Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL133W
Length:
121
Number of sequences:
5887
Description:
YOL133W HRT1 SGDID:S000005493, Chr XV from 70325-70690, Genome Release 64-1-1, Verified ORF, "RING finger containing subunit of Skp1-Cullin-F-box ubiquitin protein ligases (SCF); required for Gic2p, Far1p, Sic1p and Cln2p degradation; may tether Cdc34p (a ubiquitin conjugating enzyme or E2) and Cdc53p (a cullin) subunits of SCF"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q08273    121   RBX1_YEAST RING-box protein HRT1 OS=Saccharom...1213e-85     251     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:SGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:SGD.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.
2Q9W5E1    108   RBX1A_DROME RING-box protein 1A OS=Drosophila...1139e-43     142     58     70GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:FlyBase.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0008283; P:cell proliferation; IMP:FlyBase.::GO:0019915; P:lipid storage; IDA:FlyBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IMP:FlyBase.::GO:0007224; P:smoothened signaling pathway; NAS:UniProtKB.
3Q8QG64    108   RBX1_SALSA RING-box protein 1 OS=Salmo salar ...1133e-42     140     58     67GO:0031463; C:Cul3-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0019788; F:NEDD8 ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0045116; P:protein neddylation; ISS:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
4Q54K33    104   RBX1_DICDI RING-box protein 1 OS=Dictyosteliu...1048e-42     139     57     73GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
5P62878    108   RBX1_MOUSE E3 ubiquitin-protein ligase RBX1 O...1141e-41     139     56     65GO:0005680; C:anaphase-promoting complex; TAS:UniProtKB.::GO:0031463; C:Cul3-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0008190; F:eukaryotic initiation factor 4E binding; TAS:UniProtKB.::GO:0019788; F:NEDD8 ligase activity; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0045116; P:protein neddylation; ISS:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
6P62877    108   RBX1_HUMAN E3 ubiquitin-protein ligase RBX1 O...1141e-41     139     56     65GO:0031462; C:Cul2-RING ubiquitin ligase complex; IDA:UniProtKB.::GO:0031463; C:Cul3-RING ubiquitin ligase complex; IDA:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; IDA:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; IDA:UniProtKB.::GO:0031466; C:Cul5-RING ubiquitin ligase complex; IDA:UniProtKB.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0019788; F:NEDD8 ligase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.::GO:0045116; P:protein neddylation; IDA:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.
7Q940X7    118   RBX1A_ARATH RING-box protein 1a OS=Arabidopsi...912e-41     139     66     76GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; IPI:TAIR.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016567; P:protein ubiquitination; TAS:TAIR.::GO:0009733; P:response to auxin stimulus; IMP:TAIR.
8Q23457    110   RBX1_CAEEL RING-box protein 1 OS=Caenorhabdit...976e-41     137     61     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008595; P:anterior/posterior axis specification, embryo; IMP:WormBase.::GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0007138; P:meiotic anaphase II; IMP:WormBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0035046; P:pronuclear migration; IMP:WormBase.::GO:0051759; P:sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation; IMP:WormBase.
9O13959    107   RBX1_SCHPO RING-box protein pip1 OS=Schizosac...1019e-40     134     58     68GO:0031465; C:Cul4B-RING ubiquitin ligase complex; TAS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:PomBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10Q9M2B0    115   RBX1B_ARATH RING-box protein 1b OS=Arabidopsi...895e-38     130     63     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
11Q9NHX0    122   RBX1B_DROME RING-box protein 1B OS=Drosophila...1106e-36     125     54     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IGI:FlyBase.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0019915; P:lipid storage; IDA:FlyBase.::GO:0030317; P:sperm motility; IMP:FlyBase.
12Q9UBF6    113   RBX2_HUMAN RING-box protein 2 OS=Homo sapiens...1115e-24     94.4     41     58GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0005507; F:copper ion binding; TAS:ProtInc.::GO:0019788; F:NEDD8 ligase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0008631; P:induction of apoptosis by oxidative stress; TAS:ProtInc.::GO:0045116; P:protein neddylation; IDA:UniProtKB.::GO:0051775; P:response to redox state; TAS:ProtInc.
13Q9WTZ1    113   RBX2_MOUSE RING-box protein 2 OS=Mus musculus...894e-23     92     46     63GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0019788; F:NEDD8 ligase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:MGI.::GO:0006916; P:anti-apoptosis; IDA:MGI.::GO:0008637; P:apoptotic mitochondrial changes; IDA:MGI.::GO:0008631; P:induction of apoptosis by oxidative stress; IDA:MGI.::GO:0045116; P:protein neddylation; ISS:UniProtKB.
14Q9M9L0    84   APC11_ARATH Anaphase-promoting complex subuni...860.0000000000002     65.9     38     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
15Q54L48    87   APC11_DICDI Anaphase-promoting complex subuni...790.00000000001     60.8     37     53GO:0005680; C:anaphase-promoting complex; ISS:dictyBase.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:dictyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:dictyBase.
16Q3ZCF6    84   APC11_BOVIN Anaphase-promoting complex subuni...860.00000000006     58.9     36     51GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.
17Q9UT86    94   APC11_SCHPO Anaphase-promoting complex subuni...880.0000000001     58.5     38     53GO:0005680; C:anaphase-promoting complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IC:PomBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008054; P:cyclin catabolic process; IC:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IC:PomBase.
18Q9CPX9    84   APC11_MOUSE Anaphase-promoting complex subuni...860.0000000002     57.8     35     51GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.
19Q5R8A2    84   APC11_PONAB Anaphase-promoting complex subuni...860.0000000002     57.4     35     51GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.
20Q9NYG5    84   APC11_HUMAN Anaphase-promoting complex subuni...860.0000000002     57.4     35     51GO:0005680; C:anaphase-promoting complex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; TAS:UniProtKB.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
21Q5UQ40    1297   UBC4_MIMIV Probable bifunctional E2/E3 enzyme...640.0000000005     60.5     44     64GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
22Q9LF64    362   ATL52_ARATH RING-H2 finger protein ATL52 OS=A...750.00002     45.8     35     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
23Q12157    165   APC11_YEAST Anaphase-promoting complex subuni...690.00003     43.9     33     49GO:0005680; C:anaphase-promoting complex; IDA:SGD.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IMP:SGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
24Q9LZV8    159   ATL74_ARATH RING-H2 finger protein ATL74 OS=A...780.00005     43.5     31     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
25Q7X843    349   ATL48_ARATH RING-H2 finger protein ATL48 OS=A...560.0001     43.5     38     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
26O22755    185   ATL44_ARATH RING-H2 finger protein ATL44 OS=A...490.0003     41.6     37     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
27Q9SRQ8    356   ATL51_ARATH RING-H2 finger protein ATL51 OS=A...750.0005     41.6     31     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0080167; P:response to karrikin; IEP:TAIR.
28Q9LX93    301   ATL55_ARATH E3 ubiquitin-protein ligase RING1...850.0006     41.2     29     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0043068; P:positive regulation of programmed cell death; IMP:TAIR.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0009617; P:response to bacterium; IEP:UniProtKB.::GO:0010200; P:response to chitin; IEP:TAIR.::GO:0002238; P:response to molecule of fungal origin; IEP:UniProtKB.
29Q9SG96    181   ATL72_ARATH RING-H2 finger protein ATL72 OS=A...390.002     39.3     41     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
30Q9ZT49    200   ATL45_ARATH RING-H2 finger protein ATL45 OS=A...470.002     39.3     36     62GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0010200; P:response to chitin; IEP:TAIR.
31Q9FL07    376   ATL46_ARATH RING-H2 finger protein ATL46 OS=A...230.002     39.7     52     83GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
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