Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL054W
Length:
406
Number of sequences:
5887
Description:
YOL054W PSH1 SGDID:S000005415, Chr XV from 228614-229834, Genome Release 64-1-1, Verified ORF, "E3 ubiquitin ligase that mediates poyubiquitination and degradation of centromere-binding protein Cse4p and prevents Cse4p from mislocalizing to euchromatin; ubiquitylation of Cse4p may be antagonized by Scm3p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301P0CQ67    1198   RAD5_CRYNB DNA repair protein RAD5 OS=(Filoba...450.12     38.5     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
302P0CQ66    1198   RAD5_CRYNJ DNA repair protein RAD5 OS=ATCC MY...450.12     38.5     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
303Q8C0E3    641   TRI47_MOUSE Tripartite motif-containing prote...500.12     38.1     30     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
304Q86TM6    617   SYVN1_HUMAN E3 ubiquitin-protein ligase synov...550.13     38.1     36     51GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:HPA.
GO:0016881; F:acid-amino acid ligase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.
305Q1XH17    477   TRI72_MOUSE Tripartite motif-containing prote...700.13     38.1     34     49GO:0030659; C:cytoplasmic vesicle membrane; IDA:UniProtKB.::GO:0042383; C:sarcolemma; IDA:UniProtKB.
GO:0001786; F:phosphatidylserine binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006887; P:exocytosis; TAS:UniProtKB.::GO:0006900; P:membrane budding; TAS:UniProtKB.::GO:0007517; P:muscle organ development; IMP:UniProtKB.::GO:0003012; P:muscle system process; IMP:UniProtKB.::GO:0001778; P:plasma membrane repair; IMP:UniProtKB.::GO:0051260; P:protein homooligomerization; IPI:UniProtKB.
306Q75JQ3    423   PEX2_DICDI Peroxisome biogenesis factor 2 OS=...500.14     37.7     36     52GO:0005779; C:integral to peroxisomal membrane; IC:dictyBase.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007031; P:peroxisome organization; ISS:dictyBase.
307Q09463    235   RNF5_CAEEL RING finger protein 5 OS=Caenorhab...460.15     37.4     35     59GO:0030054; C:cell junction; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.::GO:0055120; C:striated muscle dense body; IDA:WormBase.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:WormBase.::GO:0055002; P:striated muscle cell development; IMP:WormBase.
308Q9M0R6    302   ATL35_ARATH Putative RING-H2 finger protein A...550.16     37.4     27     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
309Q9DBY1    612   SYVN1_MOUSE E3 ubiquitin-protein ligase synov...550.16     37.7     36     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006916; P:anti-apoptosis; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.
310Q32L60    407   TRI13_BOVIN E3 ubiquitin-protein ligase TRIM1...770.17     37.7     34     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
311Q6NRG0    532   RNF8B_XENLA E3 ubiquitin-protein ligase RNF8-...500.17     37.7     28     52GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:InterPro.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
312Q9BWF2    469   TRAIP_HUMAN TRAF-interacting protein OS=Homo ...520.17     37.7     35     50GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.
313Q6NRL6    605   SYVNA_XENLA E3 ubiquitin-protein ligase synov...480.17     37.7     38     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
314Q7ZW16    318   RNF41_DANRE E3 ubiquitin-protein ligase NRDP1...520.17     37.4     37     56
GO:0031386; F:protein tag; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0030318; P:melanocyte differentiation; IMP:ZFIN.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
315Q8BFW4    522   TRI65_MOUSE Tripartite motif-containing prote...460.17     37.7     37     57
GO:0008270; F:zinc ion binding; IEA:InterPro.
316Q75CC8    575   HRD1_ASHGO ERAD-associated E3 ubiquitin-prote...580.18     37.7     33     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
317P53769    259   CWC24_YEAST Pre-mRNA-splicing factor CWC24 OS...600.18     37     28     48GO:0005684; C:U2-type spliceosomal complex; IDA:SGD.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0034247; P:snoRNA splicing; IMP:SGD.
318Q8WV44    630   TRI41_HUMAN E3 ubiquitin-protein ligase TRIM4...300.19     37.7     47     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
319Q8BGE7    488   TRIM6_MOUSE Tripartite motif-containing prote...860.2     37.4     27     50GO:0005737; C:cytoplasm; IDA:MGI.
GO:0008270; F:zinc ion binding; IEA:InterPro.
320Q864U1    1849   BRCA1_BOVIN Breast cancer type 1 susceptibili...570.2     37.7     35     54GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.
321Q640S6    477   TRI72_XENTR Tripartite motif-containing prote...600.2     37.4     32     45GO:0030659; C:cytoplasmic vesicle membrane; ISS:UniProtKB.::GO:0042383; C:sarcolemma; ISS:UniProtKB.
GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; ISS:UniProtKB.::GO:0003012; P:muscle system process; ISS:UniProtKB.::GO:0001778; P:plasma membrane repair; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
322P39429    501   TRAF2_MOUSE TNF receptor-associated factor 2 ...590.21     37.4     31     46GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL.
GO:0005174; F:CD40 receptor binding; IPI:BHF-UCL.::GO:0046625; F:sphingolipid binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006916; P:anti-apoptosis; NAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043623; P:cellular protein complex assembly; IDA:BHF-UCL.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0030163; P:protein catabolic process; IMP:MGI.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0051023; P:regulation of immunoglobulin secretion; IMP:MGI.::GO:0033209; P:tumor necrosis factor-mediated signaling pathway; ISS:UniProtKB.
323Q9BVG3    475   TRI62_HUMAN Tripartite motif-containing prote...760.21     37.4     32     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
324Q8VIG6    470   TRAIP_MOUSE TRAF-interacting protein OS=Mus m...520.22     37.4     35     50GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.::GO:0005057; F:receptor signaling protein activity; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
325O74349    1610   LTN1_SCHPO E3 ubiquitin-protein ligase lister...550.22     37.7     33     44GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006342; P:chromatin silencing; NAS:PomBase.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; ISS:PomBase.
326Q96MT1    663   RN145_HUMAN RING finger protein 145 OS=Homo s...580.22     37.4     31     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
327Q9C029    511   TRIM7_HUMAN Tripartite motif-containing prote...540.23     37.4     33     46GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
328Q4WDD7    725   BRE1_ASPFU E3 ubiquitin-protein ligase bre1 O...510.23     37.4     29     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
329Q9FIY7    1277   SM3L3_ARATH Putative SWI/SNF-related matrix-a...460.23     37.7     37     52GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
330Q13114    568   TRAF3_HUMAN TNF receptor-associated factor 3 ...570.23     37.4     28     47GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; TAS:ProtInc.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0050688; P:regulation of defense response to virus; ISS:UniProtKB.::GO:0032648; P:regulation of interferon-beta production; ISS:UniProtKB.::GO:0030162; P:regulation of proteolysis; IMP:UniProtKB.::GO:0002224; P:toll-like receptor signaling pathway; ISS:UniProtKB.::GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IMP:UniProtKB.
331Q80V85    475   TRI62_MOUSE Tripartite motif-containing prote...690.24     37.4     33     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
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