| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P45181 | 926 | PQQL_HAEIN Probable zinc protease pqqL OS=Hae... | 184 | 0.00002 | 52 | 25 | 48 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 32 | P11913 | 476 | MPPB_NEUCR Mitochondrial-processing peptidase... | 206 | 0.00003 | 51.6 | 24 | 46 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 33 | O14077 | 969 | MU138_SCHPO Putative zinc protease mug138 OS=... | 221 | 0.00003 | 51.6 | 25 | 44 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0071432; P:peptide mating pheromone maturation involved in conjugation with cellular fusion; ISS:PomBase.::GO:0006508; P:proteolysis; ISS:PomBase. | 34 | O43847 | 1150 | NRDC_HUMAN Nardilysin OS=Homo sapiens (Human)... | 211 | 0.00004 | 51.6 | 26 | 40 | GO:0009986; C:cell surface; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:UniProtKB. | | | | | | | | | | GO:0048408; F:epidermal growth factor binding; TAS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0007528; P:neuromuscular junction development; TAS:ProtInc.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:0006508; P:proteolysis; NAS:UniProtKB.::GO:0052548; P:regulation of endopeptidase activity; IDA:BHF-UCL. | 35 | Q9P7X1 | 457 | MPPB_SCHPO Probable mitochondrial-processing ... | 195 | 0.00008 | 50.1 | 28 | 45 | GO:0017087; C:mitochondrial processing peptidase complex; ISS:PomBase.::GO:0005750; C:mitochondrial respiratory chain complex III; ISS:PomBase. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009060; P:aerobic respiration; ISS:PomBase.::GO:0006627; P:protein processing involved in protein targeting to mitochondrion; ISS:PomBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 36 | P14735 | 1019 | IDE_HUMAN Insulin-degrading enzyme OS=Homo sa... | 219 | 0.0001 | 50.4 | 26 | 42 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; IDA:UniProtKB.::GO:0010815; P:bradykinin catabolic process; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. | 37 | P47245 | 1161 | NRDC_RAT Nardilysin OS=Rattus norvegicus (Rat... | 214 | 0.0001 | 50.1 | 25 | 41 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 38 | Q8BHG1 | 1161 | NRDC_MOUSE Nardilysin OS=Mus musculus (Mouse)... | 214 | 0.0001 | 50.1 | 25 | 41 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 39 | Q24K02 | 1019 | IDE_BOVIN Insulin-degrading enzyme OS=Bos tau... | 219 | 0.0001 | 50.1 | 26 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0010815; P:bradykinin catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 40 | O22941 | 970 | PXM16_ARATH Zinc-metallopeptidase, peroxisoma... | 199 | 0.0002 | 48.9 | 22 | 43 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 41 | Q5R4H6 | 1152 | NRDC_PONAB Nardilysin OS=Pongo abelii (Sumatr... | 211 | 0.0002 | 48.9 | 26 | 40 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 42 | P55679 | 512 | Y4WA_RHISN Uncharacterized zinc protease y4wA... | 199 | 0.0005 | 47.8 | 23 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 43 | Q9JHR7 | 1019 | IDE_MOUSE Insulin-degrading enzyme OS=Mus mus... | 218 | 0.0008 | 47.4 | 25 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0010815; P:bradykinin catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 44 | Q3SZ71 | 490 | MPPB_BOVIN Mitochondrial-processing peptidase... | 205 | 0.001 | 46.6 | 26 | 43 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 45 | Q10040 | 856 | YQA4_CAEEL Putative zinc protease C28F5.4 OS=... | 188 | 0.001 | 47 | 27 | 41 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 46 | P35559 | 1019 | IDE_RAT Insulin-degrading enzyme OS=Rattus no... | 219 | 0.001 | 47 | 26 | 42 | GO:0009986; C:cell surface; IDA:RGD.::GO:0031597; C:cytosolic proteasome complex; IDA:RGD.::GO:0005615; C:extracellular space; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005782; C:peroxisomal matrix; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016887; F:ATPase activity; IDA:RGD.::GO:0001540; F:beta-amyloid binding; IPI:RGD.::GO:0031626; F:beta-endorphin binding; IMP:RGD.::GO:0043559; F:insulin binding; IMP:RGD.::GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0010815; P:bradykinin catabolic process; ISS:UniProtKB.::GO:0042447; P:hormone catabolic process; IDA:RGD.::GO:0045861; P:negative regulation of proteolysis; IDA:RGD.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0051289; P:protein homotetramerization; IDA:RGD.::GO:0051603; P:proteolysis involved in cellular protein catabolic process; IMP:RGD. | 47 | O75439 | 489 | MPPB_HUMAN Mitochondrial-processing peptidase... | 180 | 0.001 | 46.2 | 26 | 45 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0044267; P:cellular protein metabolic process; TAS:Reactome.::GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 48 | Q5REK3 | 489 | MPPB_PONAB Mitochondrial-processing peptidase... | 180 | 0.001 | 46.2 | 26 | 45 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 49 | Q54JQ2 | 962 | IDE_DICDI Insulin-degrading enzyme homolog OS... | 203 | 0.006 | 44.3 | 24 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 50 | Q03346 | 489 | MPPB_RAT Mitochondrial-processing peptidase s... | 180 | 0.007 | 43.9 | 26 | 45 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006627; P:protein processing involved in protein targeting to mitochondrion; TAS:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 51 | Q4W6B5 | 469 | MPPB_DICDI Mitochondrial-processing peptidase... | 204 | 0.016 | 42.7 | 24 | 47 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0017087; C:mitochondrial processing peptidase complex; ISS:dictyBase.::GO:0031982; C:vesicle; IDA:dictyBase. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; ISS:dictyBase.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0031930; P:mitochondria-nucleus signaling pathway; IMP:dictyBase.::GO:0006627; P:protein processing involved in protein targeting to mitochondrion; ISS:dictyBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 52 | P10507 | 462 | MPPB_YEAST Mitochondrial-processing peptidase... | 201 | 0.016 | 42.7 | 20 | 45 | GO:0017087; C:mitochondrial processing peptidase complex; IDA:SGD. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; TAS:Reactome.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006627; P:protein processing involved in protein targeting to mitochondrion; IDA:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 53 | Q9CXT8 | 489 | MPPB_MOUSE Mitochondrial-processing peptidase... | 180 | 0.019 | 42.4 | 25 | 44 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 54 | Q42290 | 531 | MPPB_ARATH Probable mitochondrial-processing ... | 195 | 0.032 | 41.6 | 23 | 45 | GO:0005618; C:cell wall; IDA:TAIR.::GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005758; C:mitochondrial intermembrane space; IDA:TAIR.::GO:0005759; C:mitochondrial matrix; IDA:TAIR.::GO:0005741; C:mitochondrial outer membrane; IDA:TAIR.::GO:0005750; C:mitochondrial respiratory chain complex III; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IDA:TAIR. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 55 | Q9Y8B5 | 466 | MPPB_LENED Mitochondrial-processing peptidase... | 193 | 0.044 | 41.2 | 23 | 43 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 56 | Q8X6M8 | 962 | PTRA_ECO57 Protease 3 OS=Escherichia coli O15... | 211 | 0.093 | 40.4 | 23 | 37 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 57 | P05458 | 962 | PTRA_ECOLI Protease 3 OS=Escherichia coli (st... | 211 | 0.097 | 40.4 | 23 | 37 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IDA:EcoCyc. | 58 | Q83QC3 | 962 | PTRA_SHIFL Protease 3 OS=Shigella flexneri. G... | 211 | 0.11 | 40.4 | 23 | 37 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 59 | Q8CVS2 | 962 | PTRA_ECOL6 Protease 3 OS=Escherichia coli O6:... | 211 | 0.11 | 40.4 | 23 | 37 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 60 | Q06010 | 1027 | STE23_YEAST A-factor-processing enzyme OS=Sac... | 190 | 0.13 | 40 | 24 | 39 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0000300; C:peripheral to membrane of membrane fraction; IDA:SGD. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007323; P:peptide pheromone maturation; IGI:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019236; P:response to pheromone; IEA:UniProtKB-KW. | 61 | Q1RJ61 | 412 | Y522_RICBR Uncharacterized zinc protease RBE_... | 193 | 0.16 | 39.3 | 23 | 42 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
