TAS:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
21P19784    350   CSK22_HUMAN Casein kinase II subunit alpha' O...3193e-122     362     60     74GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
22P18334    360   CSK2A_CAEEL Casein kinase II subunit alpha OS...3242e-121     361     58     74GO:0030424; C:axon; IDA:UniProtKB.::GO:0005929; C:cilium; IDA:UniProtKB.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0034606; P:response to hermaphrodite contact; IMP:WormBase.::GO:0034608; P:vulval location; IMP:WormBase.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
23Q02720    337   CSK2A_DICDI Casein kinase II subunit alpha OS...3313e-121     360     59     73
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase.
24Q4U925    348   CSK2A_THEAN Casein kinase II subunit alpha OS...3187e-121     359     59     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
25P28547    348   CSK2A_THEPA Casein kinase II subunit alpha OS...3188e-121     358     59     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
26Q54LR6    605   Y6481_DICDI Probable serine/threonine-protein...3201e-113     349     53     71GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
27P15790    372   CSK21_YEAST Casein kinase II subunit alpha OS...3623e-113     340     55     66GO:0005956; C:protein kinase CK2 complex; IDA:SGD.::GO:0034456; C:UTP-C complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0006356; P:regulation of transcription from RNA polymerase I promoter; IDA:SGD.::GO:0006359; P:regulation of transcription from RNA polymerase III promoter; IDA:SGD.::GO:0006974; P:response to DNA damage stimulus; IDA:SGD.
28Q8SRU0    319   CSK2A_ENCCU Probable casein kinase II subunit...3292e-96     295     48     66
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
29P29618    294   CDKA1_ORYSJ Cyclin-dependent kinase A-1 OS=Or...3008e-38     142     32     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
30P23111    294   CDC2_MAIZE Cell division control protein 2 ho...3043e-37     140     32     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0007067; P:mitosis; IEA:UniProtKB-KW.
31Q38772    294   CDC2A_ANTMA Cell division control protein 2 h...3047e-36     137     32     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
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