UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YOL088C

Length:

277

Number of sequences:

5887

Description:

YOL088C MPD2 SGDID:S000005448, Chr XV from 154745-153912, Genome Release 64-1-1, reverse complement, Verified ORF, "Member of the protein disulfide isomerase (PDI) family, exhibits chaperone activity; overexpression suppresses the lethality of a pdi1 deletion but does not complement all Pdi1p functions; undergoes oxidation by Ero1p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
151	O64394	127	TRXH_WHEAT Thioredoxin H-type OS=Triticum aes...	50	0.29	34.7	28	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
152	Q69ST6	545	PID13_ORYSJ Protein disulfide isomerase-like ...	22	0.5	35.4	45	68	GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
153	P37395	107	THIO_CYACA Thioredoxin OS=Cyanidium caldarium...	46	0.32	33.9	26	54	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
154	P66928	106	THIO_HELPY Thioredoxin OS=pylori). GN=trxA Or...	76	0.32	33.9	30	43
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
155	P66929	106	THIO_HELPJ Thioredoxin OS=Helicobacter pylori...	76	0.32	33.9	30	43
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
156	Q8VX13	579	PDI13_ARATH Protein disulfide isomerase-like ...	24	0.83	34.7	38	67	GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
									GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:TAIR.
157	Q39362	119	TRXH2_BRANA Thioredoxin H-type 2 OS=Brassica ...	41	0.4	33.9	27	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
158	O14463	103	TRX1_SCHPO Thioredoxin-1 OS=Schizosaccharomyc...	31	0.4	33.9	29	58	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0016209; F:antioxidant activity; IDA:PomBase.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0015035; F:protein disulfide oxidoreductase activity; IDA:PomBase.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0034614; P:cellular response to reactive oxygen species; IDA:PomBase.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; IDA:PomBase.::GO:0090329; P:regulation of DNA-dependent DNA replication; ISS:PomBase.::GO:0006810; P:transport; IEA:UniProtKB-KW.
159	Q18484	265	TMX2_CAEEL Thioredoxin-related transmembrane ...	73	0.4	35.4	29	52	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
160	O48737	179	TRXM1_ARATH Thioredoxin M1, chloroplastic OS=...	47	0.42	35	30	49	GO:0048046; C:apoplast; IDA:TAIR.::GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0010319; C:stromule; IDA:TAIR.::GO:0009579; C:thylakoid; IDA:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0008047; F:enzyme activator activity; IDA:UniProtKB.::GO:0004857; F:enzyme inhibitor activity; IDA:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006109; P:regulation of carbohydrate metabolic process; IDA:UniProtKB.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0006979; P:response to oxidative stress; IGI:TAIR.::GO:0006810; P:transport; IEA:UniProtKB-KW.
161	P52232	105	THIO1_SYNY3 Thioredoxin-like protein slr0233 ...	40	0.43	33.5	23	55
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
162	P21609	107	THIO_CLOLI Thioredoxin OS=Clostridium litoral...	72	0.44	33.5	29	46
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
163	P00275	105	THIO1_CORNE Thioredoxin C-1 OS=Corynebacteriu...	42	0.46	33.5	29	52
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
164	Q50KB1	223	SEP2_EMIHU Protein disulfide-isomerase-like p...	74	0.46	35	24	43	GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
									GO:0003756; F:protein disulfide isomerase activity; NAS:UniProtKB.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
165	Q8BND5	748	QSOX1_MOUSE Sulfhydryl oxidase 1 OS=Mus muscu...	80	0.49	35.4	30	49	GO:0005615; C:extracellular space; ISS:UniProtKB.::GO:0030173; C:integral to Golgi membrane; ISS:UniProtKB.
									GO:0016971; F:flavin-linked sulfhydryl oxidase activity; ISS:UniProtKB.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; ISS:UniProtKB.
166	P52231	107	THIO_SYNY3 Thioredoxin OS=Synechocystis sp. (...	41	0.5	33.5	29	54
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
167	Q5I0H9	517	PDIA5_RAT Protein disulfide-isomerase A5 OS=R...	36	2.6	33.1	31	53	GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006950; P:response to stress; ISS:UniProtKB.
168	Q09433	115	THIO1_CAEEL Thioredoxin-1 OS=Caenorhabditis e...	23	0.55	33.5	43	74	GO:0030424; C:axon; IDA:WormBase.::GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0030425; C:dendrite; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase.::GO:0031513; C:nonmotile primary cilium; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IDA:WormBase.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; IDA:WormBase.::GO:0006810; P:transport; IEA:UniProtKB-KW.
169	Q8IFW4	157	THIOT_DROME Thioredoxin-T OS=Drosophila melan...	33	0.57	34.3	36	55	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000806; C:Y chromosome; IDA:UniProtKB.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; IDA:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0006810; P:transport; IEA:UniProtKB-KW.
170	Q7M1B9	110	THIO_CHLAA Thioredoxin OS=Chloroflexus aurant...	45	0.57	33.5	27	53
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
171	Q8KEA4	101	THIO1_CHLTE Thioredoxin-1 OS=Chlorobium tepid...	51	0.57	33.1	29	45
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
172	O30974	112	THIO_MYCSM Thioredoxin OS=Mycobacterium smegm...	23	0.57	33.5	39	70
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
173	Q14554	519	PDIA5_HUMAN Protein disulfide-isomerase A5 OS...	42	2.6	33.1	29	52	GO:0005788; C:endoplasmic reticulum lumen; TAS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; TAS:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; TAS:UniProtKB.
174	Q6NPF9	172	TRXY1_ARATH Thioredoxin Y1, chloroplastic OS=...	41	0.6	34.3	24	56	GO:0009570; C:chloroplast stroma; IDA:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0008047; F:enzyme activator activity; IDA:UniProtKB.::GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IDA:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
175	Q4UNK3	105	THIO_RICFE Thioredoxin OS=Rickettsia felis (s...	46	0.6	33.1	28	52
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
176	O22022	102	THIO_CYAME Thioredoxin OS=Cyanidioschyzon mer...	45	0.6	33.1	22	53	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
177	Q92JR5	105	THIO_RICCN Thioredoxin OS=Rickettsia conorii ...	47	0.61	33.1	28	51
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
178	Q67UF5	441	PDI23_ORYSJ Protein disulfide isomerase-like ...	35	3.9	32.7	31	63	GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
179	Q9MAU6	447	PDI22_ARATH Protein disulfide-isomerase like ...	45	0.96	34.7	31	51	GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0009505; C:plant-type cell wall; IDA:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:TAIR.
180	Q11067	440	PDIA6_CAEEL Probable protein disulfide-isomer...	48	0.66	35	33	60	GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.
181	P73920	180	TXLA_SYNY3 Thiol:disulfide interchange protei...	36	0.66	34.3	33	53	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.

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