Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOR025W
Length:
447
Number of sequences:
5887
Description:
YOR025W HST3 SGDID:S000005551, Chr XV from 378219-379562, Genome Release 64-1-1, Verified ORF, "Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151Q20481    287   SIR42_CAEEL NAD-dependent protein deacetylase...3070.000003     52.4     25     38
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0040011; P:locomotion; IMP:WormBase.::GO:0006476; P:protein deacetylation; IEA:InterPro.
152F7DKV7    309   SIR5_XENTR NAD-dependent protein deacylase si...2740.000005     52     24     38GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
153Q882K4    281   NPD3_PSESM NAD-dependent protein deacetylase ...3200.000005     51.6     22     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
154Q607X6    255   NPD_METCA NAD-dependent protein deacylase OS=...2980.000005     51.2     24     36GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
155Q5HZN8    309   SIR5A_XENLA NAD-dependent protein deacylase s...2700.000006     51.6     22     37GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
156Q8K2C6    310   SIR5_MOUSE NAD-dependent protein deacylase si...2750.000008     51.2     24     40GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB.
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0036054; F:protein-malonyllysine demalonylase activity; IMP:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; ISS:UniProtKB.
157Q8IE47    273   SIR5_PLAF7 NAD-dependent protein deacylase Si...2790.00001     50.4     23     37
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
158Q7UFQ9    239   NPD_RHOBA NAD-dependent protein deacylase OS=...2500.00001     50.4     25     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
159Q3ZBQ0    310   SIR5_BOVIN NAD-dependent protein deacylase si...2740.00001     50.4     24     39GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB.
GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0006476; P:protein deacetylation; ISS:UniProtKB.
160Q9A2S6    238   NPD_CAUCR NAD-dependent protein deacylase OS=...2100.00002     49.3     26     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
161Q68FX9    310   SIR5_RAT NAD-dependent protein deacylase sirt...3040.00002     50.1     22     39GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB.
GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0006476; P:protein deacetylation; ISS:UniProtKB.
162Q669P6    243   NPD_YERPS NAD-dependent protein deacylase OS=...2680.00002     49.3     26     36GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
163Q8ZFR1    243   NPD_YERPE NAD-dependent protein deacylase OS=...2680.00002     49.3     26     36GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
164Q95Q89    292   SIR24_CAEEL NAD-dependent protein deacetylase...1960.00002     49.7     23     40
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
165Q8IRR5    312   SIR4_DROME NAD-dependent protein deacetylase ...2530.00003     49.7     25     38
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
166Q6MJJ2    235   NPD_BDEBA NAD-dependent protein deacylase OS=...2470.00004     48.5     27     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
167Q6DHI5    305   SIR5_DANRE NAD-dependent protein deacylase si...2740.00004     48.9     23     40GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
168P59941    334   SIR6_MOUSE NAD-dependent protein deacetylase ...3000.00005     48.9     22     38GO:0005724; C:nuclear telomeric heterochromatin; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; ISS:UniProtKB.
GO:0003956; F:NAD(P)+-protein-arginine ADP-ribosyltransferase activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); ISS:UniProtKB.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0006471; P:protein ADP-ribosylation; IDA:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB.
169E1BRE2    309   SIR5_CHICK NAD-dependent protein deacylase si...2700.00005     48.9     24     40
GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
170Q9Y6E7    314   SIR4_HUMAN NAD-dependent protein deacetylase ...2760.00007     48.1     22     42GO:0005759; C:mitochondrial matrix; IDA:UniProtKB.
GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006342; P:chromatin silencing; TAS:ProtInc.::GO:0046676; P:negative regulation of insulin secretion; IMP:UniProtKB.::GO:0006471; P:protein ADP-ribosylation; TAS:BHF-UCL.::GO:0006476; P:protein deacetylation; IEA:InterPro.
171F7EZ75    310   SIR5_MACMU NAD-dependent protein deacylase si...2730.00007     48.1     23     40
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
172Q1JQC6    315   SIR4_BOVIN NAD-dependent protein deacetylase ...2910.0001     47.4     22     41GO:0005759; C:mitochondrial matrix; IDA:UniProtKB.
GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0046676; P:negative regulation of insulin secretion; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro.
173P0A2F2    236   NPD_SALTY NAD-dependent protein deacylase OS=...2700.0001     47     23     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
174P0A2F3    236   NPD_SALTI NAD-dependent protein deacylase OS=...2700.0001     47     23     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
175E2RDZ6    310   SIR5_CANFA NAD-dependent protein deacylase si...2710.0001     47.4     24     39
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
176Q7VX46    274   NPD_BORPE NAD-dependent protein deacetylase O...2640.0001     47     23     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
177Q5R6G3    310   SIR5_PONAB NAD-dependent protein deacylase si...2730.0002     47     22     40GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB.
GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0006476; P:protein deacetylation; ISS:UniProtKB.
178Q7WLE5    274   NPD_BORBR NAD-dependent protein deacetylase O...2640.0002     46.6     23     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
179Q9NXA8    310   SIR5_HUMAN NAD-dependent protein deacylase si...2730.0002     47     22     40GO:0005758; C:mitochondrial intermembrane space; IDA:UniProtKB.::GO:0005759; C:mitochondrial matrix; IDA:UniProtKB.
GO:0003950; F:NAD+ ADP-ribosyltransferase activity; TAS:ProtInc.::GO:0070403; F:NAD+ binding; IDA:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; IDA:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0006342; P:chromatin silencing; TAS:ProtInc.::GO:0006471; P:protein ADP-ribosylation; TAS:ProtInc.::GO:0006476; P:protein deacetylation; IDA:UniProtKB.
180Q584D5    244   SIR5_TRYB2 NAD-dependent protein deacetylase ...2730.0004     45.4     26     38
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
181B8ARK7    484   SIR1_ORYSI NAD-dependent protein deacetylase ...1270.0008     45.4     28     43
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
records
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