Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL088C
Length:
277
Number of sequences:
5887
Description:
YOL088C MPD2 SGDID:S000005448, Chr XV from 154745-153912, Genome Release 64-1-1, reverse complement, Verified ORF, "Member of the protein disulfide isomerase (PDI) family, exhibits chaperone activity; overexpression suppresses the lethality of a pdi1 deletion but does not complement all Pdi1p functions; undergoes oxidation by Ero1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q6GNG3    452   TMX3_XENLA Protein disulfide-isomerase TMX3 O...1210.0004     45.1     26     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
32Q75M08    366   PDI21_ORYSJ Protein disulfide isomerase-like ...260.002     42.4     50     77GO:0005783; C:endoplasmic reticulum; IEA:InterPro.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
33P17967    522   PDI_YEAST Protein disulfide-isomerase OS=Sacc...680.051     38.5     28     50GO:0005788; C:endoplasmic reticulum lumen; IDA:SGD.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003756; F:protein disulfide isomerase activity; IDA:SGD.::GO:0015035; F:protein disulfide oxidoreductase activity; IDA:SGD.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; IMP:SGD.
34Q17770    493   PDI2_CAEEL Protein disulfide-isomerase 2 OS=C...480.0005     44.7     35     60GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IDA:WormBase.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IDA:WormBase.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IEP:WormBase.::GO:0001703; P:gastrulation with mouth forming first; IMP:WormBase.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018401; P:peptidyl-proline hydroxylation to 4-hydroxy-L-proline; IDA:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.
35Q49WR2    104   THIO_STAS1 Thioredoxin OS=DSM 20229). GN=trxA...520.0005     42.4     37     54
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
36P08003    638   PDIA4_MOUSE Protein disulfide-isomerase A4 OS...780.008     41.2     28     50GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
37Q29RV1    643   PDIA4_BOVIN Protein disulfide-isomerase A4 OS...320.008     41.2     47     59GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
38Q9XI01    501   PDI11_ARATH Protein disulfide isomerase-like ...710.017     40     30     48GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0000327; C:lytic vacuole within protein storage vacuole; IDA:TAIR.::GO:0016020; C:membrane; IDA:TAIR.::GO:0009505; C:plant-type cell wall; IDA:TAIR.::GO:0009579; C:thylakoid; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0009790; P:embryo development; IMP:TAIR.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0043067; P:regulation of programmed cell death; IMP:TAIR.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.::GO:0010043; P:response to zinc ion; IEP:TAIR.::GO:0048316; P:seed development; IMP:TAIR.
39P54399    496   PDI_DROME Protein disulfide-isomerase OS=Dros...340.001     43.9     47     71GO:0060187; C:cell pole; IDA:FlyBase.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:FlyBase.::GO:0045169; C:fusome; IDA:FlyBase.::GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0043025; C:neuronal cell body; IDA:FlyBase.::GO:0005635; C:nuclear envelope; IDA:FlyBase.::GO:0048471; C:perinuclear region of cytoplasm; IDA:FlyBase.::GO:0005791; C:rough endoplasmic reticulum; IDA:FlyBase.::GO:0070732; C:spindle envelope; IDA:FlyBase.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
40P22803    104   TRX2_YEAST Thioredoxin-2 OS=Saccharomyces cer...510.001     41.6     31     53GO:0005829; C:cytosol; IDA:SGD.::GO:0000324; C:fungal-type vacuole; IPI:SGD.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; TAS:SGD.::GO:0009263; P:deoxyribonucleotide biosynthetic process; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006888; P:ER to Golgi vesicle-mediated transport; IDA:SGD.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0080058; P:protein deglutathionylation; IDA:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006275; P:regulation of DNA replication; IGI:SGD.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IDA:SGD.::GO:0000103; P:sulfate assimilation; IGI:SGD.::GO:0042144; P:vacuole fusion, non-autophagic; IDA:SGD.::GO:0000011; P:vacuole inheritance; IMP:SGD.
41Q53LQ0    512   PDI11_ORYSJ Protein disulfide isomerase-like ...850.012     40.4     29     46GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0034975; P:protein folding in endoplasmic reticulum; IMP:UniProtKB.
42Q43116    498   PDI_RICCO Protein disulfide-isomerase OS=Rici...710.011     40.8     30     48GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
43Q10N04    147   PDI51_ORYSJ Protein disulfide isomerase-like ...1610.001     42     22     40
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
44P07237    508   PDIA1_HUMAN Protein disulfide-isomerase OS=Ho...210.12     37.4     52     71GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB.::GO:0005576; C:extracellular region; NAS:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0004656; F:procollagen-proline 4-dioxygenase activity; IDA:MGI.::GO:0003756; F:protein disulfide isomerase activity; TAS:ProtInc.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006629; P:lipid metabolic process; TAS:Reactome.::GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.::GO:0018401; P:peptidyl-proline hydroxylation to 4-hydroxy-L-proline; IDA:MGI.
45P09103    509   PDIA1_MOUSE Protein disulfide-isomerase OS=Mu...210.1     37.7     52     71GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
46Q5R5B6    508   PDIA1_PONAB Protein disulfide-isomerase OS=Po...210.13     37.4     52     71GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
47P04785    509   PDIA1_RAT Protein disulfide-isomerase OS=Ratt...220.091     37.7     50     73GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IMP:RGD.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0046982; F:protein heterodimerization activity; IPI:RGD.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
48Q2HWU2    510   PDIA1_MACFU Protein disulfide-isomerase OS=Ma...210.13     37.4     52     71GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
49P09102    515   PDIA1_CHICK Protein disulfide-isomerase OS=Ga...210.38     35.8     48     71GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
50P21195    509   PDIA1_RABIT Protein disulfide-isomerase OS=Or...340.33     35.8     38     68GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
51Q8R4U2    509   PDIA1_CRIGR Protein disulfide-isomerase OS=Cr...220.11     37.4     50     73GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
52P05307    510   PDIA1_BOVIN Protein disulfide-isomerase OS=Bo...820.055     38.5     29     44GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; ISS:AgBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0004656; F:procollagen-proline 4-dioxygenase activity; ISS:AgBase.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0018401; P:peptidyl-proline hydroxylation to 4-hydroxy-L-proline; ISS:AgBase.
53Q91W90    417   TXND5_MOUSE Thioredoxin domain-containing pro...680.25     36.2     25     51GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016853; F:isomerase activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
54P32474    517   EUG1_YEAST Protein disulfide-isomerase EUG1 O...800.002     43.1     33     49GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0003756; F:protein disulfide isomerase activity; IDA:SGD.::GO:0015035; F:protein disulfide oxidoreductase activity; IDA:SGD.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006457; P:protein folding; IGI:SGD.
55P80284    513   PDI_HORVU Protein disulfide-isomerase OS=Hord...1000.006     41.6     29     48GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
56P52589    515   PDI_WHEAT Protein disulfide-isomerase OS=Trit...990.008     41.2     28     46GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
57Q9XF61    507   PDI_DATGL Protein disulfide-isomerase OS=Dati...710.012     40.4     28     51GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
58Q8BXZ1    456   TMX3_MOUSE Protein disulfide-isomerase TMX3 O...860.002     42.7     29     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
59P12244    508   GSBP_CHICK Dolichyl-diphosphooligosaccharide-...260.84     34.7     46     62GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0004579; F:dolichyl-diphosphooligosaccharide-protein glycotransferase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016853; F:isomerase activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
60Q0E0I1    425   PDI53_ORYSJ Protein disulfide isomerase-like ...770.003     42.4     32     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
61Q8KE49    109   THIO2_CHLTE Thioredoxin-2 OS=Chlorobium tepid...1030.003     40     26     43
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
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