UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YOL018C

Length:

397

Number of sequences:

5887

Description:

YOL018C TLG2 SGDID:S000005378, Chr XV from 292074-290881, Genome Release 64-1-1, reverse complement, Verified ORF, "Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds Vps45p, which prevents Tlg2p degradation and also facilitates t-SNARE complex formation; homologous to mammalian SNARE protein syntaxin 16 (Sx16)"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	O16000	291	STX1A_CAEEL Syntaxin-1A homolog OS=Caenorhabd...	107	0.000002	52.4	31	52	GO:0030424; C:axon; IDA:WormBase.::GO:0016323; C:basolateral plasma membrane; IDA:WormBase.::GO:0030425; C:dendrite; IDA:WormBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase.
									GO:0005484; F:SNAP receptor activity; IEA:InterPro.::GO:0042302; F:structural constituent of cuticle; IEA:UniProtKB-KW.
									GO:0019722; P:calcium-mediated signaling; NAS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0008286; P:insulin receptor signaling pathway; IMP:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0040011; P:locomotion; IMP:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007269; P:neurotransmitter secretion; IMP:UniProtKB.::GO:0040014; P:regulation of multicellular organism growth; IMP:UniProtKB.::GO:0007271; P:synaptic transmission, cholinergic; IMP:WormBase.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
32	Q16932	290	STX_APLCA Syntaxin OS=Aplysia californica (Ca...	99	0.000003	52	29	58	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0005484; F:SNAP receptor activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
33	Q20024	306	STX1_CAEEL Putative syntaxin-1 OS=Caenorhabdi...	129	0.00004	48.9	28	50	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0005484; F:SNAP receptor activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; ISS:UniProtKB.
34	P39926	295	SSO2_YEAST Protein SSO2 OS=Saccharomyces cere...	119	0.00006	48.1	29	55	GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.::GO:0005628; C:prospore membrane; IDA:SGD.
									GO:0070300; F:phosphatidic acid binding; IDA:SGD.::GO:0005484; F:SNAP receptor activity; IPI:SGD.
									GO:0031321; P:ascospore-type prospore assembly; IGI:SGD.::GO:0006893; P:Golgi to plasma membrane transport; TAS:SGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006906; P:vesicle fusion; TAS:SGD.
35	Q20797	413	STX3_CAEEL Putative syntaxin-3 OS=Caenorhabdi...	150	0.0001	47.8	27	47	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0005484; F:SNAP receptor activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; ISS:UniProtKB.
36	Q9LK09	347	SYP32_ARATH Syntaxin-32 OS=Arabidopsis thalia...	98	0.0001	47	29	51	GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0005484; F:SNAP receptor activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
37	Q12241	283	VAM3_YEAST Syntaxin VAM3 OS=Saccharomyces cer...	74	0.0002	46.6	32	59	GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031201; C:SNARE complex; IDA:SGD.
									GO:0042803; F:protein homodimerization activity; IDA:SGD.::GO:0005484; F:SNAP receptor activity; IDA:SGD.
									GO:0000046; P:autophagic vacuole fusion; IMP:SGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0034727; P:piecemeal microautophagy of nucleus; IMP:SGD.::GO:0042144; P:vacuole fusion, non-autophagic; IDA:SGD.::GO:0048278; P:vesicle docking; IGI:SGD.::GO:0051469; P:vesicle fusion with vacuole; IGI:SGD.
38	P93654	268	SYP22_ARATH Syntaxin-22 OS=Arabidopsis thalia...	79	0.001	43.9	29	56	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0009705; C:plant-type vacuole membrane; IDA:TAIR.
									GO:0005484; F:SNAP receptor activity; IEA:InterPro.
									GO:0009660; P:amyloplast organization; IMP:TAIR.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0009959; P:negative gravitropism; IMP:TAIR.::GO:0010118; P:stomatal movement; IMP:TAIR.::GO:0007033; P:vacuole organization; IGI:TAIR.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
39	O64791	303	SY124_ARATH Syntaxin-124 OS=Arabidopsis thali...	118	0.002	43.9	28	53	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0030133; C:transport vesicle; IDA:TAIR.
									GO:0005484; F:SNAP receptor activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0009860; P:pollen tube growth; IDA:TAIR.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
40	P70452	298	STX4_MOUSE Syntaxin-4 OS=Mus musculus (Mouse)...	169	0.002	43.5	24	48	GO:0016323; C:basolateral plasma membrane; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043219; C:lateral loop; IDA:BHF-UCL.::GO:0035749; C:myelin sheath adaxonal region; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB.
									GO:0005484; F:SNAP receptor activity; IEA:InterPro.::GO:0000149; F:SNARE binding; IPI:UniProtKB.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.
41	Q08850	298	STX4_RAT Syntaxin-4 OS=Rattus norvegicus (Rat...	169	0.003	42.7	24	48	GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0016323; C:basolateral plasma membrane; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042383; C:sarcolemma; IDA:RGD.::GO:0031201; C:SNARE complex; IDA:UniProtKB.
									GO:0017137; F:Rab GTPase binding; IPI:RGD.::GO:0005484; F:SNAP receptor activity; IEA:InterPro.::GO:0000149; F:SNARE binding; IPI:RGD.::GO:0030507; F:spectrin binding; IPI:RGD.
									GO:0006944; P:cellular membrane fusion; IDA:RGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006461; P:protein complex assembly; IDA:RGD.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; IDA:RGD.
42	A8WVD0	293	STX1A_CAEBR Syntaxin-1A OS=Caenorhabditis bri...	87	0.003	42.7	33	52	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0005484; F:SNAP receptor activity; IEA:InterPro.::GO:0042302; F:structural constituent of cuticle; IEA:UniProtKB-KW.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0040011; P:locomotion; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007269; P:neurotransmitter secretion; ISS:UniProtKB.::GO:0040014; P:regulation of multicellular organism growth; ISS:UniProtKB.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
43	Q12846	297	STX4_HUMAN Syntaxin-4 OS=Homo sapiens (Human)...	169	0.004	42.4	23	48	GO:0016323; C:basolateral plasma membrane; IDA:HGNC.::GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0001950; C:plasma membrane enriched fraction; IDA:UniProtKB.::GO:0042581; C:specific granule; IDA:UniProtKB.::GO:0005773; C:vacuole; TAS:HGNC.
									GO:0005484; F:SNAP receptor activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
44	Q01590	340	SED5_YEAST Integral membrane protein SED5 OS=...	62	0.004	42.7	29	60	GO:0005801; C:cis-Golgi network; IDA:SGD.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IDA:SGD.::GO:0031201; C:SNARE complex; IDA:SGD.
									GO:0005484; F:SNAP receptor activity; IDA:SGD.
									GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0006891; P:intra-Golgi vesicle-mediated transport; IMP:SGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0048280; P:vesicle fusion with Golgi apparatus; IMP:SGD.
45	Q39233	279	SYP21_ARATH Syntaxin-21 OS=Arabidopsis thalia...	79	0.005	42	30	54	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0030140; C:trans-Golgi network transport vesicle; IDA:TAIR.
									GO:0005484; F:SNAP receptor activity; IDA:TAIR.
									GO:0006896; P:Golgi to vacuole transport; TAS:TAIR.::GO:0045324; P:late endosome to vacuole transport; IMP:TAIR.::GO:0006623; P:protein targeting to vacuole; IDA:TAIR.
46	P32867	290	SSO1_YEAST Protein SSO1 OS=Saccharomyces cere...	147	0.006	42	27	52	GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.::GO:0005628; C:prospore membrane; IDA:SGD.::GO:0031201; C:SNARE complex; IDA:SGD.
									GO:0070300; F:phosphatidic acid binding; IDA:SGD.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:SGD.::GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:SGD.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:SGD.::GO:0005484; F:SNAP receptor activity; IDA:SGD.
									GO:0031321; P:ascospore-type prospore assembly; IMP:SGD.::GO:0006893; P:Golgi to plasma membrane transport; TAS:SGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006906; P:vesicle fusion; IDA:SGD.
47	Q54X86	286	STX7B_DICDI Probable syntaxin-7B OS=Dictyoste...	91	0.01	41.2	30	54	GO:0005768; C:endosome; ISS:dictyBase.::GO:0016021; C:integral to membrane; ISS:dictyBase.
48	Q9FFK1	336	SYP31_ARATH Syntaxin-31 OS=Arabidopsis thalia...	92	0.022	40.4	26	48	GO:0009504; C:cell plate; IDA:TAIR.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:TAIR.
									GO:0005484; F:SNAP receptor activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
49	Q9SRV7	306	SY131_ARATH Putative syntaxin-131 OS=Arabidop...	84	0.026	40	31	58	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
									GO:0005484; F:SNAP receptor activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
50	P83528	122	STX5_CAEEL Putative syntaxin C15C7.1 OS=Caeno...	101	0.045	37.4	24	53	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0005484; F:SNAP receptor activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; ISS:UniProtKB.
51	Q24509	467	STX5_DROME Syntaxin-5 OS=Drosophila melanogas...	75	0.068	38.9	28	61	GO:0005801; C:cis-Golgi network; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0000139; C:Golgi membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0005484; F:SNAP receptor activity; IEA:InterPro.
									GO:0000902; P:cell morphogenesis; IMP:FlyBase.::GO:0008283; P:cell proliferation; IMP:FlyBase.::GO:0000910; P:cytokinesis; IMP:FlyBase.::GO:0007030; P:Golgi organization; IMP:FlyBase.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0045930; P:negative regulation of mitotic cell cycle; IMP:FlyBase.::GO:0007269; P:neurotransmitter secretion; NAS:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0009306; P:protein secretion; IMP:FlyBase.::GO:0060305; P:regulation of cell diameter; IMP:FlyBase.
52	Q3SWZ3	297	STX4_BOVIN Syntaxin-4 OS=Bos taurus (Bovine)....	154	0.099	38.1	25	49	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0005484; F:SNAP receptor activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
53	Q13277	289	STX3_HUMAN Syntaxin-3 OS=Homo sapiens (Human)...	66	0.2	37	32	59	GO:0016324; C:apical plasma membrane; IDA:HGNC.::GO:0042582; C:azurophil granule; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0030426; C:growth cone; ISS:HGNC.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.::GO:0001950; C:plasma membrane enriched fraction; IDA:UniProtKB.::GO:0031201; C:SNARE complex; ISS:HGNC.::GO:0042581; C:specific granule; IDA:UniProtKB.
									GO:0050544; F:arachidonic acid binding; ISS:HGNC.::GO:0005484; F:SNAP receptor activity; IEA:InterPro.
									GO:0034599; P:cellular response to oxidative stress; IDA:BHF-UCL.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0031175; P:neuron projection development; ISS:HGNC.::GO:0006836; P:neurotransmitter transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
54	Q96NA8	513	TSNA1_HUMAN t-SNARE domain-containing protein...	101	0.26	37	31	51	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
55	Q00262	289	STX2_MOUSE Syntaxin-2 OS=Mus musculus (Mouse)...	110	0.27	36.6	27	50	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0048306; F:calcium-dependent protein binding; IPI:HGNC.::GO:0005484; F:SNAP receptor activity; IEA:InterPro.
									GO:0007340; P:acrosome reaction; IDA:HGNC.::GO:0006886; P:intracellular protein transport; IEA:InterPro.
56	P50279	290	STX2_RAT Syntaxin-2 OS=Rattus norvegicus (Rat...	71	0.3	36.6	30	56	GO:0016021; C:integral to membrane; TAS:RGD.::GO:0030496; C:midbody; IDA:RGD.::GO:0031201; C:SNARE complex; TAS:RGD.::GO:0030133; C:transport vesicle; IDA:RGD.
									GO:0005484; F:SNAP receptor activity; IEA:InterPro.::GO:0000149; F:SNARE binding; IMP:RGD.
									GO:0000920; P:cytokinetic cell separation; IMP:RGD.::GO:0048546; P:digestive tract morphogenesis; IMP:RGD.::GO:0030855; P:epithelial cell differentiation; IMP:RGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0030033; P:microvillus assembly; IDA:RGD.::GO:0045026; P:plasma membrane fusion; IMP:RGD.::GO:0006906; P:vesicle fusion; TAS:RGD.::GO:0006903; P:vesicle targeting; TAS:RGD.
57	Q9SXB0	298	SY125_ARATH Syntaxin-125 OS=Arabidopsis thali...	93	0.45	36.2	26	56	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0005484; F:SNAP receptor activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
58	Q8K1E0	355	STX5_MOUSE Syntaxin-5 OS=Mus musculus (Mouse)...	254	0.54	35.8	24	47	GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; TAS:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0005484; F:SNAP receptor activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; TAS:MGI.
59	Q946Y7	245	SYP61_ARATH Syntaxin-61 OS=Arabidopsis thalia...	89	0.6	35.4	22	56	GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005802; C:trans-Golgi network; IDA:TAIR.
									GO:0005484; F:SNAP receptor activity; TAS:TAIR.
									GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0048193; P:Golgi vesicle transport; IEA:InterPro.::GO:0006886; P:intracellular protein transport; IDA:TAIR.
60	Q08849	289	STX3_RAT Syntaxin-3 OS=Rattus norvegicus (Rat...	66	0.78	35.4	30	59	GO:0030426; C:growth cone; IDA:HGNC.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031201; C:SNARE complex; IDA:HGNC.
									GO:0050544; F:arachidonic acid binding; IDA:HGNC.::GO:0005484; F:SNAP receptor activity; IEA:InterPro.
									GO:0006944; P:cellular membrane fusion; IDA:RGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0031175; P:neuron projection development; IDA:HGNC.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; TAS:RGD.
61	Q64704	289	STX3_MOUSE Syntaxin-3 OS=Mus musculus (Mouse)...	66	0.83	35	30	59	GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0005484; F:SNAP receptor activity; IEA:InterPro.
									GO:0006887; P:exocytosis; IMP:MGI.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.

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