Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL045W
Length:
1101
Number of sequences:
5887
Description:
YOL045W PSK2 SGDID:S000005405, Chr XV from 243497-246802, Genome Release 64-1-1, Verified ORF, "One of two (see also PSK1) PAS domain containing S/T protein kinases; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p "
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q86V86    326   PIM3_HUMAN Serine/threonine-protein kinase pi...2652e-33     137     35     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0061179; P:negative regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; IMP:UniProtKB.
32Q9BXA7    367   TSSK1_HUMAN Testis-specific serine/threonine-...2747e-33     136     35     53GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0019861; C:flagellum; ISS:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007286; P:spermatid development; ISS:UniProtKB.
33O60285    661   NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS...2999e-33     139     31     51GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030155; P:regulation of cell adhesion; IDA:UniProtKB.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:2000772; P:regulation of cellular senescence; IDA:UniProtKB.::GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; IDA:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.
34O70444    326   PIM3_RAT Serine/threonine-protein kinase pim-...2659e-33     135     35     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016572; P:histone phosphorylation; IDA:RGD.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0061179; P:negative regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0007346; P:regulation of mitotic cell cycle; ISS:UniProtKB.
35P58750    326   PIM3_MOUSE Serine/threonine-protein kinase pi...2659e-33     135     35     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0061179; P:negative regulation of insulin secretion involved in cellular response to glucose stimulus; IMP:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; ISS:UniProtKB.
36Q8C0V7    499   SMKW_MOUSE Sperm motility kinase W OS=Mus mus...2671e-32     137     34     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.
37Q641K5    658   NUAK1_MOUSE NUAK family SNF1-like kinase 1 OS...2681e-32     139     33     52GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030155; P:regulation of cell adhesion; ISS:UniProtKB.::GO:2000772; P:regulation of cellular senescence; ISS:UniProtKB.::GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.
38Q96PF2    358   TSSK2_HUMAN Testis-specific serine/threonine-...2698e-32     133     34     55GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0007286; P:spermatid development; ISS:UniProtKB.
39Q8C0X8    640   SMKX_MOUSE Sperm motility kinase X OS=Mus mus...2679e-32     136     34     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
40Q8C0N0    497   SMKZ_MOUSE Sperm motility kinase Z OS=Mus mus...2737e-31     132     30     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
41P06782    633   SNF1_YEAST Carbon catabolite-derepressing pro...2877e-31     133     31     51GO:0031588; C:AMP-activated protein kinase complex; IDA:SGD.::GO:0000324; C:fungal-type vacuole; IPI:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005641; C:nuclear envelope lumen; IDA:SGD.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0004679; F:AMP-activated protein kinase activity; IDA:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0042710; P:biofilm formation; IMP:SGD.::GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IMP:SGD.::GO:0006995; P:cellular response to nitrogen starvation; IDA:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0017148; P:negative regulation of translation; IMP:SGD.::GO:0045722; P:positive regulation of gluconeogenesis; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD.::GO:0007165; P:signal transduction; TAS:SGD.
42Q9H0K1    926   SIK2_HUMAN Serine/threonine-protein kinase SI...2681e-30     134     34     52GO:0005794; C:Golgi apparatus; IDA:HPA.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; ISS:UniProtKB.
43Q8CFH6    931   SIK2_MOUSE Serine/threonine-protein kinase SI...2684e-30     132     32     52GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0008286; P:insulin receptor signaling pathway; IDA:MGI.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; IDA:UniProtKB.
44Q00372    612   SNF1_CANGA Carbon catabolite-derepressing pro...2905e-30     130     31     52GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
45Q54DF2    1060   MRKA_DICDI Probable serine/threonine-protein ...2845e-30     132     29     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
46O08678    793   MARK1_RAT Serine/threonine-protein kinase MAR...2715e-30     132     31     54GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0015630; C:microtubule cytoskeleton; NAS:RGD.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0070300; F:phosphatidic acid binding; ISS:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.::GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0000226; P:microtubule cytoskeleton organization; IDA:RGD.::GO:0001764; P:neuron migration; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
47Q54TA3    773   MRKC_DICDI Probable serine/threonine-protein ...2836e-30     131     31     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
48Q8VHJ5    795   MARK1_MOUSE Serine/threonine-protein kinase M...2697e-30     131     31     54GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0070300; F:phosphatidic acid binding; ISS:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.::GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
49Q8IY84    436   NIM1_HUMAN Serine/threonine-protein kinase NI...2721e-29     127     33     52
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
50Q9P0L2    795   MARK1_HUMAN Serine/threonine-protein kinase M...2691e-29     130     31     54GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0015630; C:microtubule cytoskeleton; TAS:ProtInc.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0070300; F:phosphatidic acid binding; IDA:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.::GO:0001786; F:phosphatidylserine binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
51Q5REX1    925   SIK2_PONAB Serine/threonine-protein kinase SI...2682e-29     130     33     52GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; ISS:UniProtKB.
52Q9QYZ5    504   SMK3_MOUSE Sperm motility kinase 3 OS=Mus mus...2693e-29     127     30     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
53O64629    288   AUR3_ARATH Serine/threonine-protein kinase Au...2833e-29     124     29     52GO:0000775; C:chromosome, centromeric region; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035175; F:histone kinase activity (H3-S10 specific); IDA:TAIR.::GO:0044022; F:histone kinase activity (H3-S28 specific); IDA:TAIR.
54Q61RA2    493   CHK1_CAEBR Serine/threonine-protein kinase ch...2734e-29     126     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.
55Q9H093    628   NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS...2665e-29     127     31     53
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
56Q5R7G9    628   NUAK2_PONAB NUAK family SNF1-like kinase 2 OS...2665e-29     127     31     53
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
57A0AUV4    508   SMKY_MOUSE Sperm motility kinase Y OS=Mus mus...2715e-29     126     30     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
58A1A5Q6    654   SMK_RAT Sperm motility kinase OS=Rattus norve...2695e-29     127     32     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
59O61661    512   CHK1_DROME Serine/threonine-protein kinase gr...3035e-29     126     28     47GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.
GO:0007050; P:cell cycle arrest; IMP:FlyBase.::GO:0007349; P:cellularization; TAS:FlyBase.::GO:0051299; P:centrosome separation; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; TAS:FlyBase.::GO:0016321; P:female meiosis chromosome segregation; IMP:FlyBase.::GO:0007444; P:imaginal disc development; TAS:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IMP:FlyBase.::GO:0030162; P:regulation of proteolysis; TAS:FlyBase.::GO:0007348; P:regulation of syncytial blastoderm mitotic cell cycle; IMP:UniProtKB.::GO:0009314; P:response to radiation; TAS:FlyBase.::GO:0051225; P:spindle assembly; IMP:FlyBase.
60Q69Q47    453   CIPKO_ORYSJ CBL-interacting protein kinase 24...2816e-29     125     32     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
61Q8AYC9    476   CHK1_CHICK Serine/threonine-protein kinase Ch...2736e-29     125     30     49GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035402; F:histone kinase activity (H3-T11 specific); ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0048096; P:chromatin-mediated maintenance of transcription; ISS:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; ISS:UniProtKB.::GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0045839; P:negative regulation of mitosis; ISS:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:2000615; P:regulation of histone H3-K9 acetylation; ISS:UniProtKB.::GO:0046602; P:regulation of mitotic centrosome separation; ISS:UniProtKB.::GO:0010767; P:regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; ISS:UniProtKB.
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