Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR054C
Length:
674
Number of sequences:
5887
Description:
YOR054C VHS3 SGDID:S000005580, Chr XV from 429857-427833, Genome Release 64-1-1, reverse complement, Verified ORF, "Negative regulatory subunit of protein phosphatase 1 Ppz1p and also a subunit of the phosphopantothenoylcysteine decarboxylase (PPCDC; Cab3p, Sis2p, Vhs3p) complex, which catalyzes the third step of coenzyme A biosynthesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q08438    674   VHS3_YEAST Phosphopantothenoylcysteine decarb...6740     1366     100     100GO:0071513; C:phosphopantothenoylcysteine decarboxylase complex; IDA:SGD.
GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004864; F:protein phosphatase inhibitor activity; IDA:SGD.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030004; P:cellular monovalent inorganic cation homeostasis; IPI:SGD.::GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-KW.
2P36024    562   SIS2_YEAST Phosphopantothenoylcysteine decarb...770.00000000001     71.2     57     69GO:0005634; C:nucleus; IDA:SGD.::GO:0071513; C:phosphopantothenoylcysteine decarboxylase complex; IDA:SGD.
GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004864; F:protein phosphatase inhibitor activity; IDA:SGD.
GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-KW.::GO:0007346; P:regulation of mitotic cell cycle; IGI:SGD.::GO:0009651; P:response to salt stress; IGI:SGD.
3Q12600    531   SIS2_CANTR Protein SIS2 OS=Candida tropicalis...590.000000000000009     81.3     63     75GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0003824; F:catalytic activity; IEA:InterPro.
4Q9SWE5    209   HAL3A_ARATH Phosphopantothenoylcysteine decar...1354e-33     131     47     67GO:0005829; C:cytosol; IDA:TAIR.
GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IDA:TAIR.
GO:0015937; P:coenzyme A biosynthetic process; TAS:TAIR.::GO:0042538; P:hyperosmotic salinity response; IEP:TAIR.
5P94063    201   HAL3B_ARATH Probable phosphopantothenoylcyste...1322e-32     129     45     69
GO:0010181; F:FMN binding; ISS:TAIR.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IGI:TAIR.
GO:0015937; P:coenzyme A biosynthetic process; IMP:TAIR.::GO:0042538; P:hyperosmotic salinity response; IEP:TAIR.
6P36076    571   CAB3_YEAST Coenzyme A biosynthesis protein 3 ...1330.00000006     59.7     34     49GO:0071513; C:phosphopantothenoylcysteine decarboxylase complex; IDA:SGD.
GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0015937; P:coenzyme A biosynthetic process; IGI:SGD.::GO:0009651; P:response to salt stress; IGI:SGD.
7Q8BZB2    204   COAC_MOUSE Phosphopantothenoylcysteine decarb...641.3     35     30     55
GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-KW.
8Q96CD2    204   COAC_HUMAN Phosphopantothenoylcysteine decarb...530.98     35.4     36     57GO:0005829; C:cytosol; TAS:Reactome.
GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; TAS:Reactome.
GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-KW.::GO:0015939; P:pantothenate metabolic process; TAS:Reactome.
9Q9UTI7    625   TYSY_SCHPO Probable thymidylate synthase OS=S...800.089     39.7     34     50GO:0005829; C:cytosol; IDA:PomBase.
GO:0004799; F:thymidylate synthase activity; ISS:PomBase.
GO:0006231; P:dTMP biosynthetic process; ISS:PomBase.
10Q54Y51    197   COAC_DICDI Putative phosphopantothenoylcystei...1256e-18     87.4     40     60
GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; ISS:dictyBase.
GO:0015937; P:coenzyme A biosynthetic process; ISS:dictyBase.
11P0C6U3    4471   R1A_CVHN1 Replicase polyprotein 1a OS=Human c...980.088     40     37     48GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
12P0C6X2    7182   R1AB_CVHN1 Replicase polyprotein 1ab OS=Human...980.09     40     37     48GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
13P0C6U4    4441   R1A_CVHN2 Replicase polyprotein 1a OS=Human c...860.048     40.8     34     50GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
14P0C6X3    7152   R1AB_CVHN2 Replicase polyprotein 1ab OS=Human...860.049     40.8     34     50GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
15Q54433    179   COAC_STRMU Probable phosphopantothenoylcystei...1370.000000002     61.6     29     52
GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
16P44953    400   COABC_HAEIN Coenzyme A biosynthesis bifunctio...700.00000001     61.2     36     70
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
17P0C6U5    4421   R1A_CVHN5 Replicase polyprotein 1a OS=Human c...860.048     40.8     34     50GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
18P0C6X4    7132   R1AB_CVHN5 Replicase polyprotein 1ab OS=Human...860.049     40.8     34     50GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
19P73881    402   COABC_SYNY3 Coenzyme A biosynthesis bifunctio...630.00000004     59.7     48     67
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
20Q5E8M6    409   COABC_VIBF1 Coenzyme A biosynthesis bifunctio...1040.0000001     58.2     29     63
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
21Q9KVD1    399   COABC_VIBCH Coenzyme A biosynthesis bifunctio...1070.0000002     57.4     32     61
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
22Q58323    403   COABC_METJA Coenzyme A biosynthesis bifunctio...770.0000004     56.2     35     57
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
23Q7MPS9    401   COABC_VIBVY Coenzyme A biosynthesis bifunctio...1050.000001     55.1     27     61
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
24Q8DDX8    401   COABC_VIBVU Coenzyme A biosynthesis bifunctio...1050.000001     55.1     27     61
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
25P0ABQ0    406   COABC_ECOLI Coenzyme A biosynthesis bifunctio...1040.000003     53.9     29     57
GO:0010181; F:FMN binding; IDA:EcoCyc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IDA:EcoCyc.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IDA:EcoCyc.
GO:0015937; P:coenzyme A biosynthetic process; IDA:EcoCyc.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
26P0ABQ1    406   COABC_ECOL6 Coenzyme A biosynthesis bifunctio...1040.000003     53.9     29     57
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
27Q87T89    399   COABC_VIBPA Coenzyme A biosynthesis bifunctio...1040.000009     52.4     27     62
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
28O51752    390   COABC_BORBU Coenzyme A biosynthesis bifunctio...780.00003     50.4     32     64
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
29Q9RC23    194   MRSD_BACSY Mersacidin decarboxylase OS=Bacill...720.0006     45.1     32     57
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0016491; F:oxidoreductase activity; IDA:UniProtKB.
GO:0017000; P:antibiotic biosynthetic process; IDA:UniProtKB.
30O35033    406   COABC_BACSU Probable coenzyme A biosynthesis ...1050.002     45.1     29     57
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
31Q58140    186   Y730_METJA Uncharacterized protein MJ0730 OS=...550.003     43.1     44     62
GO:0003824; F:catalytic activity; IEA:InterPro.
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