UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YOL051W

Length:

1081

Number of sequences:

5887

Description:

YOL051W GAL11 SGDID:S000005411, Chr XV from 234940-238185, Genome Release 64-1-1, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors; forms part of the tail domain of mediator"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P19659	1081	MED15_YEAST Mediator of RNA polymerase II tra...	1081	0	2166	100	100	GO:0070847; C:core mediator complex; IDA:SGD.::GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001102; F:RNA polymerase II activating transcription factor binding; IDA:SGD.::GO:0001128; F:RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly; IDA:SGD.::GO:0001135; F:RNA polymerase II transcription factor recruiting transcription factor activity; IMP:SGD.::GO:0001088; F:TFIIE-class binding transcription factor activity; IDA:SGD.::GO:0001095; F:TFIIE-class transcription factor binding; IDA:SGD.::GO:0001097; F:TFIIH-class transcription factor binding; IDA:SGD.
									GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.
2	P32257	1034	MED15_KLULA Mediator of RNA polymerase II tra...	599	5e-85	302	35	54	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
3	Q6FRS9	1095	MED15_CANGA Mediator of RNA polymerase II tra...	136	2e-47	188	62	85	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
4	Q75BI6	1323	MED15_ASHGO Mediator of RNA polymerase II tra...	120	2e-26	121	42	74	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
5	Q9Y808	1063	YN91_SCHPO Uncharacterized protein C146.01 OS...	89	0.042	41.6	25	48	GO:0016592; C:mediator complex; ISS:PomBase.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; ISS:PomBase.
6	Q75AA0	1203	PAN1_ASHGO Actin cytoskeleton-regulatory comp...	42	8.8	34.3	55	76	GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
7	Q9JI55	4473	PLEC_CRIGR Plectin OS=Cricetulus griseus (Chi...	209	2.1	36.2	20	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IDA:UniProtKB.
									GO:0003779; F:actin binding; IEA:UniProtKB-KW.
8	P30427	4687	PLEC_RAT Plectin OS=Rattus norvegicus (Rat). ...	119	0.25	39.3	21	49	GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030056; C:hemidesmosome; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0042383; C:sarcolemma; IDA:RGD.
									GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; IDA:RGD.::GO:0005200; F:structural constituent of cytoskeleton; IMP:RGD.
									GO:0030855; P:epithelial cell differentiation; IEP:RGD.::GO:0007565; P:female pregnancy; IEP:RGD.::GO:0031581; P:hemidesmosome assembly; ISS:UniProtKB.::GO:0007584; P:response to nutrient; IDA:RGD.
9	P12080	1396	ITA2_DROME Integrin alpha-PS2 OS=Drosophila m...	89	0.36	38.5	31	44	GO:0043292; C:contractile fiber; IDA:FlyBase.::GO:0008305; C:integrin complex; NAS:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.
									GO:0050839; F:cell adhesion molecule binding; IDA:FlyBase.::GO:0004872; F:receptor activity; IDA:FlyBase.
									GO:0007475; P:apposition of dorsal and ventral imaginal disc-derived wing surfaces; NAS:FlyBase.::GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0007414; P:axonal defasciculation; IMP:FlyBase.::GO:0007427; P:epithelial cell migration, open tracheal system; TAS:FlyBase.::GO:0007157; P:heterophilic cell-cell adhesion; TAS:FlyBase.::GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.::GO:0035160; P:maintenance of epithelial integrity, open tracheal system; IGI:FlyBase.::GO:0045185; P:maintenance of protein location; IMP:FlyBase.::GO:0007494; P:midgut development; TAS:FlyBase.::GO:0016203; P:muscle attachment; IMP:FlyBase.::GO:0030239; P:myofibril assembly; IMP:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IGI:FlyBase.::GO:0007608; P:sensory perception of smell; IGI:FlyBase.::GO:0007426; P:tracheal outgrowth, open tracheal system; TAS:FlyBase.
10	Q9QXS1	4691	PLEC_MOUSE Plectin OS=Mus musculus (Mouse). G...	95	0.41	38.5	24	54	GO:0043292; C:contractile fiber; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030056; C:hemidesmosome; ISS:UniProtKB.::GO:0005626; C:insoluble fraction; IDA:MGI.::GO:0042383; C:sarcolemma; ISS:UniProtKB.
									GO:0003779; F:actin binding; IEA:UniProtKB-KW.
									GO:0031581; P:hemidesmosome assembly; ISS:UniProtKB.
11	Q12830	3046	BPTF_HUMAN Nucleosome-remodeling factor subun...	84	0.84	37.7	30	50	GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0016589; C:NURF complex; IDA:UniProtKB.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0043565; F:sequence-specific DNA binding; IDA:HGNC.::GO:0008134; F:transcription factor binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0007420; P:brain development; IMP:HGNC.::GO:0006338; P:chromatin remodeling; IDA:HGNC.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:HGNC.::GO:0006351; P:transcription, DNA-dependent; IMP:HGNC.
12	C5DT56	362	BBP1_ZYGRC Spindle pole component BBP1 OS=NCY...	127	1.7	36.2	23	52	GO:0005634; C:nucleus; IEA:UniProtKB-KW.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
13	B7VJH7	896	IF2_VIBSL Translation initiation factor IF-2 ...	93	4.3	35	31	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
14	Q5R7U0	838	GASP2_PONAB G-protein coupled receptor-associ...	117	6.2	34.7	24	48
15	Q8KFT1	914	IF2_CHLTE Translation initiation factor IF-2 ...	81	7.7	34.3	27	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
16	Q15149	4684	PLEC_HUMAN Plectin OS=Homo sapiens (Human). G...	127	8.1	34.3	20	47	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0030056; C:hemidesmosome; IDA:UniProtKB.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0042383; C:sarcolemma; IDA:UniProtKB.
									GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
									GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0031581; P:hemidesmosome assembly; IDA:UniProtKB.
17	P11829	137	ACP1_ARATH Acyl carrier protein 1, chloroplas...	67	8.7	32.3	28	51	GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.
									GO:0000036; F:acyl carrier activity; IDA:TAIR.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; TAS:TAIR.

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