Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL113W
Length:
655
Number of sequences:
5887
Description:
YOL113W SKM1 SGDID:S000005473, Chr XV from 104326-106293, Genome Release 64-1-1, Verified ORF, "Member of the PAK family of serine/threonine protein kinases with similarity to Ste20p and Cla4p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
751Q0VBZ0    450   CSK_BOVIN Tyrosine-protein kinase CSK OS=Bos ...2367e-20     96.7     28     46GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
752O59853    420   HOG2_ZYGRO Mitogen-activated protein kinase H...2107e-20     95.9     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
753Q9SXB8    842   Y1133_ARATH G-type lectin S-receptor-like ser...3287e-20     98.2     28     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0044459; C:plasma membrane part; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0048544; P:recognition of pollen; IEA:InterPro.
754Q6BS08    875   ATG1_DEBHA Serine/threonine-protein kinase AT...2727e-20     98.2     29     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
755Q63433    946   PKN1_RAT Serine/threonine-protein kinase N1 O...1827e-20     98.2     34     54GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0017049; F:GTP-Rho binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042826; F:histone deacetylase binding; ISS:UniProtKB.::GO:0035402; F:histone kinase activity (H3-T11 specific); ISS:UniProtKB.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0048365; F:Rac GTPase binding; ISS:UniProtKB.
GO:0010631; P:epithelial cell migration; ISS:UniProtKB.::GO:2000145; P:regulation of cell motility; ISS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
756P11837    699   NIMA_EMENI G2-specific protein kinase nimA OS...3007e-20     97.8     25     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
757Q86HN7    978   PLK_DICDI Probable serine/threonine-protein k...2897e-20     98.2     25     47GO:0005813; C:centrosome; TAS:dictyBase.::GO:0005819; C:spindle; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0007067; P:mitosis; ISS:dictyBase.
758O15021    2626   MAST4_HUMAN Microtubule-associated serine/thr...2517e-20     98.6     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
759Q17941    541   AKT1_CAEEL Serine/threonine-protein kinase ak...1738e-20     97.1     31     51GO:0005622; C:intracellular; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IDA:WormBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:WormBase.
GO:0043053; P:dauer entry; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0008286; P:insulin receptor signaling pathway; IMP:WormBase.
760Q95QC4    802   DCLK_CAEEL Serine/threonine-protein kinase zy...2318e-20     97.8     29     48GO:0005813; C:centrosome; IDA:WormBase.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:WormBase.::GO:0008017; F:microtubule binding; IDA:WormBase.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0040001; P:establishment of mitotic spindle localization; IMP:WormBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007020; P:microtubule nucleation; IMP:WormBase.::GO:0046785; P:microtubule polymerization; IMP:WormBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007026; P:negative regulation of microtubule depolymerization; IDA:WormBase.
761Q7X996    443   CIPK2_ORYSJ CBL-interacting protein kinase 2 ...2408e-20     96.3     28     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
762Q15418    735   KS6A1_HUMAN Ribosomal protein S6 kinase alpha...2519e-20     97.4     26     50GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0045597; P:positive regulation of cell differentiation; TAS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; TAS:UniProtKB.::GO:2000491; P:positive regulation of hepatic stellate cell activation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043620; P:regulation of DNA-dependent transcription in response to stress; TAS:UniProtKB.::GO:0043555; P:regulation of translation in response to stress; TAS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
763Q8ICR0    509   CDPK2_PLAF7 Calcium-dependent protein kinase ...3019e-20     96.7     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:GeneDB_Pfalciparum.
764Q8RXT4    555   NEK4_ARATH Serine/threonine-protein kinase Ne...2499e-20     97.1     25     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
765Q9LDI3    446   CIPKO_ARATH CBL-interacting serine/threonine-...2389e-20     96.3     28     50GO:0009705; C:plant-type vacuole membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009651; P:response to salt stress; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
766P18653    724   KS6A1_MOUSE Ribosomal protein S6 kinase alpha...2681e-19     97.1     26     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:2000491; P:positive regulation of hepatic stellate cell activation; ISS:UniProtKB.
767Q00078    1096   KPC1_ASPNG Protein kinase C-like OS=Aspergill...1641e-19     97.8     32     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
768Q9ZSA3    498   CDPKM_ARATH Calcium-dependent protein kinase ...2301e-19     96.7     29     53GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
769P18161    1155   SPLB_DICDI Dual specificity protein kinase sp...2911e-19     97.8     30     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
770Q12263    1142   GIN4_YEAST Serine/threonine-protein kinase GI...2931e-19     97.8     27     47GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007117; P:budding cell bud growth; IGI:SGD.::GO:0046777; P:protein autophosphorylation; IDA:SGD.::GO:0000135; P:septin checkpoint; IMP:SGD.::GO:0000921; P:septin ring assembly; IGI:SGD.
771O15865    513   CDPK2_PLAFK Calcium-dependent protein kinase ...3011e-19     96.7     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
772Q8NU97    469   PKN2_CORGL Serine/threonine-protein kinases p...1741e-19     96.3     29     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
773P36582    988   PCK1_SCHPO Protein kinase C-like 1 OS=Schizos...1621e-19     97.8     30     52GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004697; F:protein kinase C activity; TAS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0090334; P:regulation of cell wall (1->3)-beta-D-glucan biosynthetic process; IMP:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase.
774Q641K5    658   NUAK1_MOUSE NUAK family SNF1-like kinase 1 OS...2761e-19     97.1     29     46GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030155; P:regulation of cell adhesion; ISS:UniProtKB.::GO:2000772; P:regulation of cellular senescence; ISS:UniProtKB.::GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.
775Q3UTQ8    938   CDKL5_MOUSE Cyclin-dependent kinase-like 5 OS...2381e-19     97.4     27     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
776Q6ZWH5    1172   NEK10_HUMAN Serine/threonine-protein kinase N...3201e-19     97.8     26     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
777Q6X4A2    449   CIPKV_ORYSJ CBL-interacting protein kinase 31...2801e-19     95.9     26     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
778B2GUY1    924   PLK4_RAT Serine/threonine-protein kinase PLK4...2861e-19     97.4     24     44GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB.
779Q7XIW5    443   CIPKT_ORYSJ CBL-interacting protein kinase 29...2771e-19     95.9     26     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
780O62305    720   KCC2D_CAEEL Calcium/calmodulin-dependent prot...2641e-19     97.1     25     51GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009931; F:calcium-dependent protein serine/threonine kinase activity; IDA:WormBase.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:WormBase.::GO:0044325; F:ion channel binding; IPI:WormBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0040011; P:locomotion; IMP:WormBase.::GO:0007067; P:mitosis; IMP:WormBase.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:WormBase.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
781Q0CLX3    964   ATG1_ASPTN Serine/threonine-protein kinase at...2261e-19     97.4     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
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