UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YOR027W

Length:

589

Number of sequences:

5887

Description:

YOR027W STI1 SGDID:S000005553, Chr XV from 381053-382822, Genome Release 64-1-1, Verified ORF, "Hsp90 cochaperone, interacts with the Ssa group of the cytosolic Hsp70 chaperones and activates Ssa1p ATPase activity; interacts with Hsp90 chaperones and inhibits their ATPase activity; homolog of mammalian Hop"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
61	Q75Q39	610	TOM70_RAT Mitochondrial import receptor subun...	98	8.1	33.1	30	52	GO:0016021; C:integral to membrane; TAS:RGD.::GO:0005741; C:mitochondrial outer membrane; TAS:RGD.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0015031; P:protein transport; TAS:RGD.
62	Q80ZX8	901	SPAG1_MOUSE Sperm-associated antigen 1 OS=Mus...	126	2.9	34.7	25	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
									GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
63	Q9D4H7	753	LONF3_MOUSE LON peptidase N-terminal domain a...	95	0.004	43.9	31	46
									GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:InterPro.
64	Q96AY4	2481	TTC28_HUMAN Tetratricopeptide repeat protein ...	177	5.8	33.9	19	45
									GO:0005488; F:binding; IEA:InterPro.
65	Q9SIN1	691	TTL3_ARATH Inactive TPR repeat-containing thi...	154	0.63	36.6	29	45
									GO:0005515; F:protein binding; IPI:IntAct.
									GO:0009734; P:auxin mediated signaling pathway; IMP:TAIR.::GO:0009742; P:brassinosteroid mediated signaling pathway; IMP:TAIR.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0010305; P:leaf vascular tissue pattern formation; IMP:TAIR.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
66	Q3ZBR5	292	TTC1_BOVIN Tetratricopeptide repeat protein 1...	110	0.000002	53.1	31	52
									GO:0005488; F:binding; IEA:InterPro.
67	P30416	458	FKBP4_MOUSE Peptidyl-prolyl cis-trans isomera...	200	0.17	38.5	24	43	GO:0044295; C:axonal growth cone; ISS:UniProtKB.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016020; C:membrane; IBA:RefGenome.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:MGI.
									GO:0005524; F:ATP binding; IDA:MGI.::GO:0005528; F:FK506 binding; IBA:RefGenome.::GO:0035259; F:glucocorticoid receptor binding; IDA:MGI.::GO:0005525; F:GTP binding; IDA:MGI.::GO:0031072; F:heat shock protein binding; IDA:MGI.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome.::GO:0051219; F:phosphoprotein binding; IDA:MGI.
									GO:0030521; P:androgen receptor signaling pathway; IMP:MGI.::GO:0007566; P:embryo implantation; IMP:MGI.::GO:0046661; P:male sex differentiation; IMP:MGI.::GO:0031111; P:negative regulation of microtubule polymerization or depolymerization; ISS:UniProtKB.::GO:0010977; P:negative regulation of neuron projection development; ISS:UniProtKB.::GO:0030850; P:prostate gland development; IMP:MGI.::GO:0031503; P:protein complex localization; IDA:MGI.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.::GO:0006463; P:steroid hormone receptor complex assembly; IDA:MGI.
68	Q6ES52	317	TDX_ORYSJ TPR repeat-containing thioredoxin T...	96	0.0000001	57.4	36	57
									GO:0005488; F:binding; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
69	Q5EA11	388	TTC4_BOVIN Tetratricopeptide repeat protein 4...	98	0.000001	54.3	35	52
									GO:0005488; F:binding; IEA:InterPro.
70	Q86DS1	377	F10A2_DROME Hsc70-interacting protein 2 OS=Dr...	226	0.001	45.4	21	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; ISS:UniProtKB.
									GO:0030544; F:Hsp70 protein binding; ISS:UniProtKB.
									GO:0070389; P:chaperone cofactor-dependent protein refolding; ISS:UniProtKB.
71	C4NYP8	377	F10A1_DROME Hsc70-interacting protein 1 OS=Dr...	226	0.001	45.4	21	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; ISS:UniProtKB.
									GO:0030544; F:Hsp70 protein binding; ISS:UniProtKB.
									GO:0070389; P:chaperone cofactor-dependent protein refolding; ISS:UniProtKB.
72	P53804	2025	TTC3_HUMAN E3 ubiquitin-protein ligase TTC3 O...	140	0.008	43.1	26	43	GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
73	P07213	617	TOM70_YEAST Mitochondrial import receptor sub...	85	0.28	37.7	25	51	GO:0031307; C:integral to mitochondrial outer membrane; IDA:SGD.::GO:0005742; C:mitochondrial outer membrane translocase complex; IDA:SGD.
									GO:0030943; F:mitochondrion targeting sequence binding; IMP:SGD.::GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
									GO:0045039; P:protein import into mitochondrial inner membrane; IMP:SGD.::GO:0030150; P:protein import into mitochondrial matrix; IMP:SGD.
74	A6ZRW3	617	TOM70_YEAS7 Mitochondrial import receptor sub...	85	0.28	37.7	25	51	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
									GO:0005488; F:binding; IEA:InterPro.::GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.
75	Q5ZHY5	314	CHIP_CHICK STIP1 homology and U box-containin...	102	0.000004	52.4	29	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
									GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0034450; F:ubiquitin-ubiquitin ligase activity; ISS:UniProtKB.
									GO:0071218; P:cellular response to misfolded protein; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; ISS:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
76	O95801	387	TTC4_HUMAN Tetratricopeptide repeat protein 4...	106	0.0000005	55.8	35	53
									GO:0005488; F:binding; IEA:InterPro.
77	Q8IZP2	240	ST134_HUMAN Putative protein FAM10A4 OS=Homo ...	73	0.004	42.7	33	51
78	Q68F64	927	UN45B_XENLA Protein unc-45 homolog B OS=Xenop...	216	2.8	34.7	26	41	GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
79	Q95LY5	577	TTC12_MACFA Tetratricopeptide repeat protein ...	217	0.014	42	25	47
									GO:0005488; F:binding; IEA:InterPro.
80	Q9MUK5	593	TOC64_PEA Translocon at the outer membrane of...	120	0.14	38.9	33	49	GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0016884; F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.
81	Q9QVC8	458	FKBP4_RAT Peptidyl-prolyl cis-trans isomerase...	46	0.21	38.1	39	54	GO:0044295; C:axonal growth cone; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
									GO:0032767; F:copper-dependent protein binding; IPI:RGD.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.::GO:0048156; F:tau protein binding; IPI:UniProtKB.
									GO:0006825; P:copper ion transport; IMP:RGD.::GO:0031115; P:negative regulation of microtubule polymerization; IMP:RGD.::GO:0010977; P:negative regulation of neuron projection development; ISS:UniProtKB.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.
82	Q9H892	705	TTC12_HUMAN Tetratricopeptide repeat protein ...	155	0.6	37	25	48
									GO:0005488; F:binding; IEA:InterPro.
83	Q6DGE9	934	UN45B_DANRE Protein unc-45 homolog B OS=Danio...	229	0.12	39.3	28	41	GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:ZFIN.
									GO:0005515; F:protein binding; IPI:ZFIN.
									GO:0048738; P:cardiac muscle tissue development; IMP:ZFIN.::GO:0030239; P:myofibril assembly; IMP:ZFIN.::GO:0007519; P:skeletal muscle tissue development; IMP:ZFIN.
84	Q496Y0	759	LONF3_HUMAN LON peptidase N-terminal domain a...	95	0.015	42	31	45
									GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:InterPro.
85	P53043	513	PPT1_YEAST Serine/threonine-protein phosphata...	68	0.17	38.5	34	60	GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:SGD.
									GO:0006470; P:protein dephosphorylation; IDA:SGD.
86	Q9WUD1	304	CHIP_MOUSE STIP1 homology and U box-containin...	103	0.000005	52	31	51	GO:0005737; C:cytoplasm; ISS:HGNC.::GO:0031371; C:ubiquitin conjugating enzyme complex; TAS:HGNC.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
									GO:0030544; F:Hsp70 protein binding; ISS:HGNC.::GO:0051879; F:Hsp90 protein binding; ISS:BHF-UCL.::GO:0030674; F:protein binding, bridging; TAS:HGNC.::GO:0042803; F:protein homodimerization activity; IDA:HGNC.::GO:0046332; F:SMAD binding; ISS:HGNC.::GO:0030911; F:TPR domain binding; ISS:HGNC.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0034450; F:ubiquitin-ubiquitin ligase activity; IDA:MGI.
									GO:0071218; P:cellular response to misfolded protein; IMP:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; IMP:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:HGNC.::GO:0031398; P:positive regulation of protein ubiquitination; ISS:HGNC.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0006457; P:protein folding; TAS:HGNC.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0051604; P:protein maturation; TAS:HGNC.::GO:0031943; P:regulation of glucocorticoid metabolic process; ISS:HGNC.::GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; ISS:HGNC.
87	Q5RAP0	929	UN45A_PONAB Protein unc-45 homolog A OS=Pongo...	81	0.001	45.8	38	56	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
88	Q99L47	371	F10A1_MOUSE Hsc70-interacting protein OS=Mus ...	47	0.04	40	40	55
89	Q9MAH1	699	TTL1_ARATH TPR repeat-containing thioredoxin ...	61	6.9	33.5	33	51
									GO:0005488; F:binding; IEA:InterPro.
									GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0009789; P:positive regulation of abscisic acid mediated signaling pathway; IMP:UniProtKB.::GO:0009651; P:response to salt stress; IMP:UniProtKB.
90	Q99614	292	TTC1_HUMAN Tetratricopeptide repeat protein 1...	110	0.000002	53.5	31	52
									GO:0051082; F:unfolded protein binding; TAS:ProtInc.
									GO:0006457; P:protein folding; TAS:ProtInc.
91	P27124	458	FKBP4_RABIT Peptidyl-prolyl cis-trans isomera...	46	0.43	37	37	54	GO:0044295; C:axonal growth cone; ISS:UniProtKB.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.::GO:0048156; F:tau protein binding; IPI:UniProtKB.
									GO:0031111; P:negative regulation of microtubule polymerization or depolymerization; IDA:UniProtKB.::GO:0010977; P:negative regulation of neuron projection development; IDA:UniProtKB.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.

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