rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | Q20481 | 287 | SIR42_CAEEL NAD-dependent protein deacetylase... | 307 | 0.000003 | 52.4 | 25 | 38 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0040011; P:locomotion; IMP:WormBase.::GO:0006476; P:protein deacetylation; IEA:InterPro. | 152 | F7DKV7 | 309 | SIR5_XENTR NAD-dependent protein deacylase si... | 274 | 0.000005 | 52 | 24 | 38 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | | 153 | Q882K4 | 281 | NPD3_PSESM NAD-dependent protein deacetylase ... | 320 | 0.000005 | 51.6 | 22 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 154 | Q607X6 | 255 | NPD_METCA NAD-dependent protein deacylase OS=... | 298 | 0.000005 | 51.2 | 24 | 36 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 155 | Q5HZN8 | 309 | SIR5A_XENLA NAD-dependent protein deacylase s... | 270 | 0.000006 | 51.6 | 22 | 37 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | | 156 | Q8K2C6 | 310 | SIR5_MOUSE NAD-dependent protein deacylase si... | 275 | 0.000008 | 51.2 | 24 | 40 | GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB. | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0036054; F:protein-malonyllysine demalonylase activity; IMP:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; ISS:UniProtKB. | 157 | Q8IE47 | 273 | SIR5_PLAF7 NAD-dependent protein deacylase Si... | 279 | 0.00001 | 50.4 | 23 | 37 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 158 | Q7UFQ9 | 239 | NPD_RHOBA NAD-dependent protein deacylase OS=... | 250 | 0.00001 | 50.4 | 25 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 159 | Q3ZBQ0 | 310 | SIR5_BOVIN NAD-dependent protein deacylase si... | 274 | 0.00001 | 50.4 | 24 | 39 | GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB. | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006476; P:protein deacetylation; ISS:UniProtKB. | 160 | Q9A2S6 | 238 | NPD_CAUCR NAD-dependent protein deacylase OS=... | 210 | 0.00002 | 49.3 | 26 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 161 | Q68FX9 | 310 | SIR5_RAT NAD-dependent protein deacylase sirt... | 304 | 0.00002 | 50.1 | 22 | 39 | GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB. | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006476; P:protein deacetylation; ISS:UniProtKB. | 162 | Q669P6 | 243 | NPD_YERPS NAD-dependent protein deacylase OS=... | 268 | 0.00002 | 49.3 | 26 | 36 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 163 | Q8ZFR1 | 243 | NPD_YERPE NAD-dependent protein deacylase OS=... | 268 | 0.00002 | 49.3 | 26 | 36 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 164 | Q95Q89 | 292 | SIR24_CAEEL NAD-dependent protein deacetylase... | 196 | 0.00002 | 49.7 | 23 | 40 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 165 | Q8IRR5 | 312 | SIR4_DROME NAD-dependent protein deacetylase ... | 253 | 0.00003 | 49.7 | 25 | 38 | | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 166 | Q6MJJ2 | 235 | NPD_BDEBA NAD-dependent protein deacylase OS=... | 247 | 0.00004 | 48.5 | 27 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 167 | Q6DHI5 | 305 | SIR5_DANRE NAD-dependent protein deacylase si... | 274 | 0.00004 | 48.9 | 23 | 40 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | | 168 | P59941 | 334 | SIR6_MOUSE NAD-dependent protein deacetylase ... | 300 | 0.00005 | 48.9 | 22 | 38 | GO:0005724; C:nuclear telomeric heterochromatin; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0003956; F:NAD(P)+-protein-arginine ADP-ribosyltransferase activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); ISS:UniProtKB.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006471; P:protein ADP-ribosylation; IDA:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB. | 169 | E1BRE2 | 309 | SIR5_CHICK NAD-dependent protein deacylase si... | 270 | 0.00005 | 48.9 | 24 | 40 | | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | | 170 | Q9Y6E7 | 314 | SIR4_HUMAN NAD-dependent protein deacetylase ... | 276 | 0.00007 | 48.1 | 22 | 42 | GO:0005759; C:mitochondrial matrix; IDA:UniProtKB. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006342; P:chromatin silencing; TAS:ProtInc.::GO:0046676; P:negative regulation of insulin secretion; IMP:UniProtKB.::GO:0006471; P:protein ADP-ribosylation; TAS:BHF-UCL.::GO:0006476; P:protein deacetylation; IEA:InterPro. | 171 | F7EZ75 | 310 | SIR5_MACMU NAD-dependent protein deacylase si... | 273 | 0.00007 | 48.1 | 23 | 40 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 172 | Q1JQC6 | 315 | SIR4_BOVIN NAD-dependent protein deacetylase ... | 291 | 0.0001 | 47.4 | 22 | 41 | GO:0005759; C:mitochondrial matrix; IDA:UniProtKB. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0046676; P:negative regulation of insulin secretion; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro. | 173 | P0A2F2 | 236 | NPD_SALTY NAD-dependent protein deacylase OS=... | 270 | 0.0001 | 47 | 23 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 174 | P0A2F3 | 236 | NPD_SALTI NAD-dependent protein deacylase OS=... | 270 | 0.0001 | 47 | 23 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 175 | E2RDZ6 | 310 | SIR5_CANFA NAD-dependent protein deacylase si... | 271 | 0.0001 | 47.4 | 24 | 39 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 176 | Q7VX46 | 274 | NPD_BORPE NAD-dependent protein deacetylase O... | 264 | 0.0001 | 47 | 23 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 177 | Q5R6G3 | 310 | SIR5_PONAB NAD-dependent protein deacylase si... | 273 | 0.0002 | 47 | 22 | 40 | GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB. | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006476; P:protein deacetylation; ISS:UniProtKB. | 178 | Q7WLE5 | 274 | NPD_BORBR NAD-dependent protein deacetylase O... | 264 | 0.0002 | 46.6 | 23 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 179 | Q9NXA8 | 310 | SIR5_HUMAN NAD-dependent protein deacylase si... | 273 | 0.0002 | 47 | 22 | 40 | GO:0005758; C:mitochondrial intermembrane space; IDA:UniProtKB.::GO:0005759; C:mitochondrial matrix; IDA:UniProtKB. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; TAS:ProtInc.::GO:0070403; F:NAD+ binding; IDA:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; IDA:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0006342; P:chromatin silencing; TAS:ProtInc.::GO:0006471; P:protein ADP-ribosylation; TAS:ProtInc.::GO:0006476; P:protein deacetylation; IDA:UniProtKB. | 180 | Q584D5 | 244 | SIR5_TRYB2 NAD-dependent protein deacetylase ... | 273 | 0.0004 | 45.4 | 26 | 38 | | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 181 | B8ARK7 | 484 | SIR1_ORYSI NAD-dependent protein deacetylase ... | 127 | 0.0008 | 45.4 | 28 | 43 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. |