Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL100W
Length:
1081
Number of sequences:
5887
Description:
YOL100W PKH2 SGDID:S000005460, Chr XV from 129237-132482, Genome Release 64-1-1, Verified ORF, "Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
721O70150    343   KCC1B_RAT Calcium/calmodulin-dependent protei...2811e-26     117     29     49GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD.
722Q96NX5    476   KCC1G_HUMAN Calcium/calmodulin-dependent prot...4091e-26     118     25     43GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
723A5A7I7    557   CDPK4_SOLTU Calcium-dependent protein kinase ...2731e-26     119     28     47GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
724Q9HFF4    1023   PPK1_SCHPO Serine/threonine-protein kinase pp...3001e-26     121     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0007165; P:signal transduction; NAS:PomBase.
725Q38872    544   CDPK6_ARATH Calcium-dependent protein kinase ...2632e-26     119     29     47GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0009738; P:abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0010359; P:regulation of anion channel activity; IMP:TAIR.::GO:0010119; P:regulation of stomatal movement; IMP:TAIR.
726Q2QMH1    591   NEK2_ORYSJ Serine/threonine-protein kinase Ne...2632e-26     119     30     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
727P23561    717   STE11_YEAST Serine/threonine-protein kinase S...1982e-26     120     33     53GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:SGD.::GO:0032093; F:SAM domain binding; IDA:SGD.
GO:0034605; P:cellular response to heat; IMP:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0000161; P:MAPK cascade involved in osmosensory signaling pathway; IMP:SGD.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0010525; P:regulation of transposition, RNA-mediated; IMP:SGD.::GO:0001402; P:signal transduction involved in filamentous growth; IMP:SGD.
728A2ZMH2    591   NEK2_ORYSI Serine/threonine-protein kinase Ne...2632e-26     119     30     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
729O08648    1597   M3K4_MOUSE Mitogen-activated protein kinase k...2982e-26     121     32     48GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0019100; P:male germ-line sex determination; IMP:MGI.::GO:0043507; P:positive regulation of JUN kinase activity; IDA:UniProtKB.
730A7A1P0    717   STE11_YEAS7 Serine/threonine-protein kinase S...1982e-26     120     33     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
731O80902    431   CIPKM_ARATH CBL-interacting serine/threonine-...2302e-26     117     31     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
732Q16816    387   PHKG1_HUMAN Phosphorylase b kinase gamma cata...2832e-26     117     28     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005964; C:phosphorylase kinase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; IEA:EC.
GO:0006006; P:glucose metabolic process; TAS:Reactome.::GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.::GO:0005980; P:glycogen catabolic process; TAS:Reactome.
733P0A5S4    626   PKNB_MYCTU Serine/threonine-protein kinase pk...2162e-26     119     30     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030145; F:manganese ion binding; IDA:MTBBASE.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MTBBASE.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MTBBASE.
GO:0040007; P:growth; IMP:MTBBASE.::GO:0043086; P:negative regulation of catalytic activity; IDA:MTBBASE.::GO:0032091; P:negative regulation of protein binding; IDA:MTBBASE.::GO:0043085; P:positive regulation of catalytic activity; IDA:MTBBASE.::GO:0043388; P:positive regulation of DNA binding; IDA:MTBBASE.::GO:0046777; P:protein autophosphorylation; IDA:MTBBASE.::GO:0008360; P:regulation of cell shape; IMP:MTBBASE.::GO:0051338; P:regulation of transferase activity; IDA:MTBBASE.::GO:0052572; P:response to host immune response; IDA:MTBBASE.
734P0A5S5    626   PKNB_MYCBO Serine/threonine-protein kinase pk...2162e-26     119     30     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
735Q9QYZ3    484   SMK2B_MOUSE Sperm motility kinase 2B OS=Mus m...2912e-26     118     25     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
736Q8AYC9    476   CHK1_CHICK Serine/threonine-protein kinase Ch...2772e-26     118     29     49GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035402; F:histone kinase activity (H3-T11 specific); ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0048096; P:chromatin-mediated maintenance of transcription; ISS:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; ISS:UniProtKB.::GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0045839; P:negative regulation of mitosis; ISS:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:2000615; P:regulation of histone H3-K9 acetylation; ISS:UniProtKB.::GO:0046602; P:regulation of mitotic centrosome separation; ISS:UniProtKB.::GO:0010767; P:regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; ISS:UniProtKB.
737P32866    714   GPRK2_DROME G protein-coupled receptor kinase...3122e-26     120     29     50GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IMP:FlyBase.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0050830; P:defense response to Gram-positive bacterium; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW.::GO:0002805; P:regulation of antimicrobial peptide biosynthetic process; IMP:FlyBase.::GO:0008589; P:regulation of smoothened signaling pathway; IDA:FlyBase.::GO:0008592; P:regulation of Toll signaling pathway; IGI:FlyBase.::GO:0007224; P:smoothened signaling pathway; IMP:FlyBase.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
738Q54MV2    715   MRKB_DICDI Probable serine/threonine-protein ...2872e-26     120     29     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
739Q09136    385   AAPK1_PIG 5'-AMP-activated protein kinase cat...2152e-26     117     31     53GO:0031588; C:AMP-activated protein kinase complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004679; F:AMP-activated protein kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0050995; P:negative regulation of lipid catabolic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
740D0N4E2    399   PKZ1_PHYIT Serine/threonine-protein kinase PK...2872e-26     117     26     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
741Q16566    473   KCC4_HUMAN Calcium/calmodulin-dependent prote...2802e-26     118     30     50GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007616; P:long-term memory; IGI:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0045670; P:regulation of osteoclast differentiation; TAS:UniProtKB.::GO:0033081; P:regulation of T cell differentiation in thymus; TAS:UniProtKB.
742Q7XQP4    359   SAPK7_ORYSJ Serine/threonine-protein kinase S...2752e-26     117     31     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
743P07934    388   PHKG1_MOUSE Phosphorylase b kinase gamma cata...2822e-26     117     27     47GO:0005964; C:phosphorylase kinase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; IEA:EC.
GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
744Q54XJ4    1495   Y8901_DICDI Probable serine/threonine-protein...2872e-26     121     25     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
745P26818    688   ARBK2_BOVIN Beta-adrenergic receptor kinase 2...3192e-26     119     27     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047696; F:beta-adrenergic receptor kinase activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
746P43250    576   GRK6_HUMAN G protein-coupled receptor kinase ...2922e-26     119     32     48GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.
GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
747P11730    527   KCC2G_RAT Calcium/calmodulin-dependent protei...2712e-26     118     28     50GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; TAS:RGD.::GO:0001666; P:response to hypoxia; IDA:RGD.::GO:0006979; P:response to oxidative stress; IDA:RGD.
748Q54BF0    593   FHKA_DICDI Probable serine/threonine-protein ...3162e-26     119     30     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0000077; P:DNA damage checkpoint; ISS:dictyBase.
749Q00168    530   KCC2A_DROME Calcium/calmodulin-dependent prot...2632e-26     118     27     51GO:0030424; C:axon; IDA:FlyBase.::GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0030425; C:dendrite; IDA:FlyBase.::GO:0045211; C:postsynaptic membrane; IDA:FlyBase.::GO:0048786; C:presynaptic active zone; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; TAS:FlyBase.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:FlyBase.
GO:0007616; P:long-term memory; IMP:FlyBase.::GO:0008049; P:male courtship behavior; IMP:FlyBase.::GO:0007528; P:neuromuscular junction development; NAS:FlyBase.::GO:0051489; P:regulation of filopodium assembly; IMP:FlyBase.::GO:0060278; P:regulation of ovulation; IGI:FlyBase.::GO:0007268; P:synaptic transmission; IMP:FlyBase.
750Q6NLQ6    538   CDPKW_ARATH Calcium-dependent protein kinase ...2742e-26     118     26     47GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004698; F:calcium-dependent protein kinase C activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009738; P:abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
751Q9HBH9    465   MKNK2_HUMAN MAP kinase-interacting serine/thr...2913e-26     117     28     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.::GO:0071243; P:cellular response to arsenic-containing substance; IDA:UniProtKB.::GO:0030097; P:hemopoiesis; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
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