| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q08227 | 384 | INP54_YEAST Phosphatidylinositol 4,5-bisphosp... | 384 | 0 | 797 | 100 | 100 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:SGD. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:SGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 2 | O43001 | 1076 | SYJ1_SCHPO Inositol-1,4,5-trisphosphate 5-pho... | 326 | 2e-20 | 97.1 | 29 | 43 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IDA:PomBase.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC. | | | | | | | | | | GO:0006897; P:endocytosis; NAS:PomBase.::GO:0048017; P:inositol lipid-mediated signaling; IC:PomBase.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:PomBase.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 3 | P40559 | 946 | INP51_YEAST Phosphatidylinositol 4,5-bisphosp... | 319 | 4e-20 | 95.9 | 28 | 42 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:SGD. | | | | | | | | | | GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:SGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 4 | P50942 | 1183 | INP52_YEAST Polyphosphatidylinositol phosphat... | 328 | 2e-18 | 90.9 | 28 | 43 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0042598; C:vesicular fraction; IDA:SGD. | | | | | | | | | | GO:0043813; F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:SGD.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0043812; F:phosphatidylinositol-4-phosphate phosphatase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:SGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 5 | Q6P549 | 1257 | SHIP2_MOUSE Phosphatidylinositol 3,4,5-trisph... | 245 | 0.00000000000002 | 78.6 | 30 | 45 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; IDA:MGI.::GO:0010629; P:negative regulation of gene expression; IMP:MGI.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0032868; P:response to insulin stimulus; IMP:MGI. | 6 | Q9WVR3 | 1257 | SHIP2_RAT Phosphatidylinositol 3,4,5-trisphos... | 245 | 0.00000000000002 | 78.6 | 30 | 45 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:RGD. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IDA:RGD.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:RGD.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0032957; P:inositol trisphosphate metabolic process; IDA:RGD.::GO:0008156; P:negative regulation of DNA replication; IMP:RGD.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:RGD.::GO:0043569; P:negative regulation of insulin-like growth factor receptor signaling pathway; IMP:RGD.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:RGD.::GO:0010977; P:negative regulation of neuron projection development; IMP:RGD.::GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; IMP:RGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0042493; P:response to drug; IEP:RGD. | 7 | Q2I6J1 | 1266 | SHP2A_DANRE Phosphatidylinositol 3,4,5-trisph... | 242 | 0.00000000000003 | 78.2 | 29 | 46 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030509; P:BMP signaling pathway; IMP:ZFIN.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0040037; P:negative regulation of fibroblast growth factor receptor signaling pathway; IMP:ZFIN.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 8 | Q12271 | 1107 | INP53_YEAST Polyphosphatidylinositol phosphat... | 292 | 0.00000000000005 | 77.4 | 27 | 42 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0042598; C:vesicular fraction; IDA:SGD. | | | | | | | | | | GO:0043813; F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:SGD.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0043812; F:phosphatidylinositol-4-phosphate phosphatase activity; IDA:SGD. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:SGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 9 | O15357 | 1258 | SHIP2_HUMAN Phosphatidylinositol 3,4,5-trisph... | 245 | 0.00000000000008 | 77 | 30 | 44 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:UniProtKB.::GO:0007155; P:cell adhesion; TAS:UniProtKB.::GO:0006897; P:endocytosis; IMP:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 10 | Q84MA2 | 590 | IP5P1_ARATH Type I inositol 1,4,5-trisphospha... | 209 | 0.0000000000003 | 74.7 | 27 | 47 | | | | | | | | | | | GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:EC.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IDA:TAIR. | | | | | | | | | | GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:TAIR.::GO:0032957; P:inositol trisphosphate metabolic process; IDA:TAIR.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 11 | O15056 | 1496 | SYNJ2_HUMAN Synaptojanin-2 OS=Homo sapiens (H... | 246 | 0.0000000000004 | 74.7 | 26 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 12 | Q5EAF2 | 334 | IP5PB_ARATH Type I inositol 1,4,5-trisphospha... | 284 | 0.0000000000009 | 72 | 25 | 43 | | | | | | | | | | | GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:EC.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:EC.::GO:0034485; F:phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity; IDA:TAIR.::GO:0043813; F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; IDA:TAIR.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:TAIR. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:TAIR.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0009737; P:response to abscisic acid stimulus; IEP:TAIR.::GO:0009733; P:response to auxin stimulus; IEP:TAIR.::GO:0009753; P:response to jasmonic acid stimulus; IEP:TAIR. | 13 | Q9SYK4 | 1136 | IP5PD_ARATH Type I inositol 1,4,5-trisphospha... | 145 | 0.000000000009 | 70.5 | 31 | 52 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IDA:TAIR.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010252; P:auxin homeostasis; IMP:TAIR.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:TAIR.::GO:0010087; P:phloem or xylem histogenesis; IMP:TAIR.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.::GO:0009637; P:response to blue light; IEP:TAIR.::GO:0007584; P:response to nutrient; IMP:TAIR.::GO:0009611; P:response to wounding; IEP:TAIR.::GO:0048364; P:root development; IMP:TAIR.::GO:0010182; P:sugar mediated signaling pathway; IMP:TAIR. | 14 | Q9ES52 | 1191 | SHIP1_MOUSE Phosphatidylinositol 3,4,5-trisph... | 299 | 0.00000000001 | 70.1 | 26 | 45 | GO:0005622; C:intracellular; IMP:GOC.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IDA:MGI.::GO:0034594; F:phosphatidylinositol trisphosphate phosphatase activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0051425; F:PTB domain binding; IDA:MGI.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008340; P:determination of adult lifespan; IMP:MGI.::GO:0016064; P:immunoglobulin mediated immune response; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IMP:MGI.::GO:0050869; P:negative regulation of B cell activation; IMP:MGI.::GO:0030889; P:negative regulation of B cell proliferation; IMP:MGI.::GO:0045779; P:negative regulation of bone resorption; IMP:MGI.::GO:0050777; P:negative regulation of immune response; IMP:MGI.::GO:0045409; P:negative regulation of interleukin-6 biosynthetic process; IMP:MGI.::GO:0045656; P:negative regulation of monocyte differentiation; IMP:MGI.::GO:0045659; P:negative regulation of neutrophil differentiation; IMP:MGI.::GO:0045671; P:negative regulation of osteoclast differentiation; IMP:MGI.::GO:0009968; P:negative regulation of signal transduction; IMP:MGI.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0045579; P:positive regulation of B cell differentiation; IMP:MGI.::GO:0045648; P:positive regulation of erythrocyte differentiation; IMP:MGI. | 15 | Q8CHC4 | 1574 | SYNJ1_MOUSE Synaptojanin-1 OS=Mus musculus (M... | 253 | 0.00000000001 | 70.1 | 25 | 41 | GO:0030118; C:clathrin coat; TAS:MGI. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IMP:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046855; P:inositol phosphate dephosphorylation; IMP:MGI.::GO:0007612; P:learning; IMP:MGI.::GO:0046856; P:phosphatidylinositol dephosphorylation; IMP:MGI.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:MGI.::GO:0016082; P:synaptic vesicle priming; IMP:MGI.::GO:0016191; P:synaptic vesicle uncoating; IMP:MGI. | 16 | Q62910 | 1574 | SYNJ1_RAT Synaptojanin-1 OS=Rattus norvegicus... | 253 | 0.00000000001 | 70.1 | 25 | 41 | GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IDA:RGD. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0014015; P:positive regulation of gliogenesis; IMP:RGD.::GO:0048260; P:positive regulation of receptor-mediated endocytosis; IMP:RGD.::GO:0034097; P:response to cytokine stimulus; IMP:RGD.::GO:0032526; P:response to retinoic acid; IMP:RGD. | 17 | Q84W55 | 1101 | IP5P4_ARATH Type II inositol 1,4,5-trisphosph... | 151 | 0.00000000001 | 69.7 | 31 | 48 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 18 | Q6P4S2 | 1019 | SHIP1_XENLA Phosphatidylinositol 3,4,5-trisph... | 272 | 0.00000000002 | 69.7 | 29 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 19 | Q9LR47 | 617 | IP5P3_ARATH Type I inositol 1,4,5-trisphospha... | 211 | 0.00000000002 | 69.3 | 30 | 43 | | | | | | | | | | | GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:EC.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:EC. | | | | | | | | | | GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0010588; P:cotyledon vascular tissue pattern formation; IMP:TAIR.::GO:0046855; P:inositol phosphate dephosphorylation; IMP:TAIR.::GO:0048016; P:inositol phosphate-mediated signaling; IC:TAIR.::GO:0032957; P:inositol trisphosphate metabolic process; IMP:TAIR.::GO:0010305; P:leaf vascular tissue pattern formation; IMP:TAIR.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0010067; P:procambium histogenesis; IMP:TAIR. | 20 | P97573 | 1190 | SHIP1_RAT Phosphatidylinositol 3,4,5-trisphos... | 299 | 0.00000000003 | 68.9 | 25 | 45 | GO:0005884; C:actin filament; IDA:RGD.::GO:0030863; C:cortical cytoskeleton; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0030487; F:inositol-4,5-bisphosphate 5-phosphatase activity; IDA:RGD.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 21 | Q9D2G5 | 1434 | SYNJ2_MOUSE Synaptojanin-2 OS=Mus musculus (M... | 246 | 0.00000000004 | 68.6 | 24 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 22 | O55207 | 1496 | SYNJ2_RAT Synaptojanin-2 OS=Rattus norvegicus... | 246 | 0.00000000005 | 68.2 | 25 | 43 | GO:0043679; C:axon terminus; IDA:RGD.::GO:0005881; C:cytoplasmic microtubule; IDA:RGD.::GO:0031315; C:extrinsic to mitochondrial outer membrane; IDA:RGD.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0032587; C:ruffle membrane; IDA:RGD. | | | | | | | | | | GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0052744; F:phosphatidylinositol monophosphate phosphatase activity; IDA:RGD.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IPI:RGD. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:RGD.::GO:0048312; P:intracellular distribution of mitochondria; IDA:RGD.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:RGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 23 | Q9FUR2 | 646 | IP5P2_ARATH Type I inositol 1,4,5-trisphospha... | 98 | 0.03 | 40 | 29 | 49 | | | | | | | | | | | GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:EC.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IDA:TAIR. | | | | | | | | | | GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:TAIR.::GO:0032957; P:inositol trisphosphate metabolic process; IMP:TAIR.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0009845; P:seed germination; IMP:TAIR. | 24 | O43426 | 1573 | SYNJ1_HUMAN Synaptojanin-1 OS=Homo sapiens (H... | 253 | 0.00000000006 | 68.2 | 25 | 40 | | | | | | | | | | | GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 25 | O18964 | 1324 | SYNJ1_BOVIN Synaptojanin-1 OS=Bos taurus (Bov... | 253 | 0.00000000007 | 67.8 | 25 | 40 | GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 26 | Q9USQ6 | 889 | SYJ2_SCHPO Inositol-1,4,5-trisphosphate 5-pho... | 323 | 0.0000000002 | 65.9 | 24 | 42 | GO:0005737; C:cytoplasm; IDA:PomBase. | | | | | | | | | | GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; ISS:PomBase.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC. | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.::GO:0048017; P:inositol lipid-mediated signaling; IC:PomBase.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:PomBase.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 27 | Q9JMC1 | 1001 | PI5PA_RAT Phosphatidylinositol 4,5-bisphospha... | 344 | 0.0000000002 | 65.9 | 25 | 42 | GO:0005737; C:cytoplasm; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0001726; C:ruffle; IDA:RGD. | | | | | | | | | | GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:EC.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IDA:RGD.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0031115; P:negative regulation of microtubule polymerization; IMP:RGD.::GO:0010977; P:negative regulation of neuron projection development; IMP:RGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 28 | P59644 | 1003 | PI5PA_MOUSE Phosphatidylinositol 4,5-bisphosp... | 344 | 0.0000000003 | 65.9 | 24 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043198; C:dendritic shaft; IDA:MGI.::GO:0030426; C:growth cone; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:EC.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:EC.::GO:0034485; F:phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010977; P:negative regulation of neuron projection development; IMP:MGI.::GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IMP:MGI.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 29 | Q8C5L6 | 468 | INP5K_MOUSE Inositol polyphosphate 5-phosphat... | 193 | 0.0000000003 | 65.1 | 30 | 44 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0043005; C:neuron projection; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0032587; C:ruffle membrane; ISS:UniProtKB.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB. | | | | | | | | | | GO:0016312; F:inositol bisphosphate phosphatase activity; IMP:UniProtKB.::GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:EC.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:EC.::GO:0034485; F:phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity; IDA:UniProtKB.::GO:0005000; F:vasopressin receptor activity; IDA:UniProtKB. | | | | | | | | | | GO:0071320; P:cellular response to cAMP; IDA:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0032869; P:cellular response to insulin stimulus; ISS:UniProtKB.::GO:0071356; P:cellular response to tumor necrosis factor; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0043922; P:negative regulation by host of viral transcription; ISS:UniProtKB.::GO:0051926; P:negative regulation of calcium ion transport; ISS:UniProtKB.::GO:0035305; P:negative regulation of dephosphorylation; IMP:UniProtKB.::GO:0010829; P:negative regulation of glucose transport; ISS:UniProtKB.::GO:2000466; P:negative regulation of glycogen (starch) synthase activity; IMP:UniProtKB.::GO:0045719; P:negative regulation of glycogen biosynthetic process; IMP:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; ISS:UniProtKB.::GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IMP:UniProtKB.::GO:0010801; P:negative regulation of peptidyl-threonine phosphorylation; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0090315; P:negative regulation of protein targeting to membrane; ISS:UniProtKB.::GO:0045869; P:negative regulation of retroviral genome replication; ISS:UniProtKB.::GO:0051497; P:negative regulation of stress fiber assembly; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:2001153; P:positive regulation of renal water transport; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0035810; P:positive regulation of urine volume; IDA:UniProtKB.::GO:0072661; P:protein targeting to plasma membrane; IDA:UniProtKB.::GO:0097178; P:ruffle assembly; ISS:UniProtKB. | 30 | Q9SKB7 | 1144 | IP5PE_ARATH Type II inositol 1,4,5-trisphosph... | 140 | 0.0000000004 | 65.5 | 31 | 51 | | | | | | | | | | | GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IDA:TAIR.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0034485; F:phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity; IDA:TAIR.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:TAIR. | | | | | | | | | | GO:0046855; P:inositol phosphate dephosphorylation; IDA:TAIR.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 31 | Q92835 | 1189 | SHIP1_HUMAN Phosphatidylinositol 3,4,5-trisph... | 299 | 0.0000000006 | 64.7 | 25 | 45 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. |
