Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL054W
Length:
406
Number of sequences:
5887
Description:
YOL054W PSH1 SGDID:S000005415, Chr XV from 228614-229834, Genome Release 64-1-1, Verified ORF, "E3 ubiquitin ligase that mediates poyubiquitination and degradation of centromere-binding protein Cse4p and prevents Cse4p from mislocalizing to euchromatin; ubiquitylation of Cse4p may be antagonized by Scm3p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
361Q2PFU6    360   RN146_MACFA E3 ubiquitin-protein ligase RNF14...480.41     36.2     31     44GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
362Q3UF64    445   RNFT2_MOUSE RING finger and transmembrane dom...450.43     36.6     40     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
363D2H0Y8    359   RN146_AILME E3 ubiquitin-protein ligase RNF14...480.44     36.2     31     44GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
364O60858    407   TRI13_HUMAN E3 ubiquitin-protein ligase TRIM1...770.44     36.2     32     44GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0097038; C:perinuclear endoplasmic reticulum; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.::GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.::GO:0010942; P:positive regulation of cell death; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0016239; P:positive regulation of macroautophagy; IDA:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0010332; P:response to gamma radiation; IEP:UniProtKB.
365Q5XIH6    364   TRI54_RAT Tripartite motif-containing protein...630.44     36.2     32     43GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
366Q9NTX7    359   RN146_HUMAN E3 ubiquitin-protein ligase RNF14...480.44     36.2     31     44GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0072572; F:poly-ADP-D-ribose binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IMP:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
367Q5REJ9    358   TRI54_PONAB Tripartite motif-containing prote...630.44     36.2     32     43GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
368O70418    631   RN112_RAT RING finger protein 112 OS=Rattus n...470.45     36.6     36     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; NAS:RGD.
369Q9BYV2    358   TRI54_HUMAN Tripartite motif-containing prote...630.46     36.2     32     43GO:0005874; C:microtubule; NAS:UniProtKB.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0004871; F:signal transducer activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007017; P:microtubule-based process; NAS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007026; P:negative regulation of microtubule depolymerization; NAS:UniProtKB.
370Q5REL3    358   RN146_PONAB E3 ubiquitin-protein ligase RNF14...480.46     36.2     31     44GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
371Q6IV56    222   RN141_DANRE RING finger protein 141 OS=Danio ...480.46     35.8     31     48
GO:0008270; F:zinc ion binding; IEA:InterPro.
372Q6ZMU5    477   TRI72_HUMAN Tripartite motif-containing prote...700.46     36.2     31     47GO:0030659; C:cytoplasmic vesicle membrane; ISS:UniProtKB.::GO:0042383; C:sarcolemma; ISS:UniProtKB.
GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; ISS:UniProtKB.::GO:0003012; P:muscle system process; ISS:UniProtKB.::GO:0001778; P:plasma membrane repair; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
373Q0IJ20    695   RN145_XENTR RING finger protein 145 OS=Xenopu...500.48     36.6     32     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
374P22682    913   CBL_MOUSE E3 ubiquitin-protein ligase CBL OS=...320.5     36.6     47     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045453; P:bone resorption; ISS:UniProtKB.::GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
375Q13191    982   CBLB_HUMAN E3 ubiquitin-protein ligase CBL-B ...320.51     36.6     47     53
376Q5BIY5    695   RN145_XENLA RING finger protein 145 OS=Xenopu...500.51     36.2     32     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
377Q3TTA7    982   CBLB_MOUSE E3 ubiquitin-protein ligase CBL-B ...320.51     36.6     47     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0006955; P:immune response; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IMP:MGI.::GO:0046642; P:negative regulation of alpha-beta T cell proliferation; IMP:MGI.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IMP:MGI.::GO:0045732; P:positive regulation of protein catabolic process; IMP:MGI.::GO:0002669; P:positive regulation of T cell anergy; IMP:MGI.::GO:0042110; P:T cell activation; IMP:MGI.
378A6NDQ2    463   TRIX3_HUMAN Tripartite motif-containing prote...370.52     36.2     38     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
379A0JPQ4    477   TRI72_RAT Tripartite motif-containing protein...700.52     36.2     33     49GO:0030659; C:cytoplasmic vesicle membrane; ISS:UniProtKB.::GO:0042383; C:sarcolemma; ISS:UniProtKB.
GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; ISS:UniProtKB.::GO:0003012; P:muscle system process; ISS:UniProtKB.::GO:0001778; P:plasma membrane repair; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
380Q5XIK5    352   RN146_RAT E3 ubiquitin-protein ligase RNF146 ...480.52     35.8     31     44GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
381Q8K4S7    938   CBLB_RAT E3 ubiquitin-protein ligase CBL-B OS...320.53     36.2     47     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0023051; P:regulation of signaling; IEA:InterPro.::GO:0009629; P:response to gravity; IEP:RGD.::GO:0009725; P:response to hormone stimulus; IEP:RGD.
382Q9CZW6    359   RN146_MOUSE E3 ubiquitin-protein ligase RNF14...480.53     35.8     31     44GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
383Q6GQL0    918   CBLBA_XENLA E3 ubiquitin-protein ligase CBL-B...320.55     36.2     47     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0023051; P:regulation of signaling; IEA:InterPro.
384P30631    161   YOUD_CAEEL Uncharacterized RING finger protei...370.55     35     32     49
GO:0008270; F:zinc ion binding; IEA:InterPro.
385Q4P400    355   CWC24_USTMA Pre-mRNA-splicing factor CWC24 OS...430.56     35.8     37     47GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
386Q58D15    366   TRI54_BOVIN Tripartite motif-containing prote...630.57     35.8     32     43GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
387Q9SPL2    334   CIP8_ARATH E3 ubiquitin-protein ligase CIP8 O...530.57     35.8     32     47GO:0005737; C:cytoplasm; IDA:TAIR.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016567; P:protein ubiquitination; IDA:TAIR.
388Q9LT17    340   BBR_ARATH E3 ubiquitin ligase BIG BROTHER-rel...370.57     35.8     32     54
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
389Q6DFR2    982   CBLB_XENTR E3 ubiquitin-protein ligase CBL-B ...320.58     36.2     47     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0023051; P:regulation of signaling; IEA:InterPro.
390P22681    906   CBL_HUMAN E3 ubiquitin-protein ligase CBL OS=...320.58     36.2     47     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:HGNC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:HGNC.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:BHF-UCL.::GO:0048260; P:positive regulation of receptor-mediated endocytosis; TAS:HGNC.
391Q5EBN2    209   TRI61_HUMAN Putative tripartite motif-contain...430.58     35.4     37     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
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