Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL068C
Length:
503
Number of sequences:
5887
Description:
YOL068C HST1 SGDID:S000005429, Chr XV from 201879-200368, Genome Release 64-1-1, reverse complement, Verified ORF, "NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p complex required for ORC-dependent silencing and mitotic repression; non-essential subunit of the Set3C deacetylase complex; involved in telomere maintenance"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q68F47    309   SIR5B_XENLA NAD-dependent protein deacylase s...2980.000000000000006     79     27     43GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
92Q8ZT00    249   NPD2_PYRAE NAD-dependent protein deacylase 2 ...2310.000000000000008     77.8     27     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
93P66816    243   NPD_STAAN NAD-dependent protein deacetylase O...2780.000000000000008     77.8     27     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
94P66815    243   NPD_STAAM NAD-dependent protein deacetylase O...2780.000000000000008     77.8     27     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
95Q8CJM9    241   NPD2_STRCO NAD-dependent protein deacetylase ...2390.00000000000001     77.4     23     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
96Q8NVC8    243   NPD_STAAW NAD-dependent protein deacetylase O...2760.00000000000001     77     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
97Q6G7B7    243   NPD_STAAS NAD-dependent protein deacetylase O...2760.00000000000001     77     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
98Q8R216    333   SIR4_MOUSE NAD-dependent protein deacetylase ...2240.00000000000002     78.2     29     47GO:0005759; C:mitochondrial matrix; ISS:UniProtKB.
GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0046676; P:negative regulation of insulin secretion; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro.
99C6A243    255   NPD_THESM NAD-dependent protein deacylase OS=...2430.00000000000002     76.6     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
100C1DBX3    248   NPD_LARHH NAD-dependent protein deacetylase O...2700.00000000000002     76.6     27     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
101O28597    245   NPD1_ARCFU NAD-dependent protein deacylase 1 ...2320.00000000000004     75.9     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
102Q1JQC6    315   SIR4_BOVIN NAD-dependent protein deacetylase ...2240.00000000000006     76.3     29     46GO:0005759; C:mitochondrial matrix; IDA:UniProtKB.
GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0046676; P:negative regulation of insulin secretion; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro.
103Q9Y6E7    314   SIR4_HUMAN NAD-dependent protein deacetylase ...2240.0000000000001     75.5     29     47GO:0005759; C:mitochondrial matrix; IDA:UniProtKB.
GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006342; P:chromatin silencing; TAS:ProtInc.::GO:0046676; P:negative regulation of insulin secretion; IMP:UniProtKB.::GO:0006471; P:protein ADP-ribosylation; TAS:BHF-UCL.::GO:0006476; P:protein deacetylation; IEA:InterPro.
104Q6MJJ2    235   NPD_BDEBA NAD-dependent protein deacylase OS=...2640.0000000000001     74.3     28     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
105Q89LY4    254   NPD1_BRAJA NAD-dependent protein deacetylase ...2890.0000000000002     73.9     25     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
106Q5WKC8    237   NPD_BACSK NAD-dependent protein deacetylase O...2540.0000000000002     73.9     25     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
107Q8R9N6    242   NPD1_THETN NAD-dependent protein deacylase 1 ...2290.0000000000002     73.6     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
108Q8NSM4    258   NPD_CORGL NAD-dependent protein deacylase OS=...2460.0000000000002     73.6     26     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
109A8MBU4    257   NPD_CALMQ NAD-dependent protein deacetylase O...2450.0000000000002     73.6     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
110Q974M6    250   NPD_SULTO NAD-dependent protein deacetylase O...2350.0000000000002     73.6     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
111A0QDH4    282   NPD1_MYCA1 NAD-dependent protein deacetylase ...2490.0000000000003     73.6     25     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0019213; F:deacetylase activity; IEA:HAMAP.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:HAMAP.
GO:0006476; P:protein deacetylation; IEA:InterPro.
112Q885X7    248   NPD2_PSESM NAD-dependent protein deacylase 2 ...2360.0000000000005     72.4     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
113Q5AI90    306   SIR5_CANAL NAD-dependent protein deacylase OS...2630.0000000000006     72.8     26     41
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
114Q94AQ6    373   SIR4_ARATH NAD-dependent protein deacetylase ...2490.0000000000007     73.6     26     41GO:0005634; C:nucleus; IDA:TAIR.
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042742; P:defense response to bacterium; IMP:TAIR.::GO:0031348; P:negative regulation of defense response; IMP:TAIR.::GO:0006476; P:protein deacetylation; IEA:InterPro.
115Q6N6U0    253   NPD_RHOPA NAD-dependent protein deacetylase O...2350.0000000000008     72     26     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
116Q5L014    242   NPD1_GEOKA NAD-dependent protein deacetylase ...2350.000000000001     71.2     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
117Q9KEE5    237   NPD_BACHD NAD-dependent protein deacetylase O...2660.000000000001     70.9     25     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
118Q607X6    255   NPD_METCA NAD-dependent protein deacylase OS=...2490.000000000002     70.9     29     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
119Q20481    287   SIR42_CAEEL NAD-dependent protein deacetylase...2490.000000000002     71.2     27     45
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0040011; P:locomotion; IMP:WormBase.::GO:0006476; P:protein deacetylation; IEA:InterPro.
120Q7UFQ9    239   NPD_RHOBA NAD-dependent protein deacylase OS=...2620.000000000002     70.5     28     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
121Q97VX5    247   NPD_SULSO NAD-dependent protein deacetylase O...2320.000000000002     70.5     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
records
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