| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | P23916 | 662 | PRCA_ANAVT Calcium-dependent protease OS=Anab... | 277 | 0.00000007 | 58.5 | 26 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 182 | Q59149 | 662 | PRCA_NOSS1 Calcium-dependent protease OS=Nost... | 277 | 0.0000001 | 57.8 | 26 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 183 | P29141 | 806 | SUBV_BACSU Minor extracellular protease vpr O... | 70 | 0.073 | 39.3 | 34 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 184 | P16397 | 1433 | SUBF_BACSU Bacillopeptidase F OS=Bacillus sub... | 251 | 0.0000002 | 57.8 | 26 | 39 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004180; F:carboxypeptidase activity; IEA:InterPro.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 185 | Q28193 | 797 | FURIN_BOVIN Furin OS=Bos taurus (Bovine). GN=... | 195 | 0.000004 | 53.1 | 25 | 42 | GO:0005615; C:extracellular space; ISS:RefGenome.::GO:0005794; C:Golgi apparatus; ISS:RefGenome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 186 | P42781 | 976 | XPR6_YARLI Dibasic-processing endoprotease OS... | 345 | 0.000009 | 52 | 24 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 187 | P23188 | 793 | FURIN_MOUSE Furin OS=Mus musculus (Mouse). GN... | 310 | 0.00001 | 51.6 | 23 | 41 | GO:0005769; C:early endosome; TAS:MGI.::GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0016021; C:integral to membrane; TAS:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0012510; C:trans-Golgi network transport vesicle membrane; TAS:MGI. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 188 | Q9NJ15 | 1696 | PCSK5_BRACL Proprotein convertase subtilisin/... | 313 | 0.00001 | 51.6 | 25 | 39 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 189 | P23377 | 793 | FURIN_RAT Furin OS=Rattus norvegicus (Rat). G... | 162 | 0.00002 | 50.8 | 27 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IDA:RGD.::GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0031985; C:Golgi cisterna; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IMP:RGD. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IMP:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 190 | P29121 | 655 | PCSK4_MOUSE Proprotein convertase subtilisin/... | 311 | 0.00002 | 50.4 | 24 | 42 | GO:0002080; C:acrosomal membrane; IDA:MGI.::GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome. | | | | | | | | | | GO:0007340; P:acrosome reaction; IMP:MGI.::GO:0007339; P:binding of sperm to zona pellucida; IMP:MGI.::GO:0006508; P:proteolysis; IBA:RefGenome.::GO:0048240; P:sperm capacitation; IMP:MGI. | 191 | Q14703 | 1052 | MBTP1_HUMAN Membrane-bound transcription fact... | 238 | 0.00003 | 50.4 | 27 | 38 | GO:0005788; C:endoplasmic reticulum lumen; TAS:ProtInc.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome. | | | | | | | | | | GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IBA:RefGenome. | 192 | P09958 | 794 | FURIN_HUMAN Furin OS=Homo sapiens (Human). GN... | 162 | 0.00003 | 50.1 | 26 | 43 | GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0005796; C:Golgi lumen; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045121; C:membrane raft; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005802; C:trans-Golgi network; IDA:BHF-UCL.::GO:0030140; C:trans-Golgi network transport vesicle; IDA:MGI. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0048406; F:nerve growth factor binding; IDA:BHF-UCL.::GO:0042277; F:peptide binding; IDA:BHF-UCL.::GO:0002020; F:protease binding; IPI:BHF-UCL.::GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.::GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:BHF-UCL. | | | | | | | | | | GO:0008283; P:cell proliferation; IMP:BHF-UCL.::GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.::GO:0032804; P:negative regulation of low-density lipoprotein particle receptor catabolic process; IDA:HGNC.::GO:0032911; P:negative regulation of transforming growth factor beta1 production; IMP:BHF-UCL.::GO:0032455; P:nerve growth factor processing; TAS:Reactome.::GO:0032902; P:nerve growth factor production; IDA:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0043043; P:peptide biosynthetic process; IDA:BHF-UCL.::GO:0017187; P:peptidyl-glutamic acid carboxylation; TAS:Reactome.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IC:BHF-UCL.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0006508; P:proteolysis; TAS:Reactome.::GO:0032940; P:secretion by cell; IDA:BHF-UCL.::GO:0006465; P:signal peptide processing; IDA:HGNC.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.::GO:0019067; P:viral assembly, maturation, egress, and release; IEP:BHF-UCL. | 193 | Q9Z2A8 | 1052 | MBTP1_CRIGR Membrane-bound transcription fact... | 420 | 0.00006 | 49.7 | 24 | 36 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 194 | P85156 | 40 | ASE1_ACRSP Subtilisin-like serine protease AS... | 43 | 0.00006 | 45.4 | 47 | 65 | | | | | | | | | | | GO:0016504; F:peptidase activator activity; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 195 | Q78EH2 | 678 | PCSK4_RAT Proprotein convertase subtilisin/ke... | 311 | 0.00008 | 48.9 | 24 | 42 | | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome. | | | | | | | | | | GO:0006508; P:proteolysis; IBA:RefGenome. | 196 | Q9WTZ3 | 1052 | MBTP1_RAT Membrane-bound transcription factor... | 420 | 0.0001 | 48.5 | 24 | 36 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IDA:RGD. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IBA:RefGenome. | 197 | Q9WTZ2 | 1052 | MBTP1_MOUSE Membrane-bound transcription fact... | 240 | 0.0002 | 48.1 | 26 | 39 | GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IDA:MGI. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IBA:RefGenome.::GO:0042990; P:regulation of transcription factor import into nucleus; IDA:MGI. | 198 | P29146 | 793 | NECA_HYDVU PC3-like endoprotease variant A OS... | 265 | 0.0002 | 47.8 | 27 | 38 | | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 199 | P29145 | 710 | NECB_HYDVU PC3-like endoprotease variant B OS... | 265 | 0.0002 | 47.4 | 27 | 38 | | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 200 | Q9RYM8 | 728 | SUB2_DEIRA Probable subtilase-type serine pro... | 288 | 0.0003 | 47 | 24 | 39 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 201 | P51559 | 943 | BLI4_CAEEL Endoprotease bli-4 OS=Caenorhabdit... | 251 | 0.0007 | 45.8 | 25 | 41 | GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; NAS:UniProtKB. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 202 | P13134 | 814 | KEX2_YEAST Kexin OS=Saccharomyces cerevisiae ... | 276 | 0.0009 | 45.4 | 26 | 38 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005802; C:trans-Golgi network; IDA:SGD. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IDA:SGD. | | | | | | | | | | GO:0007323; P:peptide pheromone maturation; IMP:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 203 | P63239 | 753 | NEC1_MOUSE Neuroendocrine convertase 1 OS=Mus... | 170 | 0.001 | 45.1 | 27 | 41 | GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IBA:RefGenome.::GO:0030141; C:secretory granule; TAS:Reactome.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0043043; P:peptide biosynthetic process; IDA:BHF-UCL.::GO:0016486; P:peptide hormone processing; IDA:BHF-UCL.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 204 | P63240 | 753 | NEC1_MUSCO Neuroendocrine convertase 1 OS=Mus... | 170 | 0.001 | 45.1 | 27 | 41 | GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 205 | Q6UW60 | 755 | PCSK4_HUMAN Proprotein convertase subtilisin/... | 154 | 0.001 | 45.1 | 26 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome. | | | | | | | | | | GO:0006508; P:proteolysis; IBA:RefGenome. | 206 | Q63415 | 937 | PCSK6_RAT Proprotein convertase subtilisin/ke... | 327 | 0.001 | 45.1 | 21 | 40 | GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0005794; C:Golgi apparatus; IBA:RefGenome. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome. | | | | | | | | | | GO:0016486; P:peptide hormone processing; IEP:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 207 | P30432 | 1679 | FUR2_DROME Furin-like protease 2 OS=Drosophil... | 96 | 0.002 | 44.7 | 35 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IDA:FlyBase.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 208 | P29122 | 969 | PCSK6_HUMAN Proprotein convertase subtilisin/... | 315 | 0.003 | 43.9 | 23 | 41 | GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0031012; C:extracellular matrix; IDA:BHF-UCL.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005796; C:Golgi lumen; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005625; C:soluble fraction; IDA:BHF-UCL. | | | | | | | | | | GO:0043499; F:eukaryotic cell surface binding; IDA:BHF-UCL.::GO:0008201; F:heparin binding; IDA:BHF-UCL.::GO:0048406; F:nerve growth factor binding; IDA:BHF-UCL.::GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0009100; P:glycoprotein metabolic process; IDA:BHF-UCL.::GO:0032455; P:nerve growth factor processing; TAS:Reactome.::GO:0032902; P:nerve growth factor production; IDA:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0030510; P:regulation of BMP signaling pathway; TAS:BHF-UCL.::GO:0032940; P:secretion by cell; IDA:BHF-UCL. | 209 | P41413 | 1809 | PCSK5_RAT Proprotein convertase subtilisin/ke... | 320 | 0.003 | 43.9 | 24 | 43 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0005794; C:Golgi apparatus; IBA:RefGenome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome. | | | | | | | | | | GO:0007565; P:female pregnancy; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 210 | Q04592 | 1877 | PCSK5_MOUSE Proprotein convertase subtilisin/... | 320 | 0.003 | 43.9 | 24 | 43 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030141; C:secretory granule; IDA:MGI. | | | | | | | | | | GO:0042277; F:peptide binding; IDA:BHF-UCL.::GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IMP:BHF-UCL.::GO:0042089; P:cytokine biosynthetic process; IDA:BHF-UCL.::GO:0007566; P:embryo implantation; IMP:BHF-UCL.::GO:0048566; P:embryonic digestive tract development; IMP:BHF-UCL.::GO:0048706; P:embryonic skeletal system development; IMP:BHF-UCL.::GO:0007507; P:heart development; IMP:BHF-UCL.::GO:0001822; P:kidney development; IMP:BHF-UCL.::GO:0035108; P:limb morphogenesis; IMP:BHF-UCL.::GO:0043043; P:peptide biosynthetic process; IDA:BHF-UCL.::GO:0016486; P:peptide hormone processing; IDA:BHF-UCL.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0030323; P:respiratory tube development; IMP:BHF-UCL.::GO:0019067; P:viral assembly, maturation, egress, and release; IDA:BHF-UCL. | 211 | P29119 | 783 | FURI1_XENLA Furin-1 OS=Xenopus laevis (Africa... | 156 | 0.005 | 43.1 | 23 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
