Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL100W
Length:
1081
Number of sequences:
5887
Description:
YOL100W PKH2 SGDID:S000005460, Chr XV from 129237-132482, Genome Release 64-1-1, Verified ORF, "Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
421Q60806    631   PLK3_MOUSE Serine/threonine-protein kinase PL...2621e-32     138     29     48GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071779; P:G1/S transition checkpoint; IMP:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0090166; P:Golgi disassembly; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:2000777; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; IMP:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IMP:UniProtKB.::GO:0006970; P:response to osmotic stress; ISS:UniProtKB.::GO:0009314; P:response to radiation; ISS:UniProtKB.::GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; ISS:UniProtKB.
422O08678    793   MARK1_RAT Serine/threonine-protein kinase MAR...2352e-32     139     31     51GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0015630; C:microtubule cytoskeleton; NAS:RGD.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0070300; F:phosphatidic acid binding; ISS:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.::GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0000226; P:microtubule cytoskeleton organization; IDA:RGD.::GO:0001764; P:neuron migration; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
423Q8VHJ5    795   MARK1_MOUSE Serine/threonine-protein kinase M...2352e-32     139     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0070300; F:phosphatidic acid binding; ISS:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.::GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
424Q9XIW0    429   CIPK7_ARATH CBL-interacting serine/threonine-...2712e-32     135     28     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009409; P:response to cold; IEP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
425P15735    406   PHKG2_HUMAN Phosphorylase b kinase gamma cata...3273e-32     135     28     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0005964; C:phosphorylase kinase complex; TAS:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; TAS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; TAS:UniProtKB.
GO:0006006; P:glucose metabolic process; TAS:Reactome.::GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.::GO:0005980; P:glycogen catabolic process; TAS:Reactome.::GO:0045819; P:positive regulation of glycogen catabolic process; TAS:UniProtKB.
426Q14012    370   KCC1A_HUMAN Calcium/calmodulin-dependent prot...2733e-32     134     33     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0060999; P:positive regulation of dendritic spine development; IMP:UniProtKB.::GO:0051149; P:positive regulation of muscle cell differentiation; IMP:BHF-UCL.::GO:0010976; P:positive regulation of neuron projection development; IDA:UniProtKB.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0051835; P:positive regulation of synapse structural plasticity; IMP:UniProtKB.::GO:0043393; P:regulation of protein binding; IDA:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc.
427Q75L42    454   CIPKH_ORYSJ CBL-interacting protein kinase 17...2704e-32     135     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
428Q7ZVS3    940   PLK4_DANRE Serine/threonine-protein kinase PL...2734e-32     139     30     52GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.
429Q6PAD2    944   PLK4_XENLA Serine/threonine-protein kinase PL...2704e-32     139     31     53GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.
430O62846    209   KAPCG_MACMU cAMP-dependent protein kinase cat...1824e-32     130     38     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IEA:EC.
431Q2KJ16    406   PHKG2_BOVIN Phosphorylase b kinase gamma cata...3254e-32     134     27     49GO:0005964; C:phosphorylase kinase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; IEA:EC.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
432Q3E9C0    523   CDPKY_ARATH Calcium-dependent protein kinase ...2744e-32     135     29     49GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0080092; P:regulation of pollen tube growth; IMP:TAIR.
433P34100    714   PKD1_DICDI Developmentally-regulated protein ...2825e-32     137     30     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
434B0WAU8    761   PLK4_CULQU Serine/threonine-protein kinase PL...2765e-32     138     29     50GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
435P43249    590   GRK5_BOVIN G protein-coupled receptor kinase ...2925e-32     136     31     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
436Q9DB30    406   PHKG2_MOUSE Phosphorylase b kinase gamma cata...3276e-32     134     27     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; IEA:EC.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
437Q1ZXI5    1350   Y1558_DICDI Probable serine/threonine-protein...3457e-32     139     29     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
438Q9M101    520   CDPKN_ARATH Calcium-dependent protein kinase ...2578e-32     135     31     49GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0046686; P:response to cadmium ion; IEP:TAIR.
439Q28GW8    652   MELK_XENTR Maternal embryonic leucine zipper ...2638e-32     136     29     52GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
440Q9FMP5    528   CDPKH_ARATH Calcium-dependent protein kinase ...2748e-32     135     28     47GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0080092; P:regulation of pollen tube growth; IMP:TAIR.
441Q8RWL2    534   CDPKT_ARATH Calcium-dependent protein kinase ...2888e-32     135     27     50GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
442P25389    1037   KCC4_YEAST Probable serine/threonine-protein ...2829e-32     138     33     50GO:0032174; C:cellular bud neck septin collar; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005940; C:septin ring; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0070300; F:phosphatidic acid binding; IDA:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.::GO:0001786; F:phosphatidylserine binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007117; P:budding cell bud growth; IMP:SGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0000135; P:septin checkpoint; IGI:SGD.::GO:0000921; P:septin ring assembly; IMP:SGD.
443Q9LT35    416   NEK6_ARATH Serine/threonine-protein kinase Ne...2719e-32     134     30     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
444Q10364    646   SCK2_SCHPO Serine/threonine-protein kinase sc...2931e-31     136     32     54GO:0005829; C:cytosol; IDA:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0001320; P:age-dependent response to reactive oxygen species involved in chronological cell aging; IGI:PomBase.::GO:0019933; P:cAMP-mediated signaling; IMP:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IGI:PomBase.
445Q54QI2    941   Y9877_DICDI Serine/threonine-protein kinase D...2691e-31     137     29     48GO:0016020; C:membrane; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
446Q62833    590   GRK5_RAT G protein-coupled receptor kinase 5 ...2921e-31     135     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IC:RGD.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0002029; P:desensitization of G-protein coupled receptor protein signaling pathway; IMP:RGD.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0042493; P:response to drug; IEP:RGD.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
447Q91YS8    374   KCC1A_MOUSE Calcium/calmodulin-dependent prot...2731e-31     132     32     53GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; IDA:MGI.::GO:0060999; P:positive regulation of dendritic spine development; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0046827; P:positive regulation of protein export from nucleus; IDA:MGI.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0051835; P:positive regulation of synapse structural plasticity; ISS:UniProtKB.::GO:0043393; P:regulation of protein binding; ISS:UniProtKB.::GO:0007165; P:signal transduction; IDA:MGI.
448Q54VI1    712   FHKE_DICDI Probable serine/threonine-protein ...2921e-31     136     29     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0000077; P:DNA damage checkpoint; ISS:dictyBase.
449Q63450    374   KCC1A_RAT Calcium/calmodulin-dependent protei...2731e-31     132     32     53GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0060999; P:positive regulation of dendritic spine development; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0051835; P:positive regulation of synapse structural plasticity; ISS:UniProtKB.::GO:0051147; P:regulation of muscle cell differentiation; ISS:UniProtKB.::GO:0043393; P:regulation of protein binding; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.
450P49101    513   CDPK2_MAIZE Calcium-dependent protein kinase ...2742e-31     134     27     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
451Q91821    651   MELK_XENLA Maternal embryonic leucine zipper ...2632e-31     135     29     52GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
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