Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL122C
Length:
575
Number of sequences:
5887
Description:
YOL122C SMF1 SGDID:S000005482, Chr XV from 91419-89692, Genome Release 64-1-1, reverse complement, Verified ORF, "Divalent metal ion transporter with a broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q97TN5    431   MNTH_CLOAB Probable manganese transport prote...4566e-52     189     31     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
62P49282    568   NRAM2_MOUSE Natural resistance-associated mac...4301e-51     191     33     50GO:0005903; C:brush border; IDA:MGI.::GO:0009986; C:cell surface; IDA:MGI.::GO:0005769; C:early endosome; IDA:MGI.::GO:0012505; C:endomembrane system; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005887; C:integral to plasma membrane; IDA:MGI.::GO:0055037; C:recycling endosome; IDA:MGI.
GO:0015087; F:cobalt ion transmembrane transporter activity; IDA:MGI.::GO:0015093; F:ferrous iron transmembrane transporter activity; IDA:MGI.::GO:0015078; F:hydrogen ion transmembrane transporter activity; IDA:MGI.
GO:0048813; P:dendrite morphogenesis; IMP:MGI.::GO:0048821; P:erythrocyte development; IMP:MGI.::GO:0070627; P:ferrous iron import; IDA:MGI.::GO:0006783; P:heme biosynthetic process; IMP:MGI.::GO:0007611; P:learning or memory; IMP:MGI.::GO:0060586; P:multicellular organismal iron ion homeostasis; IMP:MGI.
63O54902    568   NRAM2_RAT Natural resistance-associated macro...4311e-51     191     32     50GO:0031902; C:late endosome membrane; IDA:RGD.::GO:0005765; C:lysosomal membrane; IDA:RGD.
GO:0046870; F:cadmium ion binding; IDA:RGD.::GO:0015086; F:cadmium ion transmembrane transporter activity; IDA:RGD.::GO:0050897; F:cobalt ion binding; IDA:RGD.::GO:0015087; F:cobalt ion transmembrane transporter activity; IDA:RGD.::GO:0005507; F:copper ion binding; IDA:RGD.::GO:0005375; F:copper ion transmembrane transporter activity; IDA:RGD.::GO:0015093; F:ferrous iron transmembrane transporter activity; IMP:RGD.::GO:0005506; F:iron ion binding; IDA:RGD.::GO:0015094; F:lead ion transmembrane transporter activity; IDA:RGD.::GO:0030145; F:manganese ion binding; IDA:RGD.::GO:0005384; F:manganese ion transmembrane transporter activity; IDA:RGD.::GO:0016151; F:nickel cation binding; IDA:RGD.::GO:0015099; F:nickel cation transmembrane transporter activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IDA:RGD.
GO:0071456; P:cellular response to hypoxia; IEP:RGD.::GO:0071281; P:cellular response to iron ion; IEP:RGD.::GO:0071356; P:cellular response to tumor necrosis factor; IEP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0010288; P:response to lead ion; IEP:RGD.::GO:0010042; P:response to manganese ion; IMP:RGD.
64A5G348    433   MNTH_ACICJ Probable manganese transport prote...4424e-51     187     30     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
65Q9RPF2    438   MNTH2_PSEAE Manganese transport protein MntH2...4213e-50     184     36     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
66Q0BW85    444   MNTH_GRABC Probable manganese transport prote...4144e-49     181     30     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
67Q9SNV9    509   NRAM3_ARATH Metal transporter Nramp3 OS=Arabi...4286e-49     182     31     48GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005215; F:transporter activity; IEA:InterPro.
GO:0042742; P:defense response to bacterium; IMP:TAIR.::GO:0055072; P:iron ion homeostasis; IMP:TAIR.::GO:0006828; P:manganese ion transport; IMP:TAIR.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IGI:TAIR.::GO:0010043; P:response to zinc ion; IEP:TAIR.
68O77741    538   NRAM1_PIG Natural resistance-associated macro...4441e-48     182     31     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005215; F:transporter activity; IEA:InterPro.
GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.::GO:0000165; P:MAPK cascade; IDA:MGI.::GO:0032496; P:response to lipopolysaccharide; IDA:MGI.
69Q9C6B2    530   NRAM2_ARATH Metal transporter Nramp2 OS=Arabi...4295e-48     180     30     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005215; F:transporter activity; IEA:InterPro.
GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
70P49279    550   NRAM1_HUMAN Natural resistance-associated mac...4666e-48     180     29     48GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0031902; C:late endosome membrane; TAS:Reactome.::GO:0005764; C:lysosome; ISS:BHF-UCL.::GO:0030670; C:phagocytic vesicle membrane; IDA:BHF-UCL.::GO:0070821; C:tertiary granule membrane; IDA:BHF-UCL.
GO:0005384; F:manganese ion transmembrane transporter activity; ISS:BHF-UCL.::GO:0051139; F:metal ion:hydrogen antiporter activity; IGI:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
GO:0032147; P:activation of protein kinase activity; ISS:BHF-UCL.::GO:0048002; P:antigen processing and presentation of peptide antigen; ISS:BHF-UCL.::GO:0070574; P:cadmium ion transmembrane transport; IGI:BHF-UCL.::GO:0006876; P:cellular cadmium ion homeostasis; IGI:BHF-UCL.::GO:0006879; P:cellular iron ion homeostasis; IMP:BHF-UCL.::GO:0050829; P:defense response to Gram-negative bacterium; ISS:BHF-UCL.::GO:0042832; P:defense response to protozoan; ISS:BHF-UCL.::GO:0070839; P:divalent metal ion export; ISS:BHF-UCL.::GO:0006954; P:inflammatory response; ISS:BHF-UCL.::GO:0032623; P:interleukin-2 production; ISS:BHF-UCL.::GO:0032632; P:interleukin-3 production; ISS:BHF-UCL.::GO:0006826; P:iron ion transport; IMP:BHF-UCL.::GO:0043091; P:L-arginine import; ISS:BHF-UCL.::GO:0042116; P:macrophage activation; ISS:BHF-UCL.::GO:0045342; P:MHC class II biosynthetic process; ISS:BHF-UCL.::GO:0048255; P:mRNA stabilization; ISS:BHF-UCL.::GO:0060586; P:multicellular organismal iron ion homeostasis; ISS:BHF-UCL.::GO:0001818; P:negative regulation of cytokine production; ISS:BHF-UCL.::GO:0015707; P:nitrite transport; ISS:BHF-UCL.::GO:0006909; P:phagocytosis; ISS:BHF-UCL.::GO:0002606; P:positive regulation of dendritic cell antigen processing and presentation; ISS:BHF-UCL.::GO:0032729; P:positive regulation of interferon-gamma production; ISS:BHF-UCL.::GO:0050766; P:positive regulation of phagocytosis; ISS:BHF-UCL.::GO:0002827; P:positive regulation of T-helper 1 type immune response; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0045730; P:respiratory burst; ISS:BHF-UCL.::GO:0034341; P:response to interferon-gamma; ISS:BHF-UCL.::GO:0032496; P:response to lipopolysaccharide; ISS:BHF-UCL.::GO:0002369; P:T cell cytokine production; ISS:BHF-UCL.::GO:0002309; P:T cell proliferation involved in immune response; ISS:BHF-UCL.::GO:0007035; P:vacuolar acidification; ISS:BHF-UCL.::GO:0042060; P:wound healing; ISS:BHF-UCL.
71Q9FN18    512   NRAM4_ARATH Metal transporter Nramp4 OS=Arabi...4302e-47     178     30     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005215; F:transporter activity; IEA:InterPro.
GO:0006879; P:cellular iron ion homeostasis; IGI:TAIR.::GO:0042742; P:defense response to bacterium; IMP:TAIR.::GO:0006828; P:manganese ion transport; IMP:TAIR.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IGI:TAIR.::GO:0010039; P:response to iron ion; IEP:TAIR.::GO:0009624; P:response to nematode; IEP:TAIR.
72B1JFZ6    409   MNTH_YERPY Probable manganese transport prote...4383e-46     172     30     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
73Q668N2    409   MNTH_YERPS Probable manganese transport prote...4383e-46     172     30     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
74A4TMF6    409   MNTH_YERPP Probable manganese transport prote...4383e-46     172     30     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
75Q1CJV0    409   MNTH_YERPN Probable manganese transport prote...4383e-46     172     30     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
76Q8ZCK2    409   MNTH_YERPE Probable manganese transport prote...4383e-46     172     30     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
77B2K911    409   MNTH_YERPB Probable manganese transport prote...4383e-46     172     30     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
78Q1C5Y6    409   MNTH_YERPA Probable manganese transport prote...4383e-46     172     30     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
79A7FGC8    409   MNTH_YERP3 Probable manganese transport prote...4383e-46     172     30     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
80P49281    568   NRAM2_HUMAN Natural resistance-associated mac...4315e-46     175     32     50GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0045178; C:basal part of cell; IDA:UniProtKB.::GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0031410; C:cytoplasmic vesicle; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0005770; C:late endosome; IDA:UniProtKB.::GO:0031902; C:late endosome membrane; IDA:BHF-UCL.::GO:0005765; C:lysosomal membrane; IDA:BHF-UCL.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0070826; C:paraferritin complex; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0055037; C:recycling endosome; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB.
GO:0015086; F:cadmium ion transmembrane transporter activity; IDA:BHF-UCL.::GO:0015087; F:cobalt ion transmembrane transporter activity; IDA:UniProtKB.::GO:0005375; F:copper ion transmembrane transporter activity; IDA:BHF-UCL.::GO:0015093; F:ferrous iron transmembrane transporter activity; IDA:BHF-UCL.::GO:0015094; F:lead ion transmembrane transporter activity; IDA:BHF-UCL.::GO:0005384; F:manganese ion transmembrane transporter activity; IDA:BHF-UCL.::GO:0015099; F:nickel cation transmembrane transporter activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0015295; F:solute:hydrogen symporter activity; IDA:UniProtKB.::GO:0015100; F:vanadium ion transmembrane transporter activity; IDA:UniProtKB.::GO:0005385; F:zinc ion transmembrane transporter activity; IDA:UniProtKB.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.::GO:0034599; P:cellular response to oxidative stress; IDA:UniProtKB.::GO:0003032; P:detection of oxygen; IEP:UniProtKB.::GO:0070627; P:ferrous iron import; IDA:UniProtKB.::GO:0060586; P:multicellular organismal iron ion homeostasis; IMP:BHF-UCL.::GO:0001666; P:response to hypoxia; IEP:UniProtKB.::GO:0010039; P:response to iron ion; IEP:UniProtKB.
81Q0T2A8    412   MNTH_SHIF8 Manganese transport protein MntH O...4386e-46     172     29     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
82P51027    555   NRAM1_CHICK Natural resistance-associated mac...4457e-46     174     30     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IMP:BHF-UCL.
GO:0051139; F:metal ion:hydrogen antiporter activity; IGI:BHF-UCL.::GO:0046915; F:transition metal ion transmembrane transporter activity; IGI:BHF-UCL.
GO:0070574; P:cadmium ion transmembrane transport; IGI:BHF-UCL.::GO:0006876; P:cellular cadmium ion homeostasis; IGI:BHF-UCL.::GO:0070839; P:divalent metal ion export; ISS:BHF-UCL.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
83Q1QZ83    431   MNTH_CHRSD Probable manganese transport prote...4528e-46     172     31     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
84Q9SN36    530   NRAM5_ARATH Metal transporter Nramp5 OS=Arabi...4471e-45     173     30     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005215; F:transporter activity; IEA:InterPro.
GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
85A4WD10    412   MNTH_ENT38 Probable manganese transport prote...4202e-45     170     30     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
86A7MP48    412   MNTH_CROS8 Probable manganese transport prote...4374e-45     169     29     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
87A1JLC3    409   MNTH_YERE8 Probable manganese transport prote...4159e-45     168     29     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
88Q9XT74    547   NRAM1_CANFA Natural resistance-associated mac...4949e-45     171     29     46GO:0016021; C:integral to membrane; NAS:UniProtKB.
GO:0005384; F:manganese ion transmembrane transporter activity; NAS:UniProtKB.
89Q2QN30    541   NRAM6_ORYSJ Metal transporter Nramp6 OS=Oryza...4261e-44     170     29     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005215; F:transporter activity; IEA:InterPro.
GO:0006811; P:ion transport; IEA:UniProtKB-KW.
90C6D9J9    412   MNTH_PECCP Probable manganese transport prote...4193e-44     167     29     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
91P49280    548   NRAM1_SHEEP Natural resistance-associated mac...4643e-44     169     29     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005215; F:transporter activity; IEA:InterPro.
GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
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