Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL094C
Length:
323
Number of sequences:
5887
Description:
YOL094C RFC4 SGDID:S000005454, Chr XV from 142555-141584, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151P35251    1148   RFC1_HUMAN Replication factor C subunit 1 OS=...2380.0000002     55.8     25     39GO:0005663; C:DNA replication factor C complex; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; TAS:ProtInc.::GO:0003689; F:DNA clamp loader activity; IEA:InterPro.::GO:0008047; F:enzyme activator activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.::GO:0006297; P:nucleotide-excision repair, DNA gap filling; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.::GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.::GO:0007004; P:telomere maintenance via telomerase; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
152Q89A95    370   DPO3X_BUCBP DNA polymerase III subunit gamma ...2110.000001     53.1     24     43GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
153P0C1D3    993   CTF18_EMENI Chromosome transmission fidelity ...1180.000001     53.5     33     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
154P0AAZ4    447   RARA_ECOLI Replication-associated recombinati...2110.000003     52     25     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
155P0AAZ5    447   RARA_ECOL6 Replication-associated recombinati...2110.000003     52     25     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
156P0AAZ6    447   RARA_ECO57 Replication-associated recombinati...2110.000003     52     25     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
157Q9HIP7    418   RFCL_THEAC Replication factor C large subunit...1200.000004     51.6     31     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
158Q50739    452   Y2559_MYCTU Uncharacterized AAA domain-contai...2100.000006     51.2     26     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
159Q8CG07    660   WRIP1_RAT ATPase WRNIP1 OS=Rattus norvegicus ...2310.000006     51.2     23     43GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0000731; P:DNA synthesis involved in DNA repair; ISS:UniProtKB.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; ISS:UniProtKB.
160Q04UI9    341   RUVB_LEPBJ Holliday junction ATP-dependent DN...2000.000006     50.8     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009378; F:four-way junction helicase activity; IEA:InterPro.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
161Q04YY5    341   RUVB_LEPBL Holliday junction ATP-dependent DN...2000.000007     50.8     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009378; F:four-way junction helicase activity; IEA:InterPro.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
162P63975    578   DPO3X_MYCTU DNA polymerase III subunit gamma/...2280.000007     51.2     23     39GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0040007; P:growth; IMP:MTBBASE.
163P63976    578   DPO3X_MYCBO DNA polymerase III subunit gamma/...2280.000007     51.2     23     39GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
164Q91XU0    660   WRIP1_MOUSE ATPase WRNIP1 OS=Mus musculus (Mo...2310.000007     51.2     23     43GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0000731; P:DNA synthesis involved in DNA repair; ISS:UniProtKB.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; ISS:UniProtKB.
165Q75JU2    876   WRIP1_DICDI ATPase WRNIP1 OS=Dictyostelium di...2210.000009     50.8     25     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009378; F:four-way junction helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
166Q8F7Y2    341   RUVB_LEPIN Holliday junction ATP-dependent DN...2000.00001     49.7     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009378; F:four-way junction helicase activity; IEA:InterPro.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
167P61534    341   RUVB_LEPIC Holliday junction ATP-dependent DN...2000.00001     49.7     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009378; F:four-way junction helicase activity; IEA:InterPro.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
168Q97BC2    420   RFCL_THEVO Replication factor C large subunit...2770.00002     49.3     22     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
169Q96S55    665   WRIP1_HUMAN ATPase WRNIP1 OS=Homo sapiens (Hu...2310.00005     48.5     23     41GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IMP:UniProtKB.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0000731; P:DNA synthesis involved in DNA repair; IDA:UniProtKB.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IDA:UniProtKB.
170B3QM27    342   RUVB_CHLP8 Holliday junction ATP-dependent DN...630.00007     47.8     40     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009378; F:four-way junction helicase activity; IEA:InterPro.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
171P39918    440   RARA_COXBU Replication-associated recombinati...2120.00008     47.8     25     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
172Q8KC00    344   RUVB_CHLTE Holliday junction ATP-dependent DN...630.0001     47     40     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009378; F:four-way junction helicase activity; IEA:InterPro.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
173P42425    552   LON2_BACSU Lon protease 2 OS=Bacillus subtili...630.0001     47     37     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
174P61529    329   RUVB_BDEBA Holliday junction ATP-dependent DN...2440.0002     46.2     22     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009378; F:four-way junction helicase activity; IEA:InterPro.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
175Q8WVB6    975   CTF18_HUMAN Chromosome transmission fidelity ...830.0002     47     36     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
176P40151    587   WRIP1_YEAST DNA-dependent ATPase MGS1 OS=Sacc...2310.0007     45.1     27     41GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000739; F:DNA strand annealing activity; IDA:SGD.::GO:0008047; F:enzyme activator activity; IDA:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0043142; F:single-stranded DNA-dependent ATPase activity; IDA:SGD.::GO:0043130; F:ubiquitin binding; ISS:SGD.
GO:0006952; P:defense response; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0033567; P:DNA replication, Okazaki fragment processing; IDA:SGD.::GO:0006282; P:regulation of DNA repair; IGI:SGD.
177Q6NU40    1000   CTF18_XENLA Chromosome transmission fidelity ...1890.0007     45.1     24     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
178O13984    504   WRIP1_SCHPO ATPase WRNIP1 homolog C26H5.02c O...2150.0009     44.3     25     41GO:0005634; C:nucleus; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0043142; F:single-stranded DNA-dependent ATPase activity; ISS:PomBase.
GO:0033567; P:DNA replication, Okazaki fragment processing; ISS:PomBase.::GO:0000731; P:DNA synthesis involved in DNA repair; ISS:PomBase.
179Q5UQK9    533   RFCL_MIMIV Putative replication factor C larg...530.001     43.9     40     62GO:0005663; C:DNA replication factor C complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003689; F:DNA clamp loader activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
180B3ER84    342   RUVB_AMOA5 Holliday junction ATP-dependent DN...560.001     43.5     39     61
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009378; F:four-way junction helicase activity; IEA:InterPro.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
181P50531    606   RAD17_SCHPO Checkpoint protein rad17 OS=Schiz...2570.001     43.9     23     42GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0031389; C:Rad17 RFC-like complex; TAS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031573; P:intra-S DNA damage checkpoint; IMP:PomBase.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; IMP:PomBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IMP:PomBase.
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