Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL115W
Length:
584
Number of sequences:
5887
Description:
YOL115W PAP2 SGDID:S000005475, Chr XV from 101475-103229, Genome Release 64-1-1, Verified ORF, "Non-canonical poly(A) polymerase, involved in nuclear RNA degradation as a component of the TRAMP complex; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; overlapping but non-redundant functions with Trf5p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q9VYS4    1373   GLD2B_DROME Poly(A) RNA polymerase gld-2 homo...1200.001     45.8     27     51GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004652; F:polynucleotide adenylyltransferase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0007343; P:egg activation; IMP:FlyBase.::GO:0008298; P:intracellular mRNA localization; IMP:FlyBase.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0006378; P:mRNA polyadenylation; IMP:FlyBase.::GO:0001556; P:oocyte maturation; IMP:FlyBase.::GO:0007344; P:pronuclear fusion; IMP:FlyBase.::GO:0035046; P:pronuclear migration; IMP:FlyBase.::GO:0002805; P:regulation of antimicrobial peptide biosynthetic process; IMP:FlyBase.::GO:0035044; P:sperm aster formation; IMP:FlyBase.::GO:0007056; P:spindle assembly involved in female meiosis; IMP:FlyBase.
32O42617    558   PAP_CANAL Poly(A) polymerase PAPalpha OS=Cand...2120.002     45.1     24     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004652; F:polynucleotide adenylyltransferase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0043631; P:RNA polyadenylation; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.
33Q9UW26    555   PAPA_CANAL Poly(A) polymerase PAPa OS=Candida...1950.002     45.1     24     38GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004652; F:polynucleotide adenylyltransferase activity; IDA:CGD.::GO:0003723; F:RNA binding; IDA:CGD.
GO:0006378; P:mRNA polyadenylation; IDA:CGD.::GO:0044011; P:single-species biofilm formation on inanimate substrate; IMP:CGD.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.
34A9JTS5    843   STPAP_XENTR Speckle targeted PIP5K1A-regulate...2410.012     42.4     24     39GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0004652; F:polynucleotide adenylyltransferase activity; ISS:UniProtKB.::GO:0050265; F:RNA uridylyltransferase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006379; P:mRNA cleavage; ISS:UniProtKB.::GO:0006378; P:mRNA polyadenylation; ISS:UniProtKB.::GO:0016180; P:snRNA processing; ISS:UniProtKB.
35Q4KMD7    797   STPAP_DANRE Speckle targeted PIP5K1A-regulate...2550.035     40.8     19     39GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0004652; F:polynucleotide adenylyltransferase activity; ISS:UniProtKB.::GO:0050265; F:RNA uridylyltransferase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006379; P:mRNA cleavage; ISS:UniProtKB.::GO:0006378; P:mRNA polyadenylation; ISS:UniProtKB.::GO:0016180; P:snRNA processing; ISS:UniProtKB.
36P51006    400   PAPO3_XENLA Poly(A) polymerase type 3 OS=Xeno...2050.048     40     24     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004652; F:polynucleotide adenylyltransferase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0043631; P:RNA polyadenylation; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.
37Q9NRJ5    636   PAPOB_HUMAN Poly(A) polymerase beta OS=Homo s...1770.068     39.7     22     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004652; F:polynucleotide adenylyltransferase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0043631; P:RNA polyadenylation; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.
38Q9WVP6    641   PAPOB_MOUSE Poly(A) polymerase beta OS=Mus mu...2770.068     39.7     22     38GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005783; C:endoplasmic reticulum; IPI:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004652; F:polynucleotide adenylyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0043631; P:RNA polyadenylation; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.
39Q61183    739   PAPOA_MOUSE Poly(A) polymerase alpha OS=Mus m...2220.07     39.7     23     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0030145; F:manganese ion binding; ISS:UniProtKB.::GO:0004652; F:polynucleotide adenylyltransferase activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0043631; P:RNA polyadenylation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.
40P25500    739   PAPOA_BOVIN Poly(A) polymerase alpha OS=Bos t...2220.07     39.7     23     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0004652; F:polynucleotide adenylyltransferase activity; IDA:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0043631; P:RNA polyadenylation; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.
41P51003    745   PAPOA_HUMAN Poly(A) polymerase alpha OS=Homo ...2220.07     39.7     23     39GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0030145; F:manganese ion binding; ISS:UniProtKB.::GO:0004652; F:polynucleotide adenylyltransferase activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; NAS:UniProtKB.
GO:0006378; P:mRNA polyadenylation; NAS:UniProtKB.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; TAS:Reactome.::GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
42Q51D88    522   PAP_ENTHI Poly(A) polymerase OS=Entamoeba his...2730.22     38.1     21     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004652; F:polynucleotide adenylyltransferase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0043631; P:RNA polyadenylation; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.
43Q9BWT3    736   PAPOG_HUMAN Poly(A) polymerase gamma OS=Homo ...1700.23     38.1     25     36GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004652; F:polynucleotide adenylyltransferase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0043631; P:RNA polyadenylation; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.
44Q6PCL9    739   PAPOG_MOUSE Poly(A) polymerase gamma OS=Mus m...1700.27     37.7     25     36GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004652; F:polynucleotide adenylyltransferase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0043631; P:RNA polyadenylation; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.
45P29468    568   PAP_YEAST Poly(A) polymerase OS=Saccharomyces...800.33     37.4     34     54GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; IDA:SGD.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004652; F:polynucleotide adenylyltransferase activity; IDA:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006378; P:mRNA polyadenylation; IDA:SGD.::GO:0071050; P:snoRNA polyadenylation; IGI:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.
46P16050    662   LOX15_HUMAN Arachidonate 15-lipoxygenase OS=H...840.35     37.4     29     45GO:0005634; C:nucleus; IDA:HPA.
GO:0050473; F:arachidonate 15-lipoxygenase activity; IEA:EC.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016165; F:lipoxygenase activity; TAS:ProtInc.
GO:0006954; P:inflammatory response; TAS:ProtInc.::GO:0019370; P:leukotriene biosynthetic process; IEA:UniProtKB-KW.
47Q5RBE8    662   LOX15_PONAB Arachidonate 15-lipoxygenase OS=P...840.38     37.4     29     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050473; F:arachidonate 15-lipoxygenase activity; IEA:EC.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016165; F:lipoxygenase activity; IEA:InterPro.
GO:0019370; P:leukotriene biosynthetic process; IEA:UniProtKB-KW.
48Q1JPD6    871   STPAP_BOVIN Speckle targeted PIP5K1A-regulate...880.7     36.6     26     48GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0004652; F:polynucleotide adenylyltransferase activity; ISS:UniProtKB.::GO:0050265; F:RNA uridylyltransferase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006379; P:mRNA cleavage; ISS:UniProtKB.::GO:0006378; P:mRNA polyadenylation; ISS:UniProtKB.::GO:0016180; P:snRNA processing; ISS:UniProtKB.
49Q8TGY5    485   CCA_METKA CCA-adding enzyme OS=100938). GN=cc...580.95     35.8     36     62
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0052929; F:ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity; IEA:EC.::GO:0052928; F:CTP:3'-cytidine-tRNA cytidylyltransferase activity; IEA:EC.::GO:0052927; F:CTP:tRNA cytidylyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004810; F:tRNA adenylyltransferase activity; IEA:InterPro.::GO:0016437; F:tRNA cytidylyltransferase activity; IEA:InterPro.
GO:0042245; P:RNA repair; IEA:UniProtKB-KW.::GO:0001680; P:tRNA 3'-terminal CCA addition; IEA:EC.
50Q14289    1009   FAK2_HUMAN Protein-tyrosine kinase 2-beta OS=...918.2     33.1     27     44GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; NAS:ProtInc.
GO:0042976; P:activation of Janus kinase activity; IMP:UniProtKB.::GO:0006915; P:apoptotic process; TAS:ProtInc.::GO:0045453; P:bone resorption; ISS:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0070098; P:chemokine-mediated signaling pathway; ISS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0002315; P:marginal zone B cell differentiation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0030502; P:negative regulation of bone mineralization; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; IMP:UniProtKB.::GO:0043267; P:negative regulation of potassium ion transport; IDA:UniProtKB.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.::GO:2000538; P:positive regulation of B cell chemotaxis; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0001954; P:positive regulation of cell-matrix adhesion; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:2000249; P:regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032960; P:regulation of inositol trisphosphate biosynthetic process; ISS:UniProtKB.::GO:0010758; P:regulation of macrophage chemotaxis; ISS:UniProtKB.::GO:2000058; P:regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051279; P:regulation of release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0007172; P:signal complex assembly; TAS:ProtInc.::GO:0002040; P:sprouting angiogenesis; ISS:UniProtKB.::GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IMP:UniProtKB.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL.
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