UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YOL043C

Length:

380

Number of sequences:

5887

Description:

YOL043C NTG2 SGDID:S000005403, Chr XV from 249534-248392, Genome Release 64-1-1, reverse complement, Verified ORF, "DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision repair, localizes to the nucleus; sumoylated"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	Q08214	380	NTG2_YEAST DNA base excision repair N-glycosy...	380	0	787	100	100	GO:0005634; C:nucleus; IDA:SGD.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000703; F:oxidized pyrimidine base lesion DNA N-glycosylase activity; IDA:SGD.
									GO:0006285; P:base-excision repair, AP site formation; IDA:SGD.
2	P31378	399	NTG1_YEAST Mitochondrial DNA base excision re...	285	2e-98	305	51	67	GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0008534; F:oxidized purine base lesion DNA N-glycosylase activity; IDA:SGD.::GO:0000703; F:oxidized pyrimidine base lesion DNA N-glycosylase activity; IDA:SGD.
									GO:0006285; P:base-excision repair, AP site formation; IDA:SGD.::GO:0034599; P:cellular response to oxidative stress; IMP:SGD.::GO:0090297; P:positive regulation of mitochondrial DNA replication; IMP:SGD.
3	Q09907	355	NTH1_SCHPO Endonuclease III homolog OS=Schizo...	241	8e-60	203	43	59	GO:0005759; C:mitochondrial matrix; ISS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0034042; F:5-formyluracil DNA N-glycosylase activity; IDA:PomBase.::GO:0034043; F:5-hydroxymethyluracil DNA N-glycosylase activity; IDA:PomBase.::GO:0034039; F:8-oxo-7,8-dihydroguanine DNA N-glycosylase activity; IDA:PomBase.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006285; P:base-excision repair, AP site formation; IDA:PomBase.
4	Q2KID2	305	NTHL1_BOVIN Endonuclease III-like protein 1 O...	240	7e-49	173	38	54	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
5	O35980	300	NTHL1_MOUSE Endonuclease III-like protein 1 O...	240	9e-49	172	38	55	GO:0005739; C:mitochondrion; IDA:UniProtKB.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0019104; F:DNA N-glycosylase activity; IDA:UniProtKB.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:UniProtKB.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.::GO:0006296; P:nucleotide-excision repair, DNA incision, 5'-to lesion; IDA:UniProtKB.
6	P78549	312	NTHL1_HUMAN Endonuclease III-like protein 1 O...	230	4e-46	166	38	55	GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0019104; F:DNA N-glycosylase activity; IDA:UniProtKB.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:UniProtKB.::GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.::GO:0004519; F:endonuclease activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0045008; P:depyrimidination; TAS:Reactome.::GO:0006296; P:nucleotide-excision repair, DNA incision, 5'-to lesion; IDA:UniProtKB.
7	P54137	298	NTH1_CAEEL Probable endonuclease III homolog ...	238	1e-45	164	38	54	GO:0005634; C:nucleus; ISS:WormBase.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0034042; F:5-formyluracil DNA N-glycosylase activity; IDA:WormBase.::GO:0034043; F:5-hydroxymethyluracil DNA N-glycosylase activity; IDA:WormBase.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0045008; P:depyrimidination; IDA:WormBase.
8	Q8SRB8	238	NTH1_ENCCU Endonuclease III homolog OS=Enceph...	241	2e-33	129	32	51
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
9	Q9WYK0	213	END3_THEMA Endonuclease III OS=Thermotoga mar...	196	3e-23	100	32	49	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
10	Q58030	344	Y613_METJA Putative endonuclease MJ0613 OS=JC...	207	2e-22	100	37	54	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
11	P73715	219	END3_SYNY3 Endonuclease III OS=Synechocystis ...	190	6e-19	88.2	28	48	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
12	Q9CB92	245	END3_MYCLE Endonuclease III OS=Mycobacterium ...	190	8e-19	88.2	31	48	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
13	P63540	245	END3_MYCTU Endonuclease III OS=Mycobacterium ...	192	3e-17	84	31	47	GO:0005618; C:cell wall; IDA:MTBBASE.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0019104; F:DNA N-glycosylase activity; IDA:MTBBASE.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0003690; F:double-stranded DNA binding; IDA:MTBBASE.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
14	P63541	245	END3_MYCBO Endonuclease III OS=Mycobacterium ...	192	3e-17	84	31	47	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
15	P46303	279	UVEN_MICLC Ultraviolet N-glycosylase/AP lyase...	181	1e-16	82.8	29	46	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
16	Q4UK93	213	END3_RICFE Endonuclease III OS=Rickettsia fel...	201	0.00000000000004	74.3	29	45	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
17	P44319	211	END3_HAEIN Endonuclease III OS=Haemophilus in...	190	0.0000000000001	73.2	26	47	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
18	Q89AW4	215	END3_BUCBP Endonuclease III OS=Buchnera aphid...	201	0.0000000000001	73.2	30	44	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
19	P0AB83	211	END3_ECOLI Endonuclease III OS=Escherichia co...	187	0.0000000000001	72.8	25	44	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006284; P:base-excision repair; IEA:InterPro.
20	P0AB84	211	END3_ECOL6 Endonuclease III OS=Escherichia co...	187	0.0000000000001	72.8	25	44	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
21	O83754	211	END3_TREPA Endonuclease III OS=Treponema pall...	191	0.0000000000005	71.2	27	43	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
22	Q92GH4	210	END3_RICCN Endonuclease III OS=Rickettsia con...	193	0.000000000004	68.6	27	46	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
23	P57219	210	END3_BUCAI Endonuclease III OS=(Acyrthosiphon...	187	0.00000000002	66.2	28	47	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
24	Q68W04	212	END3_RICTY Endonuclease III OS=Rickettsia typ...	187	0.00000000008	64.7	28	44	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
25	P39788	219	END3_BACSU Probable endonuclease III OS=Bacil...	191	0.0000000002	63.9	25	45	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
26	O05956	212	END3_RICPR Endonuclease III OS=Rickettsia pro...	192	0.0000000006	62	27	45	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
27	Q8KA16	209	END3_BUCAP Endonuclease III OS=Buchnera aphid...	187	0.000002	52	24	43	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
28	Q89A45	351	MUTY_BUCBP A/G-specific adenine glycosylase O...	152	0.000005	51.6	26	45	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0019104; F:DNA N-glycosylase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
29	P29588	221	GTMR_METTF G/T mismatches repair enzyme OS=Me...	149	0.001	43.5	21	45
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
30	Q58829	220	Y1434_METJA Putative endonuclease MJ1434 OS=J...	204	0.004	42	24	41
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.
31	O31584	369	YFHQ_BACSU Probable A/G-specific adenine glyc...	157	0.018	40.4	25	41	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0019104; F:DNA N-glycosylase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006284; P:base-excision repair; IEA:InterPro.

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