UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YOR033C

Length:

702

Number of sequences:

5887

Description:

YOR033C EXO1 SGDID:S000005559, Chr XV from 394524-392416, Genome Release 64-1-1, reverse complement, Verified ORF, "5'-3' exonuclease and flap-endonuclease involved in recombination, double-strand break repair and DNA mismatch repair; member of the Rad2p nuclease family, with conserved N and I nuclease domains"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
151	A8QCH0	378	FEN1_BRUMA Flap endonuclease 1 OS=Brugia mala...	257	0.00000000003	69.7	24	45	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
152	A8XL25	382	FEN1_CAEBR Flap endonuclease 1 OS=Caenorhabdi...	267	0.00000000004	69.3	26	45	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
153	Q2FNC9	333	FEN_METHJ Flap endonuclease 1 OS=Methanospiri...	212	0.00000000004	68.6	26	46
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
154	A7AX58	672	FEN1_BABBO Flap endonuclease 1 OS=Babesia bov...	264	0.00000000004	70.1	28	44	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
155	C5M2X8	374	FEN1_CANTT Flap endonuclease 1 OS=Candida tro...	281	0.00000000004	68.9	25	46	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
156	B8GIA0	333	FEN_METPE Flap endonuclease 1 OS=Methanosphae...	204	0.00000000004	68.6	26	45
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
157	A3CWV2	333	FEN_METMJ Flap endonuclease 1 OS=Methanoculle...	186	0.00000000004	68.6	28	47
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
158	A5E121	384	FEN1_LODEL Flap endonuclease 1 OS=NBRC 1676 /...	283	0.00000000006	68.6	26	45	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
159	B6HEM2	395	FEN1_PENCW Flap endonuclease 1 OS=54-1255) (P...	226	0.00000000006	68.6	25	45	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
160	Q5XIP6	380	FEN1_RAT Flap endonuclease 1 OS=Rattus norveg...	281	0.00000000007	68.2	22	43	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
161	Q5UQW7	473	YL386_MIMIV Putative endonuclease L386 OS=Aca...	259	0.00000000007	68.6	26	42
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:InterPro.
162	P70040	382	FEN1A_XENLA Flap endonuclease 1-A OS=Xenopus ...	297	0.00000000008	68.2	25	43	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0017108; F:5'-flap endonuclease activity; IDA:UniProtKB.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IDA:UniProtKB.::GO:0006260; P:DNA replication; IPI:UniProtKB.
163	P35689	1170	ERCC5_MOUSE DNA repair protein complementing ...	105	0.000002	55.1	36	53	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
									GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
164	Q6BLF4	379	FEN1_DEBHA Flap endonuclease 1 OS=0083 / IGC ...	267	0.00000000009	67.8	27	46	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
165	P07276	1031	RAD2_YEAST DNA repair protein RAD2 OS=Sacchar...	186	0.001	46.2	22	39	GO:0000112; C:nucleotide-excision repair factor 3 complex; IDA:SGD.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.::GO:0000014; F:single-stranded DNA specific endodeoxyribonuclease activity; IDA:SGD.
									GO:0006295; P:nucleotide-excision repair, DNA incision, 3'-to lesion; IMP:SGD.
166	A5DCF5	374	FEN1_PICGU Flap endonuclease 1 OS=1539 / NBRC...	283	0.0000000001	67.8	26	42	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
167	Q8SS91	345	FEN1_ENCCU Flap endonuclease 1 OS=Encephalito...	209	0.0000000001	67.4	28	46	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
168	Q8BMI4	908	GEN_MOUSE Flap endonuclease GEN homolog 1 OS=...	253	0.0000000001	68.6	23	42	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
169	P28715	1186	ERCC5_HUMAN DNA repair protein complementing ...	96	0.00001	52.8	34	50	GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0000405; F:bubble DNA binding; IDA:UniProtKB.::GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.::GO:0004520; F:endodeoxyribonuclease activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
									GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.::GO:0006295; P:nucleotide-excision repair, DNA incision, 3'-to lesion; IDA:UniProtKB.::GO:0010225; P:response to UV-C; IMP:UniProtKB.::GO:0006283; P:transcription-coupled nucleotide-excision repair; IMP:UniProtKB.::GO:0009650; P:UV protection; IGI:MGI.
170	P14629	1196	ERCC5_XENLA DNA repair protein complementing ...	110	0.000003	54.7	32	50	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
									GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
171	A2BMI0	350	FEN_HYPBU Flap endonuclease 1 OS=Hyperthermus...	246	0.0000000003	66.2	26	46
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
172	B7XHS8	358	FEN1_ENTBH Flap endonuclease 1 OS=Enterocytoz...	282	0.0000000003	66.2	26	45	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
173	B1H158	382	FEN1_XENTR Flap endonuclease 1 OS=Xenopus tro...	282	0.0000000003	66.2	24	46	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
174	Q8TIY5	338	FEN_METAC Flap endonuclease 1 OS=C2A). GN=fen...	251	0.0000000003	65.9	23	44
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
175	B9WLQ5	372	FEN1_CANDC Flap endonuclease 1 OS=3949 / NRRL...	317	0.0000000004	65.9	25	44	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
176	C9ZKW4	393	FEN1_TRYB9 Flap endonuclease 1 OS=Trypanosoma...	187	0.0000000004	66.2	26	47	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
177	Q57WW6	393	FEN1_TRYB2 Flap endonuclease 1 OS=Trypanosoma...	187	0.0000000004	66.2	26	47	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
178	P28706	1112	RAD13_SCHPO DNA repair protein rad13 OS=Schiz...	120	0.000002	55.1	31	50	GO:0005634; C:nucleus; IDA:PomBase.
									GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
									GO:0006295; P:nucleotide-excision repair, DNA incision, 3'-to lesion; TAS:PomBase.
179	A4HFE4	395	FEN1_LEIBR Flap endonuclease 1 OS=Leishmania ...	219	0.0000000006	65.5	25	42	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
180	C4YLS2	372	FEN1_CANAW Flap endonuclease 1 OS=Candida alb...	281	0.0000000006	65.1	25	44	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
181	Q4DKQ5	393	FEN1_TRYCC Flap endonuclease 1 OS=Trypanosoma...	294	0.0000000007	65.5	26	45	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.

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