Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL065C
Length:
384
Number of sequences:
5887
Description:
YOL065C INP54 SGDID:S000005426, Chr XV from 205885-204731, Genome Release 64-1-1, reverse complement, Verified ORF, "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase with a role in secretion, localizes to the endoplasmic reticulum via the C-terminal tail; lacks the Sac1 domain and proline-rich region found in the other 3 INP proteins"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q92835    1189   SHIP1_HUMAN Phosphatidylinositol 3,4,5-trisph...2990.0000000006     64.7     25     45GO:0005829; C:cytosol; TAS:Reactome.
GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
32O80560    1305   IP5PC_ARATH Type I inositol 1,4,5-trisphospha...1090.0000000007     64.7     31     55
GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IDA:TAIR.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0046855; P:inositol phosphate dephosphorylation; IDA:TAIR.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
33Q9NRR6    644   INP5E_HUMAN 72 kDa inositol polyphosphate 5-p...1800.000000004     62     30     48GO:0035085; C:cilium axoneme; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; TAS:UniProtKB.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.
GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
34A0FI79    644   INP5E_PANTR 72 kDa inositol polyphosphate 5-p...1800.000000004     62     30     48GO:0035085; C:cilium axoneme; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.
GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
35P34370    398   YLJ7_CAEEL Uncharacterized protein C50C3.7 OS...1650.000000005     61.2     31     42
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
36Q15735    1006   PI5PA_HUMAN Phosphatidylinositol 4,5-bisphosp...2070.00000001     60.8     29     46GO:0005737; C:cytoplasm; IDA:MGI.::GO:0001726; C:ruffle; IDA:MGI.
GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:EC.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:EC.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
37Q8K337    993   I5P2_MOUSE Type II inositol 1,4,5-trisphospha...2020.00000001     60.8     30     42GO:0005829; C:cytosol; IDA:MGI.::GO:0016021; C:integral to membrane; IDA:MGI.
GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IDA:UniProtKB.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:UniProtKB.
GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0070613; P:regulation of protein processing; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0030317; P:sperm motility; IMP:MGI.::GO:0007283; P:spermatogenesis; IMP:MGI.
38Q9BT40    448   INP5K_HUMAN Inositol polyphosphate 5-phosphat...1910.00000002     59.3     27     43GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0043005; C:neuron projection; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0032587; C:ruffle membrane; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB.
GO:0016312; F:inositol bisphosphate phosphatase activity; IDA:UniProtKB.::GO:0046030; F:inositol trisphosphate phosphatase activity; IDA:MGI.::GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:EC.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:EC.::GO:0042577; F:lipid phosphatase activity; NAS:UniProtKB.::GO:0034485; F:phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005000; F:vasopressin receptor activity; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.::GO:0071320; P:cellular response to cAMP; ISS:UniProtKB.::GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:UniProtKB.::GO:0032869; P:cellular response to insulin stimulus; IDA:UniProtKB.::GO:0071356; P:cellular response to tumor necrosis factor; IDA:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:MGI.::GO:0043922; P:negative regulation by host of viral transcription; IDA:UniProtKB.::GO:0051926; P:negative regulation of calcium ion transport; IDA:UniProtKB.::GO:0035305; P:negative regulation of dephosphorylation; ISS:UniProtKB.::GO:0010829; P:negative regulation of glucose transport; IDA:UniProtKB.::GO:2000466; P:negative regulation of glycogen (starch) synthase activity; ISS:UniProtKB.::GO:0045719; P:negative regulation of glycogen biosynthetic process; IDA:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.::GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0010801; P:negative regulation of peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0090315; P:negative regulation of protein targeting to membrane; IDA:UniProtKB.::GO:0045869; P:negative regulation of retroviral genome replication; IDA:UniProtKB.::GO:0051497; P:negative regulation of stress fiber assembly; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:2001153; P:positive regulation of renal water transport; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0035810; P:positive regulation of urine volume; ISS:UniProtKB.::GO:0072661; P:protein targeting to plasma membrane; ISS:UniProtKB.::GO:0097178; P:ruffle assembly; IDA:UniProtKB.
39P32019    993   I5P2_HUMAN Type II inositol 1,4,5-trisphospha...1920.00000003     59.3     29     44GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0016020; C:membrane; IDA:UniProtKB.::GO:0015630; C:microtubule cytoskeleton; IDA:HPA.
GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IDA:UniProtKB.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
40Q9WVR1    647   INP5E_RAT 72 kDa inositol polyphosphate 5-pho...1860.00000007     58.2     29     46GO:0035085; C:cilium axoneme; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:RGD.
GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IMP:RGD.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.
GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0010976; P:positive regulation of neuron projection development; IMP:RGD.
41O14306    1191   YE8A_SCHPO Probable inositol polyphosphate 5-...3600.0000001     57.8     22     41GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; ISS:PomBase.
GO:0006897; P:endocytosis; ISS:PomBase.::GO:0031505; P:fungal-type cell wall organization; ISS:PomBase.::GO:0048017; P:inositol lipid-mediated signaling; IC:PomBase.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:PomBase.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
42Q9JII1    647   INP5E_MOUSE 72 kDa inositol polyphosphate 5-p...1800.0000001     57.4     28     47GO:0035085; C:cilium axoneme; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:MGI.
GO:0046855; P:inositol phosphate dephosphorylation; IDA:MGI.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:MGI.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
43Q01968    901   OCRL_HUMAN Inositol polyphosphate 5-phosphata...2830.0000006     55.5     25     42GO:0030136; C:clathrin-coated vesicle; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0005795; C:Golgi stack; TAS:ProtInc.::GO:0005798; C:Golgi-associated vesicle; TAS:ProtInc.
GO:0004437; F:inositol or phosphatidylinositol phosphatase activity; TAS:ProtInc.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
44Q2I6J0    1226   SHP2B_DANRE Phosphatidylinositol 3,4,5-trisph...2690.000001     54.7     24     39GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
45Q14642    412   I5P1_HUMAN Type I inositol 1,4,5-trisphosphat...840.0003     46.2     32     45GO:0016020; C:membrane; NAS:UniProtKB.
GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:EC.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; NAS:UniProtKB.::GO:0042731; F:PH domain binding; IPI:BHF-UCL.
GO:0007154; P:cell communication; NAS:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
46Q29467    412   I5P1_CANFA Type I inositol 1,4,5-trisphosphat...840.002     43.5     30     44GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:EC.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:EC.
GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
47Q17848    409   I5P1_CAEEL Probable type I inositol 1,4,5-tri...1270.006     42     28     44
GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:EC.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:EC.
GO:0007173; P:epidermal growth factor receptor signaling pathway; IGI:WormBase.::GO:0048016; P:inositol phosphate-mediated signaling; IGI:WormBase.::GO:0030728; P:ovulation; IMP:WormBase.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:WormBase.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
48Q6C6I3    304   S2538_YARLI Solute carrier family 25 member 3...1921.6     34.3     25     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0006810; P:transport; IEA:UniProtKB-KW.
records
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