Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL100W
Length:
1081
Number of sequences:
5887
Description:
YOL100W PKH2 SGDID:S000005460, Chr XV from 129237-132482, Genome Release 64-1-1, Verified ORF, "Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
931Q863I2    529   OXSR1_PIG Serine/threonine-protein kinase OSR...3452e-23     109     26     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.
932P0C5D6    334   SAPK3_ORYSJ Serine/threonine-protein kinase S...2692e-23     107     29     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
933A2ZAB5    334   SAPK3_ORYSI Serine/threonine-protein kinase S...2692e-23     107     29     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
934Q28824    1176   MYLK_BOVIN Myosin light chain kinase, smooth ...2662e-23     111     28     48GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
935Q96PY6    1258   NEK1_HUMAN Serine/threonine-protein kinase Ne...2642e-23     111     27     50GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0000242; C:pericentriolar material; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042384; P:cilium assembly; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
936P31374    1356   PSK1_YEAST Serine/threonine-protein kinase PS...3312e-23     111     29     50GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IMP:SGD.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0045719; P:negative regulation of glycogen biosynthetic process; IMP:SGD.::GO:0060917; P:regulation of (1->6)-beta-D-glucan biosynthetic process; IGI:SGD.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
937D4AE59    438   STK11_RAT Serine/threonine-protein kinase STK...2832e-23     107     28     50GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016020; C:membrane; ISS:UniProtKB.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0030295; F:protein kinase activator activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IMP:RGD.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; IMP:RGD.::GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0045722; P:positive regulation of gluconeogenesis; IMP:RGD.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0033762; P:response to glucagon stimulus; IEP:RGD.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.::GO:0033993; P:response to lipid; IDA:RGD.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0001944; P:vasculature development; ISS:UniProtKB.
938Q8TDX7    302   NEK7_HUMAN Serine/threonine-protein kinase Ne...2412e-23     106     28     51GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0000910; P:cytokinesis; TAS:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; TAS:UniProtKB.::GO:0051225; P:spindle assembly; TAS:UniProtKB.
939Q3UTQ8    938   CDKL5_MOUSE Cyclin-dependent kinase-like 5 OS...2313e-23     110     30     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
940P22517    447   KCC2_YEAST Calcium/calmodulin-dependent prote...2573e-23     107     29     49GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:SGD.
GO:0007165; P:signal transduction; NAS:SGD.
941Q15746    1914   MYLK_HUMAN Myosin light chain kinase, smooth ...2663e-23     111     27     48GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0001725; C:stress fiber; IDA:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IDA:UniProtKB.
GO:0060414; P:aorta smooth muscle tissue morphogenesis; IMP:BHF-UCL.::GO:0032060; P:bleb assembly; IMP:UniProtKB.::GO:0071476; P:cellular hypotonic response; IDA:UniProtKB.::GO:0051928; P:positive regulation of calcium ion transport; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.::GO:0090303; P:positive regulation of wound healing; IDA:UniProtKB.::GO:0014820; P:tonic smooth muscle contraction; ISS:UniProtKB.
942P33674    391   CSK21_RABIT Casein kinase II subunit alpha OS...2653e-23     107     30     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
943Q5ZJH6    468   ULK3_CHICK Serine/threonine-protein kinase UL...2713e-23     107     28     49GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
944Q08217    1101   PSK2_YEAST Serine/threonine-protein kinase PS...2973e-23     110     30     49GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0045719; P:negative regulation of glycogen biosynthetic process; IMP:SGD.::GO:0060917; P:regulation of (1->6)-beta-D-glucan biosynthetic process; IGI:SGD.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
945P34314    965   TLK1_CAEEL Serine/threonine-protein kinase to...3233e-23     110     28     47GO:0000790; C:nuclear chromatin; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IMP:UniProtKB.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0045860; P:positive regulation of protein kinase activity; IDA:WormBase.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0006479; P:protein methylation; IMP:WormBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
946P0C1B1    902   CBK1_EMENI Serine/threonine-protein kinase cb...2603e-23     110     26     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
947Q8SWM6    488   CDC5_ENCCU Probable cell cycle serine/threoni...2653e-23     108     28     50GO:0005634; C:nucleus; IEA:UniProtKB-KW.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
948Q4U925    348   CSK2A_THEAN Casein kinase II subunit alpha OS...2583e-23     106     31     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
949Q9BXA6    273   TSSK6_HUMAN Testis-specific serine/threonine-...2184e-23     105     33     54
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0035092; P:sperm chromatin condensation; ISS:UniProtKB.
950Q7TSC3    627   NEK5_MOUSE Serine/threonine-protein kinase Ne...2754e-23     109     27     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
951E1BK52    966   STK10_BOVIN Serine/threonine-protein kinase 1...2754e-23     110     28     47GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
952Q5QN75    355   M2K1_ORYSJ Mitogen-activated protein kinase k...3204e-23     106     23     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
953P28547    348   CSK2A_THEPA Casein kinase II subunit alpha OS...2584e-23     106     31     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
954Q6CSX2    831   ATG1_KLULA Serine/threonine-protein kinase AT...3224e-23     109     24     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
955P29294    1147   MYLK_RABIT Myosin light chain kinase, smooth ...2664e-23     110     27     47GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
956P11799    1906   MYLK_CHICK Myosin light chain kinase, smooth ...2674e-23     110     27     48GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
957O76039    1030   CDKL5_HUMAN Cyclin-dependent kinase-like 5 OS...2315e-23     110     30     48GO:0032839; C:dendrite cytoplasm; ISS:BHF-UCL.::GO:0044294; C:dendritic growth cone; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:HGNC.
GO:0005524; F:ATP binding; IDA:HGNC.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0048365; F:Rac GTPase binding; ISS:BHF-UCL.
GO:0001764; P:neuron migration; ISS:BHF-UCL.::GO:0045773; P:positive regulation of axon extension; ISS:BHF-UCL.::GO:0050775; P:positive regulation of dendrite morphogenesis; ISS:BHF-UCL.::GO:0032855; P:positive regulation of Rac GTPase activity; ISS:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:HGNC.
958Q9UEE5    414   ST17A_HUMAN Serine/threonine-protein kinase 1...2715e-23     106     25     48GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:UniProtKB.
959Q03428    431   NRKB_TRYBB Putative serine/threonine-protein ...2635e-23     107     28     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
960P25390    1331   SSK22_YEAST Serine/threonine-protein kinase S...2155e-23     110     29     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000161; P:MAPK cascade involved in osmosensory signaling pathway; IMP:SGD.
961P50527    658   STE20_SCHPO Serine/threonine-protein kinase s...2695e-23     108     27     45GO:0071521; C:Cdc42 GTPase complex; TAS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0032488; P:Cdc42 protein signal transduction; IGI:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; TAS:PomBase.::GO:0061161; P:positive regulation of establishment of bipolar cell polarity regulating cell shape; IGI:PomBase.::GO:0071775; P:regulation of cell cycle cytokinesis; IMP:PomBase.::GO:0070507; P:regulation of microtubule cytoskeleton organization; IGI:PomBase.
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