Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL090W
Length:
964
Number of sequences:
5887
Description:
YOL090W MSH2 SGDID:S000005450, Chr XV from 147382-150276, Genome Release 64-1-1, Verified ORF, "Protein that forms heterodimers with Msh3p and Msh6p that bind to DNA mismatches to initiate the mismatch repair process; contains a Walker ATP-binding motif required for repair activity; Msh2p-Msh6p binds to and hydrolyzes ATP"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P25847    964   MSH2_YEAST DNA mismatch repair protein MSH2 O...9640     1980     100     100GO:0032301; C:MutSalpha complex; IPI:SGD.::GO:0032302; C:MutSbeta complex; IPI:SGD.::GO:0000228; C:nuclear chromosome; IDA:SGD.
GO:0005524; F:ATP binding; IDA:SGD.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IDA:SGD.::GO:0000400; F:four-way junction DNA binding; IDA:SGD.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030466; P:chromatin silencing at silent mating-type cassette; IGI:SGD.::GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0006311; P:meiotic gene conversion; IMP:SGD.::GO:0000710; P:meiotic mismatch repair; IMP:SGD.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0006301; P:postreplication repair; IBA:RefGenome.::GO:0000735; P:removal of nonhomologous ends; IMP:SGD.
2O13396    937   MSH2_NEUCR DNA mismatch repair protein msh-2 ...9600     870     47     66GO:0032301; C:MutSalpha complex; IBA:RefGenome.::GO:0032302; C:MutSbeta complex; IBA:RefGenome.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IBA:RefGenome.::GO:0000404; F:loop DNA binding; IBA:RefGenome.::GO:0032138; F:single base insertion or deletion binding; IBA:RefGenome.::GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0006311; P:meiotic gene conversion; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0006301; P:postreplication repair; IBA:RefGenome.::GO:0000735; P:removal of nonhomologous ends; IBA:RefGenome.
3O74773    982   MSH2_SCHPO DNA mismatch repair protein msh2 O...10250     728     42     60GO:0005829; C:cytosol; IDA:PomBase.::GO:0032301; C:MutSalpha complex; ISS:RefGenome.::GO:0032302; C:MutSbeta complex; ISS:RefGenome.::GO:0000228; C:nuclear chromosome; ISS:PomBase.
GO:0005524; F:ATP binding; ISS:PomBase.::GO:0003684; F:damaged DNA binding; ISS:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; ISS:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; ISS:PomBase.::GO:0000400; F:four-way junction DNA binding; ISS:PomBase.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.::GO:0000403; F:Y-form DNA binding; ISS:PomBase.
GO:0043570; P:maintenance of DNA repeat elements; IMP:PomBase.::GO:0006311; P:meiotic gene conversion; ISS:RefGenome.::GO:0000710; P:meiotic mismatch repair; ISS:RefGenome.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; ISS:RefGenome.::GO:0006301; P:postreplication repair; ISS:RefGenome.::GO:0000735; P:removal of nonhomologous ends; ISS:RefGenome.
4P43246    934   MSH2_HUMAN DNA mismatch repair protein Msh2 O...9280     697     41     62GO:0032301; C:MutSalpha complex; IDA:HGNC.::GO:0032302; C:MutSbeta complex; IDA:HGNC.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IMP:MGI.::GO:0000404; F:loop DNA binding; IBA:RefGenome.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:HGNC.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
GO:0030183; P:B cell differentiation; ISS:BHF-UCL.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IBA:RefGenome.::GO:0006302; P:double-strand break repair; IBA:RefGenome.::GO:0031573; P:intra-S DNA damage checkpoint; IBA:RefGenome.::GO:0045190; P:isotype switching; ISS:BHF-UCL.::GO:0043570; P:maintenance of DNA repeat elements; IMP:HGNC.::GO:0008584; P:male gonad development; ISS:BHF-UCL.::GO:0006311; P:meiotic gene conversion; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:BHF-UCL.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0051096; P:positive regulation of helicase activity; IDA:BHF-UCL.::GO:0006301; P:postreplication repair; IDA:UniProtKB.::GO:0010224; P:response to UV-B; ISS:BHF-UCL.::GO:0010165; P:response to X-ray; ISS:BHF-UCL.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.
5Q5XXB5    933   MSH2_CHLAE DNA mismatch repair protein Msh2 O...9270     697     41     62GO:0032301; C:MutSalpha complex; IEA:InterPro.::GO:0032302; C:MutSbeta complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006298; P:mismatch repair; IEA:InterPro.
6Q3MHE4    934   MSH2_BOVIN DNA mismatch repair protein Msh2 O...9510     693     40     61GO:0032301; C:MutSalpha complex; IBA:RefGenome.::GO:0032302; C:MutSbeta complex; IBA:RefGenome.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IBA:RefGenome.::GO:0000404; F:loop DNA binding; IBA:RefGenome.::GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IBA:RefGenome.::GO:0006302; P:double-strand break repair; IBA:RefGenome.::GO:0031573; P:intra-S DNA damage checkpoint; IBA:RefGenome.::GO:0045190; P:isotype switching; IBA:RefGenome.::GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0006311; P:meiotic gene conversion; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0006301; P:postreplication repair; IBA:RefGenome.::GO:0010224; P:response to UV-B; IBA:RefGenome.::GO:0010165; P:response to X-ray; IBA:RefGenome.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.
7P43247    935   MSH2_MOUSE DNA mismatch repair protein Msh2 O...9490     692     40     61GO:0032301; C:MutSalpha complex; IDA:MGI.::GO:0032302; C:MutSbeta complex; IBA:RefGenome.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019237; F:centromeric DNA binding; IDA:MGI.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0000404; F:loop DNA binding; IBA:RefGenome.::GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
GO:0006915; P:apoptotic process; IMP:MGI.::GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0007050; P:cell cycle arrest; IMP:MGI.::GO:0008340; P:determination of adult lifespan; IMP:MGI.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IBA:RefGenome.::GO:0006302; P:double-strand break repair; IMP:MGI.::GO:0007281; P:germ cell development; IMP:MGI.::GO:0001701; P:in utero embryonic development; IGI:MGI.::GO:0031573; P:intra-S DNA damage checkpoint; IGI:MGI.::GO:0045190; P:isotype switching; IMP:MGI.::GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0008584; P:male gonad development; IMP:MGI.::GO:0006311; P:meiotic gene conversion; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0006119; P:oxidative phosphorylation; IMP:MGI.::GO:0006301; P:postreplication repair; ISS:UniProtKB.::GO:0010224; P:response to UV-B; IMP:MGI.::GO:0010165; P:response to X-ray; IMP:MGI.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IMP:MGI.
8P54275    933   MSH2_RAT DNA mismatch repair protein Msh2 OS=...9490     682     40     61GO:0032301; C:MutSalpha complex; IBA:RefGenome.::GO:0032302; C:MutSbeta complex; IBA:RefGenome.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IBA:RefGenome.::GO:0000404; F:loop DNA binding; IBA:RefGenome.::GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IBA:RefGenome.::GO:0006302; P:double-strand break repair; IBA:RefGenome.::GO:0031573; P:intra-S DNA damage checkpoint; IBA:RefGenome.::GO:0045190; P:isotype switching; IBA:RefGenome.::GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0006311; P:meiotic gene conversion; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0006301; P:postreplication repair; ISS:UniProtKB.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0010224; P:response to UV-B; IBA:RefGenome.::GO:0010165; P:response to X-ray; IBA:RefGenome.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IEP:RGD.
9Q553L4    937   MSH2_DICDI DNA mismatch repair protein Msh2 O...8860     612     41     60GO:0032301; C:MutSalpha complex; ISS:dictyBase.::GO:0032302; C:MutSbeta complex; ISS:dictyBase.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IBA:RefGenome.::GO:0000404; F:loop DNA binding; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; ISS:dictyBase.::GO:0032138; F:single base insertion or deletion binding; IBA:RefGenome.::GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0006311; P:meiotic gene conversion; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0006301; P:postreplication repair; ISS:dictyBase.
10Q9XGC9    942   MSH2_MAIZE DNA mismatch repair protein MSH2 O...9770     607     38     57GO:0032301; C:MutSalpha complex; IEA:InterPro.::GO:0032302; C:MutSbeta complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
11O24617    937   MSH2_ARATH DNA mismatch repair protein Msh2 O...9350     579     38     56GO:0032301; C:MutSalpha complex; IEA:InterPro.::GO:0032302; C:MutSbeta complex; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IDA:TAIR.::GO:0030983; F:mismatched DNA binding; IDA:TAIR.::GO:0005515; F:protein binding; IPI:TAIR.
GO:0006298; P:mismatch repair; IMP:TAIR.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IMP:TAIR.::GO:0006290; P:pyrimidine dimer repair; IMP:TAIR.
12P43248    917   MSH2_DROME DNA mismatch repair protein spellc...9191e-176     544     36     57GO:0032301; C:MutSalpha complex; IBA:RefGenome.::GO:0032302; C:MutSbeta complex; IBA:RefGenome.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IBA:RefGenome.::GO:0000404; F:loop DNA binding; IBA:RefGenome.::GO:0032138; F:single base insertion or deletion binding; IBA:RefGenome.::GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IBA:RefGenome.::GO:0006302; P:double-strand break repair; IBA:RefGenome.::GO:0031573; P:intra-S DNA damage checkpoint; IBA:RefGenome.::GO:0043570; P:maintenance of DNA repeat elements; IMP:FlyBase.::GO:0006311; P:meiotic gene conversion; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0006301; P:postreplication repair; ISS:UniProtKB.::GO:0010224; P:response to UV-B; IBA:RefGenome.::GO:0010165; P:response to X-ray; IBA:RefGenome.
13B9MJU0    863   MUTS_ANATD DNA mismatch repair protein MutS O...9051e-87     305     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
14A4XL47    863   MUTS_CALS8 DNA mismatch repair protein MutS O...9012e-83     293     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
15Q87LQ9    853   MUTS_VIBPA DNA mismatch repair protein MutS O...5583e-82     290     33     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
16A7MTT8    853   MUTS_VIBHB DNA mismatch repair protein MutS O...5762e-81     287     32     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
17Q8RA71    869   MUTS_THETN DNA mismatch repair protein MutS O...6945e-81     286     32     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
18Q12VC9    887   MUTS_METBU DNA mismatch repair protein MutS O...8874e-80     284     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
19C4L191    842   MUTS_EXISA DNA mismatch repair protein MutS O...6785e-79     280     32     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
20B8I2Q5    873   MUTS_CLOCE DNA mismatch repair protein MutS O...8759e-79     280     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
21B0S1C1    856   MUTS_FINM2 DNA mismatch repair protein MutS O...8881e-78     280     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
22B7VK59    853   MUTS_VIBSL DNA mismatch repair protein MutS O...5731e-78     279     31     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
23Q5FLX5    856   MUTS_LACAC DNA mismatch repair protein MutS O...5632e-78     279     33     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
24A8YTH9    858   MUTS_LACH4 DNA mismatch repair protein MutS O...5632e-78     279     34     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
25P61668    857   MUTS_LACJO DNA mismatch repair protein MutS O...5503e-78     278     34     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
26Q045Q5    857   MUTS_LACGA DNA mismatch repair protein MutS O...5513e-78     278     34     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
27C5BGI4    852   MUTS_EDWI9 DNA mismatch repair protein MutS O...5831e-77     276     33     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
28Q8CXG6    867   MUTS_OCEIH DNA mismatch repair protein MutS O...8765e-77     275     28     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
29A1T004    856   MUTS_PSYIN DNA mismatch repair protein MutS O...5515e-77     275     34     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
30A3CR17    849   MUTS_STRSV DNA mismatch repair protein MutS O...8735e-77     275     28     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
31A7GR99    895   MUTS_BACCN DNA mismatch repair protein MutS O...5638e-77     275     34     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
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