Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL061W
Length:
496
Number of sequences:
5887
Description:
YOL061W PRS5 SGDID:S000005422, Chr XV from 212244-213734, Genome Release 64-1-1, Verified ORF, "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q12265    496   KPR5_YEAST Ribose-phosphate pyrophosphokinase...4960     1023     100     100GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IPI:SGD.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
2P87171    341   KPR5_SCHPO Ribose-phosphate pyrophosphokinase...1681e-33     134     44     61GO:0005737; C:cytoplasm; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:PomBase.
GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; ISS:PomBase.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0006163; P:purine nucleotide metabolic process; NAS:PomBase.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
3O60256    369   KPRB_HUMAN Phosphoribosyl pyrophosphate synth...970.000000000000007     79.7     42     64
GO:0004857; F:enzyme inhibitor activity; TAS:ProtInc.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
4Q14558    356   KPRA_HUMAN Phosphoribosyl pyrophosphate synth...840.0000000001     66.6     40     61
GO:0004857; F:enzyme inhibitor activity; TAS:ProtInc.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
5Q9D0M1    356   KPRA_MOUSE Phosphoribosyl pyrophosphate synth...840.0000000001     66.6     40     61
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
6Q08DW2    356   KPRA_BOVIN Phosphoribosyl pyrophosphate synth...840.0000000002     66.2     40     61
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
7O08618    369   KPRB_RAT Phosphoribosyl pyrophosphate synthas...970.000000000000007     79.7     42     64GO:0002189; C:ribose phosphate diphosphokinase complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
8Q8R574    369   KPRB_MOUSE Phosphoribosyl pyrophosphate synth...970.000000000000009     79.3     42     64
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
9Q63468    356   KPRA_RAT Phosphoribosyl pyrophosphate synthas...840.0000000001     66.6     40     61GO:0002189; C:ribose phosphate diphosphokinase complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0030234; F:enzyme regulator activity; IMP:RGD.::GO:0019900; F:kinase binding; IPI:RGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
GO:0033673; P:negative regulation of kinase activity; IDA:RGD.::GO:0009165; P:nucleotide biosynthetic process; TAS:RGD.
10Q5RBA8    369   KPRB_PONAB Phosphoribosyl pyrophosphate synth...970.000000000000008     79.3     42     64
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
11Q28DH0    358   KPRB_XENTR Phosphoribosyl pyrophosphate synth...970.000000000000009     79.3     40     65
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
12Q5ZL26    369   KPRB_CHICK Phosphoribosyl pyrophosphate synth...970.00000000000002     78.6     41     64
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
13A2VDS0    369   KPRB_BOVIN Phosphoribosyl pyrophosphate synth...970.00000000000003     77.8     41     64
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
14P41831    409   KPR1_SCHPO Ribose-phosphate pyrophosphokinase...974e-28     119     57     73GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:PomBase.
GO:0006163; P:purine nucleotide metabolic process; NAS:PomBase.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
15Q81J97    317   KPRS_BACCR Ribose-phosphate pyrophosphokinase...960.000000000000002     80.5     43     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
16Q81VZ0    317   KPRS_BACAN Ribose-phosphate pyrophosphokinase...960.000000000000002     80.5     43     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
17Q82TQ4    316   KPRS_NITEU Ribose-phosphate pyrophosphokinase...1185e-21     97.1     39     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
18O33924    317   KPRS_CORAM Ribose-phosphate pyrophosphokinase...960.000000000000002     80.5     43     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
19Q8K9X2    315   KPRS_BUCAP Ribose-phosphate pyrophosphokinase...1117e-20     94     41     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
20P14193    317   KPRS_BACSU Ribose-phosphate pyrophosphokinase...950.000000000000003     80.1     41     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
21Q8EU34    317   KPRS_OCEIH Ribose-phosphate pyrophosphokinase...962e-18     89.7     47     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
22Q83YI7    318   KPRS1_LISIV Ribose-phosphate pyrophosphokinas...920.00000000000007     75.9     42     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
23Q97E93    319   KPRS_CLOAB Ribose-phosphate pyrophosphokinase...955e-20     94.4     45     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
24Q83TK1    318   KPRS1_LISWE Ribose-phosphate pyrophosphokinas...920.00000000000006     76.3     42     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
25Q48793    318   KPRS1_LISMO Ribose-phosphate pyrophosphokinas...920.00000000000007     75.9     42     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
26Q724L4    318   KPRS1_LISMF Ribose-phosphate pyrophosphokinas...920.00000000000007     75.9     42     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
27Q92F68    318   KPRS1_LISIN Ribose-phosphate pyrophosphokinas...920.00000000000006     76.3     42     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
28O94413    321   KPR2_SCHPO Ribose-phosphate pyrophosphokinase...996e-26     111     47     76GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:PomBase.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0006163; P:purine nucleotide metabolic process; NAS:PomBase.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
29Q88PX6    313   KPRS_PSEPK Ribose-phosphate pyrophosphokinase...1078e-22     99.4     43     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
30P42816    315   KPRS_BACCL Ribose-phosphate pyrophosphokinase...920.000000000000009     78.6     42     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
31Q5XGI0    318   PRPS2_XENTR Ribose-phosphate pyrophosphokinas...976e-28     117     58     74
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
records
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