Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL018C
Length:
397
Number of sequences:
5887
Description:
YOL018C TLG2 SGDID:S000005378, Chr XV from 292074-290881, Genome Release 64-1-1, reverse complement, Verified ORF, "Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds Vps45p, which prevents Tlg2p degradation and also facilitates t-SNARE complex formation; homologous to mammalian SNARE protein syntaxin 16 (Sx16)"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q08144    397   TLG2_YEAST T-SNARE affecting a late Golgi com...3970     815     100     100GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0031303; C:integral to endosome membrane; IDA:SGD.::GO:0005802; C:trans-Golgi network; IDA:SGD.
GO:0005484; F:SNAP receptor activity; IDA:SGD.
GO:0032258; P:CVT pathway; IMP:SGD.::GO:0006897; P:endocytosis; IMP:SGD.::GO:0006896; P:Golgi to vacuole transport; IGI:SGD.::GO:0006674; P:inositol phosphorylceramide metabolic process; IMP:SGD.::GO:0006675; P:mannosyl-inositol phosphorylceramide metabolic process; IMP:SGD.::GO:0032527; P:protein exit from endoplasmic reticulum; IGI:SGD.::GO:0006906; P:vesicle fusion; IDA:SGD.
2Q9P6P1    301   TLG2_SCHPO t-SNARE affecting a late Golgi com...3374e-35     136     28     50GO:0005829; C:cytosol; IDA:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005484; F:SNAP receptor activity; ISS:PomBase.
GO:0006886; P:intracellular protein transport; NAS:PomBase.::GO:0010811; P:positive regulation of cell-substrate adhesion; IMP:PomBase.::GO:0016192; P:vesicle-mediated transport; IC:PomBase.
3Q9SUJ1    331   SYP43_ARATH Syntaxin-43 OS=Arabidopsis thalia...3556e-25     107     28     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005802; C:trans-Golgi network; IDA:TAIR.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0007030; P:Golgi organization; IGI:TAIR.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0009306; P:protein secretion; IGI:TAIR.::GO:1900150; P:regulation of defense response to fungus; IGI:TAIR.::GO:0007034; P:vacuolar transport; IGI:TAIR.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
4O65359    322   SYP41_ARATH Syntaxin-41 OS=Arabidopsis thalia...3524e-24     105     26     44GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005802; C:trans-Golgi network; IDA:TAIR.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
5Q9SWH4    323   SYP42_ARATH Syntaxin-42 OS=Arabidopsis thalia...3459e-21     95.1     27     47GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005802; C:trans-Golgi network; IDA:TAIR.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0007030; P:Golgi organization; IGI:TAIR.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0009306; P:protein secretion; IGI:TAIR.::GO:1900150; P:regulation of defense response to fungus; IGI:TAIR.::GO:0007034; P:vacuolar transport; IGI:TAIR.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
6O14662    325   STX16_HUMAN Syntaxin-16 OS=Homo sapiens (Huma...2502e-16     83.2     26     54GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; TAS:ProtInc.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0031201; C:SNARE complex; TAS:HGNC.
GO:0005484; F:SNAP receptor activity; IDA:HGNC.
GO:0006891; P:intra-Golgi vesicle-mediated transport; TAS:ProtInc.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0042147; P:retrograde transport, endosome to Golgi; IDA:UniProtKB.
7Q8BVI5    326   STX16_MOUSE Syntaxin-16 OS=Mus musculus (Mous...2494e-16     82     27     53GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0042147; P:retrograde transport, endosome to Golgi; ISS:UniProtKB.
8Q54JY7    356   STX7A_DICDI Syntaxin-7A OS=Dictyostelium disc...1130.000000002     62     32     58GO:0030666; C:endocytic vesicle membrane; IDA:dictyBase.::GO:0010008; C:endosome membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0008333; P:endosome to lysosome transport; IDA:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006906; P:vesicle fusion; IDA:dictyBase.
9Q5RBW6    276   STX12_PONAB Syntaxin-12 OS=Pongo abelii (Suma...780.000000003     60.8     36     71GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
10P32854    288   PEP12_YEAST Syntaxin PEP12 OS=Saccharomyces c...900.000000007     60.1     39     66GO:0005768; C:endosome; IMP:SGD.::GO:0005794; C:Golgi apparatus; IMP:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005484; F:SNAP receptor activity; IDA:SGD.
GO:0006896; P:Golgi to vacuole transport; IMP:SGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0000011; P:vacuole inheritance; IMP:SGD.
11Q86Y82    276   STX12_HUMAN Syntaxin-12 OS=Homo sapiens (Huma...770.00000001     59.3     35     70GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045121; C:membrane raft; IDA:BHF-UCL.::GO:0045335; C:phagocytic vesicle; IDA:BHF-UCL.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0033344; P:cholesterol efflux; IDA:BHF-UCL.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0050821; P:protein stabilization; IDA:BHF-UCL.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
12O70439    261   STX7_MOUSE Syntaxin-7 OS=Mus musculus (Mouse)...900.00000005     57.4     27     66GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
13Q24547    291   STX1A_DROME Syntaxin-1A OS=Drosophila melanog...1230.0000002     55.8     28     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; NAS:FlyBase.
GO:0005484; F:SNAP receptor activity; NAS:FlyBase.
GO:0007349; P:cellularization; NAS:FlyBase.::GO:0000910; P:cytokinesis; IMP:FlyBase.::GO:0007482; P:haltere development; IGI:FlyBase.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007317; P:regulation of pole plasm oskar mRNA localization; IMP:FlyBase.::GO:0031629; P:synaptic vesicle fusion to presynaptic membrane; IMP:FlyBase.
14G3V7P1    274   STX12_RAT Syntaxin-12 OS=Rattus norvegicus (R...690.0000002     55.5     35     71GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
15Q9ER00    274   STX12_MOUSE Syntaxin-12 OS=Mus musculus (Mous...690.0000004     54.7     35     71GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
16P61268    288   STX1B_SHEEP Syntaxin-1B OS=Ovis aries (Sheep)...950.0000004     54.7     34     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.::GO:0007268; P:synaptic transmission; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
17P61267    288   STX1B_BOVIN Syntaxin-1B OS=Bos taurus (Bovine...950.0000004     54.7     34     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.::GO:0007268; P:synaptic transmission; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
18P61265    288   STX1B_RAT Syntaxin-1B OS=Rattus norvegicus (R...950.0000004     54.7     34     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.::GO:0017157; P:regulation of exocytosis; IMP:RGD.::GO:0007268; P:synaptic transmission; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IMP:RGD.
19P61264    288   STX1B_MOUSE Syntaxin-1B OS=Mus musculus (Mous...950.0000004     54.7     34     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:MGI.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.::GO:0007268; P:synaptic transmission; IEA:InterPro.
20P61266    288   STX1B_HUMAN Syntaxin-1B OS=Homo sapiens (Huma...950.0000004     54.7     34     58GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0005234; F:extracellular-glutamate-gated ion channel activity; TAS:ProtInc.::GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.::GO:0007268; P:synaptic transmission; TAS:ProtInc.
21P32850    288   STX1A_BOVIN Syntaxin-1A OS=Bos taurus (Bovine...940.0000006     54.3     31     57GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.::GO:0007268; P:synaptic transmission; IEA:InterPro.
22Q3ZBT5    261   STX7_BOVIN Syntaxin-7 OS=Bos taurus (Bovine)....790.0000006     53.9     30     67GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
23O94651    317   PEP12_SCHPO Syntaxin pep12 OS=Schizosaccharom...1130.0000008     53.9     28     52GO:0005783; C:endoplasmic reticulum; IDA:PomBase.::GO:0005794; C:Golgi apparatus; ISS:PomBase.::GO:0016020; C:membrane; IEA:InterPro.
GO:0005484; F:SNAP receptor activity; TAS:PomBase.
GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0016192; P:vesicle-mediated transport; TAS:PomBase.
24Q5R602    261   STX7_PONAB Syntaxin-7 OS=Pongo abelii (Sumatr...790.000001     53.1     30     66GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
25O70257    261   STX7_RAT Syntaxin-7 OS=Rattus norvegicus (Rat...900.000001     52.8     30     70GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IDA:RGD.::GO:0005765; C:lysosomal membrane; IDA:RGD.::GO:0031201; C:SNARE complex; IDA:UniProtKB.
GO:0032403; F:protein complex binding; IDA:RGD.::GO:0005484; F:SNAP receptor activity; IEA:InterPro.::GO:0000149; F:SNARE binding; IPI:RGD.
GO:0008333; P:endosome to lysosome transport; IDA:RGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016079; P:synaptic vesicle exocytosis; TAS:RGD.::GO:0006906; P:vesicle fusion; IDA:RGD.
26Q16623    288   STX1A_HUMAN Syntaxin-1A OS=Homo sapiens (Huma...910.000002     52.8     34     56GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043005; C:neuron projection; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0014047; P:glutamate secretion; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0050796; P:regulation of insulin secretion; TAS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
27O35526    288   STX1A_MOUSE Syntaxin-1A OS=Mus musculus (Mous...950.000002     52.8     33     56GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043005; C:neuron projection; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0030672; C:synaptic vesicle membrane; IDA:MGI.::GO:0070044; C:synaptobrevin 2-SNAP-25-syntaxin-1a complex; IDA:MGI.::GO:0019717; C:synaptosome; IDA:UniProtKB.
GO:0019855; F:calcium channel inhibitor activity; IMP:MGI.::GO:0005484; F:SNAP receptor activity; IEA:InterPro.::GO:0000149; F:SNARE binding; IDA:MGI.
GO:0017156; P:calcium ion-dependent exocytosis; IMP:MGI.::GO:0006886; P:intracellular protein transport; IEA:InterPro.
28P32851    288   STX1A_RAT Syntaxin-1A OS=Rattus norvegicus (R...950.000002     52.8     33     56GO:0042641; C:actomyosin; IDA:RGD.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0030141; C:secretory granule; IDA:UniProtKB.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0070044; C:synaptobrevin 2-SNAP-25-syntaxin-1a complex; IDA:MGI.::GO:0070032; C:synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex; IDA:MGI.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0043008; F:ATP-dependent protein binding; IPI:RGD.::GO:0048306; F:calcium-dependent protein binding; IPI:RGD.::GO:0001948; F:glycoprotein binding; IDA:MGI.::GO:0032028; F:myosin head/neck binding; IPI:RGD.::GO:0030674; F:protein binding, bridging; IPI:RGD.::GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.::GO:0047485; F:protein N-terminus binding; IDA:RGD.::GO:0005484; F:SNAP receptor activity; IEA:InterPro.::GO:0000149; F:SNARE binding; IDA:MGI.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0045921; P:positive regulation of exocytosis; IDA:RGD.::GO:0001956; P:positive regulation of neurotransmitter secretion; IMP:RGD.::GO:0009629; P:response to gravity; IDA:RGD.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; IEP:UniProtKB.
29O15400    261   STX7_HUMAN Syntaxin-7 OS=Homo sapiens (Human)...700.000002     52.4     30     70GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:ProtInc.
30Q5R4L2    288   STX1A_PONAB Syntaxin-1A OS=Pongo abelii (Suma...780.000002     52.4     36     60GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.::GO:0007268; P:synaptic transmission; IEA:InterPro.
31O16000    291   STX1A_CAEEL Syntaxin-1A homolog OS=Caenorhabd...1070.000002     52.4     31     52GO:0030424; C:axon; IDA:WormBase.::GO:0016323; C:basolateral plasma membrane; IDA:WormBase.::GO:0030425; C:dendrite; IDA:WormBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase.
GO:0005484; F:SNAP receptor activity; IEA:InterPro.::GO:0042302; F:structural constituent of cuticle; IEA:UniProtKB-KW.
GO:0019722; P:calcium-mediated signaling; NAS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0008286; P:insulin receptor signaling pathway; IMP:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0040011; P:locomotion; IMP:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007269; P:neurotransmitter secretion; IMP:UniProtKB.::GO:0040014; P:regulation of multicellular organism growth; IMP:UniProtKB.::GO:0007271; P:synaptic transmission, cholinergic; IMP:WormBase.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
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