Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL054W
Length:
406
Number of sequences:
5887
Description:
YOL054W PSH1 SGDID:S000005415, Chr XV from 228614-229834, Genome Release 64-1-1, Verified ORF, "E3 ubiquitin ligase that mediates poyubiquitination and degradation of centromere-binding protein Cse4p and prevents Cse4p from mislocalizing to euchromatin; ubiquitylation of Cse4p may be antagonized by Scm3p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
331Q80V85    475   TRI62_MOUSE Tripartite motif-containing prote...690.24     37.4     33     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
332Q5NCC3    630   TRI41_MOUSE E3 ubiquitin-protein ligase TRIM4...300.24     37.4     47     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
333O14212    470   YDT7_SCHPO Uncharacterized RING finger protei...560.25     37.4     34     46GO:0005829; C:cytosol; IDA:PomBase.
GO:0008270; F:zinc ion binding; IEA:InterPro.
334Q06436    670   MAG2_YEAST RING-finger protein MAG2 OS=Saccha...710.26     37.4     32     42GO:0005737; C:cytoplasm; IDA:SGD.
GO:0008270; F:zinc ion binding; IEA:InterPro.
335P38398    1863   BRCA1_HUMAN Breast cancer type 1 susceptibili...570.26     37.4     35     54GO:0070531; C:BRCA1-A complex; IDA:UniProtKB.::GO:0031436; C:BRCA1-BARD1 complex; IDA:UniProtKB.::GO:0008274; C:gamma-tubulin ring complex; NAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.::GO:0030529; C:ribonucleoprotein complex; IDA:MGI.::GO:0001726; C:ruffle; IDA:BHF-UCL.
GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IDA:MGI.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0015631; F:tubulin binding; NAS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0071681; P:cellular response to indole-3-methanol; IDA:UniProtKB.::GO:0007059; P:chromosome segregation; IMP:UniProtKB.::GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; TAS:UniProtKB.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IDA:MGI.::GO:0000724; P:double-strand break repair via homologous recombination; IDA:HGNC.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0046600; P:negative regulation of centriole replication; NAS:UniProtKB.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; IMP:UniProtKB.::GO:0051573; P:negative regulation of histone H3-K9 methylation; IDA:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0071158; P:positive regulation of cell cycle arrest; IDA:BHF-UCL.::GO:0045739; P:positive regulation of DNA repair; IMP:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; IDA:BHF-UCL.::GO:2000617; P:positive regulation of histone H3-K9 acetylation; IDA:BHF-UCL.::GO:2000620; P:positive regulation of histone H4-K16 acetylation; IDA:BHF-UCL.::GO:0070512; P:positive regulation of histone H4-K20 methylation; IDA:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006301; P:postreplication repair; IDA:HGNC.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:2000145; P:regulation of cell motility; IDA:BHF-UCL.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:0006359; P:regulation of transcription from RNA polymerase III promoter; TAS:UniProtKB.::GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:BHF-UCL.
336P97868    1790   RBBP6_MOUSE E3 ubiquitin-protein ligase RBBP6...490.27     37.4     37     53GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
337Q753V5    1085   RAD5_ASHGO DNA repair protein RAD5 OS=Y-1056)...570.28     37.4     33     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
338Q09268    610   YQDA_CAEEL Uncharacterized RING finger protei...500.28     37     26     50
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
339Q6J6J0    1863   BRCA1_PONPY Breast cancer type 1 susceptibili...570.28     37.4     35     54GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.
340Q6J6I9    1863   BRCA1_MACMU Breast cancer type 1 susceptibili...570.28     37.4     35     54GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.
341Q7Z6E9    1792   RBBP6_HUMAN E3 ubiquitin-protein ligase RBBP6...490.28     37.4     37     53GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
342Q9GKK8    1863   BRCA1_PANTR Breast cancer type 1 susceptibili...570.29     37.4     35     54GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.::GO:0008274; C:gamma-tubulin ring complex; NAS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0015631; F:tubulin binding; NAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; TAS:UniProtKB.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0046600; P:negative regulation of centriole replication; NAS:UniProtKB.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; NAS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; TAS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:0006359; P:regulation of transcription from RNA polymerase III promoter; TAS:UniProtKB.
343Q12899    539   TRI26_HUMAN Tripartite motif-containing prote...550.29     37     35     47
GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
344Q7YR34    539   TRI26_PANTR Tripartite motif-containing prote...550.29     37     35     47
GO:0008270; F:zinc ion binding; IEA:InterPro.
345Q6J6I8    1863   BRCA1_GORGO Breast cancer type 1 susceptibili...570.31     37.4     35     54GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.
346Q5SWK7    663   RN145_MOUSE RING finger protein 145 OS=Mus mu...590.31     37     32     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
347Q95153    1878   BRCA1_CANFA Breast cancer type 1 susceptibili...570.31     37.4     35     54GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.
348O54952    1817   BRCA1_RAT Breast cancer type 1 susceptibility...580.32     37.4     31     55GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IDA:RGD.
GO:0003684; F:damaged DNA binding; TAS:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007420; P:brain development; IEP:RGD.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0033993; P:response to lipid; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.
349Q5XHH7    595   SYVNB_XENLA E3 ubiquitin-protein ligase synov...480.32     37     38     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
350P48754    1812   BRCA1_MOUSE Breast cancer type 1 susceptibili...580.33     37     31     55GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.::GO:0005813; C:centrosome; TAS:UniProtKB.::GO:0000794; C:condensed nuclear chromosome; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0003684; F:damaged DNA binding; IDA:MGI.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051298; P:centrosome duplication; TAS:UniProtKB.::GO:0043009; P:chordate embryonic development; IMP:MGI.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IMP:MGI.::GO:0009048; P:dosage compensation by inactivation of X chromosome; IDA:MGI.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0035067; P:negative regulation of histone acetylation; IMP:BHF-UCL.::GO:0051572; P:negative regulation of histone H3-K4 methylation; IMP:BHF-UCL.::GO:0051573; P:negative regulation of histone H3-K9 methylation; IMP:BHF-UCL.::GO:0051571; P:positive regulation of histone H3-K4 methylation; IMP:BHF-UCL.::GO:2000617; P:positive regulation of histone H3-K9 acetylation; IMP:BHF-UCL.::GO:0051574; P:positive regulation of histone H3-K9 methylation; IMP:BHF-UCL.::GO:2000620; P:positive regulation of histone H4-K16 acetylation; IMP:BHF-UCL.::GO:0070512; P:positive regulation of histone H4-K20 methylation; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0044030; P:regulation of DNA methylation; IMP:BHF-UCL.::GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:BHF-UCL.
351Q5TM55    465   TRI15_MACMU Tripartite motif-containing prote...540.34     36.6     33     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
352A2XW69    884   BRE1A_ORYSI E3 ubiquitin-protein ligase BRE1-...440.35     37     32     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
353P15533    496   TR30A_MOUSE Tripartite motif-containing prote...820.35     36.6     28     49GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032715; P:negative regulation of interleukin-6 production; IMP:UniProtKB.::GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IMP:UniProtKB.::GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IMP:UniProtKB.::GO:0032720; P:negative regulation of tumor necrosis factor production; IMP:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
354Q9DCN7    395   RNFT1_MOUSE RING finger and transmembrane dom...480.38     36.6     33     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
355Q6CJM4    1114   RAD5_KLULA DNA repair protein RAD5 OS=1267 / ...580.39     37     31     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
356Q9SK92    381   ATL15_ARATH E3 ubiquitin-protein ligase ATL15...590.39     36.6     27     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033591; P:response to L-ascorbic acid; IEP:TAIR.::GO:0009416; P:response to light stimulus; IEP:TAIR.
357Q7XU27    884   BRE1A_ORYSJ E3 ubiquitin-protein ligase BRE1-...440.39     36.6     32     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
358Q9ERP3    366   TRI54_MOUSE Tripartite motif-containing prote...630.4     36.2     32     43GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005875; C:microtubule associated complex; IDA:MGI.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0008017; F:microtubule binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007026; P:negative regulation of microtubule depolymerization; IDA:MGI.
359Q54S31    374   PEX10_DICDI Peroxisome biogenesis factor 10 O...560.41     36.2     32     46GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro.
GO:0008270; F:zinc ion binding; ISS:dictyBase.
GO:0016558; P:protein import into peroxisome matrix; IEA:InterPro.
360Q9Y7K6    741   YGI4_SCHPO Uncharacterized RING finger protei...530.41     36.6     32     42GO:0005634; C:nucleus; IDA:PomBase.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006325; P:chromatin organization; ISS:PomBase.::GO:0006342; P:chromatin silencing; ISS:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:PomBase.
361Q2PFU6    360   RN146_MACFA E3 ubiquitin-protein ligase RNF14...480.41     36.2     31     44GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
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