rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q08162 | 1001 | RRP44_YEAST Exosome complex exonuclease DIS3 ... | 1001 | 0 | 2070 | 100 | 100 | GO:0000177; C:cytoplasmic exosome (RNase complex); IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0000176; C:nuclear exosome (RNase complex); IDA:SGD.::GO:0005730; C:nucleolus; IDA:SGD. | | | | | | | | | | GO:0000175; F:3'-5'-exoribonuclease activity; IDA:SGD.::GO:0004521; F:endoribonuclease activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0000049; F:tRNA binding; IDA:SGD. | | | | | | | | | | GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0070651; P:nonfunctional rRNA decay; IMP:SGD.::GO:0071028; P:nuclear mRNA surveillance; IMP:SGD.::GO:0071039; P:nuclear polyadenylation-dependent CUT catabolic process; IMP:SGD.::GO:0071042; P:nuclear polyadenylation-dependent mRNA catabolic process; IC:SGD.::GO:0071035; P:nuclear polyadenylation-dependent rRNA catabolic process; IMP:SGD.::GO:0071038; P:nuclear polyadenylation-dependent tRNA catabolic process; IDA:SGD.::GO:0070478; P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; IC:SGD.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; IC:SGD.::GO:0071051; P:polyadenylation-dependent snoRNA 3'-end processing; IC:SGD. | 2 | P37202 | 970 | DIS3_SCHPO Exosome complex exonuclease dis3 O... | 985 | 0 | 1014 | 52 | 70 | GO:0000177; C:cytoplasmic exosome (RNase complex); ISS:PomBase.::GO:0005739; C:mitochondrion; ISS:PomBase.::GO:0000176; C:nuclear exosome (RNase complex); ISS:PomBase. | | | | | | | | | | GO:0000175; F:3'-5'-exoribonuclease activity; ISS:PomBase.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0008536; F:Ran GTPase binding; IPI:PomBase.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:PomBase.::GO:0000465; P:exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0070651; P:nonfunctional rRNA decay; ISS:PomBase.::GO:0071042; P:nuclear polyadenylation-dependent mRNA catabolic process; ISS:PomBase.::GO:0071035; P:nuclear polyadenylation-dependent rRNA catabolic process; ISS:PomBase.::GO:0071038; P:nuclear polyadenylation-dependent tRNA catabolic process; ISS:PomBase.::GO:0070478; P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; ISS:PomBase.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; ISS:PomBase.::GO:0032853; P:positive regulation of Ran GTPase activity; IMP:PomBase.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0007051; P:spindle organization; IMP:PomBase. | 3 | Q9CSH3 | 958 | RRP44_MOUSE Exosome complex exonuclease RRP44... | 971 | 0 | 763 | 43 | 62 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000176; C:nuclear exosome (RNase complex); ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0000175; F:3'-5'-exoribonuclease activity; ISS:UniProtKB.::GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006364; P:rRNA processing; IEA:UniProtKB-KW. | 4 | Q9Y2L1 | 958 | RRP44_HUMAN Exosome complex exonuclease RRP44... | 973 | 0 | 751 | 43 | 62 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0000176; C:nuclear exosome (RNase complex); IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0000175; F:3'-5'-exoribonuclease activity; IMP:UniProtKB.::GO:0004519; F:endonuclease activity; IMP:UniProtKB.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071034; P:CUT catabolic process; IMP:UniProtKB.::GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.::GO:0016075; P:rRNA catabolic process; IMP:UniProtKB.::GO:0006364; P:rRNA processing; TAS:UniProtKB. | 5 | Q17632 | 961 | RRP44_CAEEL Probable exosome complex exonucle... | 941 | 0 | 647 | 39 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0004540; F:ribonuclease activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW. | 6 | Q0P4R5 | 1039 | DI3L1_XENTR DIS3-like exonuclease 1 OS=Xenopu... | 966 | 2e-152 | 486 | 34 | 52 | GO:0000177; C:cytoplasmic exosome (RNase complex); ISS:UniProtKB. | | | | | | | | | | GO:0000175; F:3'-5'-exoribonuclease activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | | 7 | Q6GN11 | 1040 | DI3L1_XENLA DIS3-like exonuclease 1 OS=Xenopu... | 1021 | 1e-149 | 478 | 33 | 49 | GO:0000177; C:cytoplasmic exosome (RNase complex); ISS:UniProtKB. | | | | | | | | | | GO:0000175; F:3'-5'-exoribonuclease activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | | 8 | Q5U2P0 | 1054 | DI3L1_RAT DIS3-like exonuclease 1 OS=Rattus n... | 970 | 1e-149 | 478 | 35 | 51 | GO:0000177; C:cytoplasmic exosome (RNase complex); ISS:UniProtKB. | | | | | | | | | | GO:0000175; F:3'-5'-exoribonuclease activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | | 9 | Q8C0S1 | 1053 | DI3L1_MOUSE DIS3-like exonuclease 1 OS=Mus mu... | 974 | 2e-148 | 475 | 35 | 50 | GO:0000177; C:cytoplasmic exosome (RNase complex); ISS:UniProtKB. | | | | | | | | | | GO:0000175; F:3'-5'-exoribonuclease activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | | 10 | A0JN80 | 1053 | DI3L1_BOVIN DIS3-like exonuclease 1 OS=Bos ta... | 971 | 7e-147 | 471 | 34 | 51 | GO:0000177; C:cytoplasmic exosome (RNase complex); ISS:UniProtKB. | | | | | | | | | | GO:0000175; F:3'-5'-exoribonuclease activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | | 11 | Q5R5N8 | 1054 | DI3L1_PONAB DIS3-like exonuclease 1 OS=Pongo ... | 1016 | 5e-143 | 461 | 33 | 50 | GO:0000177; C:cytoplasmic exosome (RNase complex); ISS:UniProtKB. | | | | | | | | | | GO:0000175; F:3'-5'-exoribonuclease activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | | 12 | Q8TF46 | 1054 | DI3L1_HUMAN DIS3-like exonuclease 1 OS=Homo s... | 1015 | 5e-143 | 461 | 33 | 49 | GO:0005813; C:centrosome; IDA:HPA.::GO:0000177; C:cytoplasmic exosome (RNase complex); IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0000175; F:3'-5'-exoribonuclease activity; IDA:UniProtKB.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016075; P:rRNA catabolic process; IDA:UniProtKB. | 13 | A2RV18 | 1057 | DI3L1_DANRE DIS3-like exonuclease 1 OS=Danio ... | 1018 | 3e-142 | 459 | 33 | 51 | GO:0000177; C:cytoplasmic exosome (RNase complex); ISS:UniProtKB. | | | | | | | | | | GO:0000175; F:3'-5'-exoribonuclease activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | | 14 | Q8IYB7 | 885 | DI3L2_HUMAN DIS3-like exonuclease 2 OS=Homo s... | 820 | 5e-100 | 340 | 33 | 47 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0004540; F:ribonuclease activity; IDA:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051306; P:mitotic sister chromatid separation; IMP:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB. | 15 | Q8CI75 | 870 | DI3L2_MOUSE DIS3-like exonuclease 2 OS=Mus mu... | 776 | 6e-99 | 337 | 33 | 48 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0004540; F:ribonuclease activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051306; P:mitotic sister chromatid separation; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB. | 16 | Q0V9R3 | 834 | DI3L2_XENTR DIS3-like exonuclease 2 OS=Xenopu... | 755 | 6e-99 | 336 | 34 | 49 | | | | | | | | | | | GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0004540; F:ribonuclease activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | | 17 | O14040 | 927 | DIS3L_SCHPO Dis3-like exonuclease C2C4.07c OS... | 780 | 1e-89 | 313 | 32 | 49 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0004540; F:ribonuclease activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase. | 18 | Q09568 | 848 | YR86_CAEEL Uncharacterized ribonuclease F48E8... | 742 | 3e-87 | 304 | 31 | 49 | | | | | | | | | | | GO:0004540; F:ribonuclease activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro. | | | | | | | | | | | 19 | Q9WZI1 | 710 | RNR_THEMA Ribonuclease R OS=Thermotoga mariti... | 517 | 5e-55 | 207 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008859; F:exoribonuclease II activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 20 | O67834 | 705 | RNR_AQUAE Ribonuclease R OS=Aquifex aeolicus ... | 450 | 3e-49 | 190 | 31 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008859; F:exoribonuclease II activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 21 | Q9Z848 | 676 | RNR_CHLPN Ribonuclease R OS=Chlamydia pneumon... | 520 | 6e-49 | 189 | 30 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008859; F:exoribonuclease II activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 22 | O84402 | 694 | RNR_CHLTR Ribonuclease R OS=Chlamydia trachom... | 424 | 3e-47 | 184 | 32 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008859; F:exoribonuclease II activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 23 | O32231 | 779 | RNR_BACSU Ribonuclease R OS=Bacillus subtilis... | 445 | 5e-47 | 184 | 31 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008859; F:exoribonuclease II activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 24 | Q9PK00 | 692 | RNR_CHLMU Ribonuclease R OS=Chlamydia muridar... | 424 | 1e-45 | 179 | 32 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008859; F:exoribonuclease II activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 25 | Q9CH00 | 817 | RNR1_LACLA Ribonuclease R 1 OS=lactis). GN=rn... | 594 | 2e-44 | 177 | 27 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008859; F:exoribonuclease II activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 26 | Q98QL0 | 725 | RNR_MYCPU Ribonuclease R OS=Mycoplasma pulmon... | 482 | 2e-41 | 166 | 30 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008859; F:exoribonuclease II activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 27 | Q02146 | 665 | RNR2_LACLA Ribonuclease R 2 OS=lactis). GN=rn... | 505 | 4e-40 | 162 | 29 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008859; F:exoribonuclease II activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 28 | Q9PR88 | 721 | RNR_UREPA Ribonuclease R OS=Ureaplasma parvum... | 480 | 8e-40 | 161 | 29 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008859; F:exoribonuclease II activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 29 | P21499 | 813 | RNR_ECOLI Ribonuclease R OS=Escherichia coli ... | 564 | 5e-39 | 160 | 27 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000175; F:3'-5'-exoribonuclease activity; IDA:EcoCyc.::GO:0008859; F:exoribonuclease II activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016556; P:mRNA modification; IDA:EcoCyc.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0000154; P:rRNA modification; IDA:EcoCyc. | 30 | P30851 | 813 | RNR_SHIFL Ribonuclease R OS=Shigella flexneri... | 564 | 8e-39 | 159 | 27 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008859; F:exoribonuclease II activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 31 | Q9KNY1 | 821 | RNR_VIBCH Ribonuclease R OS=Vibrio cholerae s... | 526 | 1e-37 | 155 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008859; F:exoribonuclease II activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. |