Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL027C
Length:
573
Number of sequences:
5887
Description:
YOL027C MDM38 SGDID:S000005387, Chr XV from 273724-272003, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial protein, forms a complex with Mba1p to facilitate recruitment of mRNA-specific translational activators to ribosomes; roles in protein export and K+/H+ exchange; human ortholog Letm1 implicated in Wolf-Hirschhorn syndrome"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q08179    573   MDM38_YEAST Mitochondrial distribution and mo...5730     1168     100     100GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IDA:SGD.
GO:0043022; F:ribosome binding; IDA:SGD.
GO:0030007; P:cellular potassium ion homeostasis; IMP:SGD.::GO:0097033; P:mitochondrial respiratory chain complex III biogenesis; IMP:SGD.::GO:0097034; P:mitochondrial respiratory chain complex IV biogenesis; IMP:SGD.::GO:0070131; P:positive regulation of mitochondrial translation; IGI:SGD.::GO:0006813; P:potassium ion transport; IMP:SGD.::GO:0051204; P:protein insertion into mitochondrial membrane; IMP:SGD.
2Q06493    454   YLH47_YEAST LETM1 domain-containing protein Y...3512e-82     271     42     62GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IDA:SGD.
GO:0051204; P:protein insertion into mitochondrial membrane; IMP:SGD.
3O13920    485   YDWH_SCHPO Uncharacterized protein C23C11.17 ...3827e-73     247     41     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; ISS:PomBase.
GO:0030007; P:cellular potassium ion homeostasis; ISS:PomBase.::GO:0071805; P:potassium ion transmembrane transport; ISS:PomBase.::GO:0051204; P:protein insertion into mitochondrial membrane; ISS:PomBase.
4Q5ZK33    752   LETM1_CHICK LETM1 and EF-hand domain-containi...5476e-65     231     33     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.
5Q0VCA3    732   LETM1_BOVIN LETM1 and EF-hand domain-containi...4524e-64     229     35     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.
6P91927    1013   A60DA_DROME LETM1 and EF-hand domain-containi...2907e-64     230     40     63GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IDA:FlyBase.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005432; F:calcium:sodium antiporter activity; IDA:FlyBase.
GO:0071456; P:cellular response to hypoxia; IMP:FlyBase.::GO:0006851; P:mitochondrial calcium ion transport; IMP:FlyBase.
7Q0VA06    760   LETM1_XENTR LETM1 and EF-hand domain-containi...2698e-62     223     41     64GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.
8Q1LY46    757   LETM1_DANRE LETM1 and EF-hand domain-containi...4344e-60     218     34     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.
9O95202    739   LETM1_HUMAN LETM1 and EF-hand domain-containi...3572e-53     198     37     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB.
GO:0005509; F:calcium ion binding; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0042407; P:cristae formation; IMP:UniProtKB.
10Q5XIN6    739   LETM1_RAT LETM1 and EF-hand domain-containing...4115e-53     197     35     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.
11Q9Z2I0    738   LETM1_MOUSE LETM1 and EF-hand domain-containi...2757e-53     196     40     63GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
GO:0005509; F:calcium ion binding; IEA:InterPro.
12Q7TNU7    480   LETM2_MOUSE LETM1 domain-containing protein L...2786e-47     176     37     61GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
13Q2VYF4    491   LETM2_HUMAN LETM1 domain-containing protein L...3389e-46     173     36     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
14Q5PQQ5    459   LETM2_RAT LETM1 domain-containing protein LET...3167e-44     167     35     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
15Q28DA8    444   LETM2_XENTR LETM1 domain-containing protein L...2741e-43     166     36     62GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
16Q28EM8    351   LTMD1_XENTR LETM1 domain-containing protein 1...2240.00000009     58.2     25     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
17A3KN46    360   LTMD1_BOVIN LETM1 domain-containing protein 1...2300.0000005     55.8     25     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
18Q6P1Q0    360   LTMD1_HUMAN LETM1 domain-containing protein 1...2300.00003     50.1     24     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
19Q924L1    360   LTMD1_MOUSE LETM1 domain-containing protein 1...2410.15     38.1     21     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
20P03949    1224   ABL1_CAEEL Tyrosine-protein kinase abl-1 OS=C...830.54     37     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0019901; F:protein kinase binding; IPI:WormBase.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0000077; P:DNA damage checkpoint; IGI:WormBase.::GO:0043066; P:negative regulation of apoptotic process; IMP:WormBase.::GO:0030336; P:negative regulation of cell migration; IGI:WormBase.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IMP:WormBase.::GO:0060101; P:negative regulation of phagocytosis, engulfment; IGI:WormBase.::GO:0010212; P:response to ionizing radiation; IMP:WormBase.::GO:0007283; P:spermatogenesis; IMP:WormBase.
21Q3ANE6    502   SYK_SYNSC Lysine--tRNA ligase OS=Synechococcu...1451.3     35.4     23     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004824; F:lysine-tRNA ligase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006430; P:lysyl-tRNA aminoacylation; IEA:InterPro.
22Q9D1J3    210   SARNP_MOUSE SAP domain-containing ribonucleop...302.1     34.3     43     77GO:0005634; C:nucleus; IDA:MGI.
GO:0008022; F:protein C-terminus binding; IPI:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:MGI.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IMP:MGI.::GO:0050733; F:RS domain binding; IPI:MGI.
GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
23Q12019    4910   MDN1_YEAST Midasin OS=Saccharomyces cerevisia...1434.3     34.3     24     45GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005654; C:nucleoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0006461; P:protein complex assembly; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0000027; P:ribosomal large subunit assembly; IMP:SGD.::GO:0006364; P:rRNA processing; IMP:SGD.
24P13009    1227   METH_ECOLI Methionine synthase OS=Escherichia...936.8     33.5     28     49GO:0005737; C:cytoplasm; IDA:EcoliWiki.
GO:0031419; F:cobalamin binding; IDA:EcoCyc.::GO:0008898; F:homocysteine S-methyltransferase activity; IDA:EcoCyc.::GO:0008705; F:methionine synthase activity; IDA:EcoCyc.::GO:0008270; F:zinc ion binding; IMP:EcoCyc.
GO:0042558; P:pteridine-containing compound metabolic process; IEA:InterPro.
25Q498U4    210   SARNP_RAT SAP domain-containing ribonucleopro...297.4     32.3     41     76GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26Q8IIG1    2545   YK213_PLAF7 Uncharacterized protein PF11_0213...978     33.1     27     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
records
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