rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q08109 | 551 | HRD1_YEAST ERAD-associated E3 ubiquitin-prote... | 551 | 0 | 1133 | 100 | 100 | GO:0000839; C:Hrd1p ubiquitin ligase ERAD-L complex; IDA:SGD.::GO:0000838; C:Hrd1p ubiquitin ligase ERAD-M complex; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030433; P:ER-associated protein catabolic process; IPI:SGD.::GO:0031505; P:fungal-type cell wall organization; IGI:SGD. | 2 | Q75CC8 | 575 | HRD1_ASHGO ERAD-associated E3 ubiquitin-prote... | 413 | 7e-56 | 202 | 32 | 53 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 3 | O74757 | 677 | HRD1_SCHPO ERAD-associated E3 ubiquitin-prote... | 486 | 4e-28 | 122 | 25 | 41 | GO:0005938; C:cell cortex; IDA:PomBase.::GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:PomBase.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030433; P:ER-associated protein catabolic process; IMP:PomBase.::GO:0010620; P:negative regulation of transcription by transcription factor catabolism; IMP:PomBase. | 4 | Q803I8 | 625 | SYVN1_DANRE E3 ubiquitin-protein ligase synov... | 369 | 1e-25 | 115 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 5 | Q86TM6 | 617 | SYVN1_HUMAN E3 ubiquitin-protein ligase synov... | 369 | 2e-25 | 114 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB. | 6 | Q9DBY1 | 612 | SYVN1_MOUSE E3 ubiquitin-protein ligase synov... | 367 | 2e-25 | 114 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI. | 7 | Q5XHH7 | 595 | SYVNB_XENLA E3 ubiquitin-protein ligase synov... | 369 | 5e-23 | 106 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 8 | Q6NRL6 | 605 | SYVNA_XENLA E3 ubiquitin-protein ligase synov... | 369 | 1e-22 | 105 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 9 | Q95SP2 | 626 | HRD1_DROME E3 ubiquitin-protein ligase HRD1 O... | 368 | 1e-20 | 99.8 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB. | 10 | Q20798 | 610 | HRD1_CAEEL E3 ubiquitin-protein ligase hrd-1 ... | 343 | 1e-19 | 95.9 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 11 | A8Y4B2 | 622 | HRD1_CAEBR E3 ubiquitin-protein ligase hrd-1 ... | 343 | 2e-18 | 92.8 | 24 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 12 | Q9UKV5 | 643 | AMFR2_HUMAN E3 ubiquitin-protein ligase AMFR ... | 75 | 0.000001 | 55.1 | 32 | 55 | GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0000299; C:integral to membrane of membrane fraction; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.::GO:0051259; P:protein oligomerization; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB. | 13 | Q9R049 | 643 | AMFR_MOUSE E3 ubiquitin-protein ligase AMFR O... | 75 | 0.000001 | 54.7 | 32 | 55 | GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB. | 14 | Q9Y3C5 | 154 | RNF11_HUMAN RING finger protein 11 OS=Homo sa... | 56 | 0.000005 | 50.4 | 41 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; TAS:ProtInc. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB. | 15 | Q08DI6 | 154 | RNF11_BOVIN RING finger protein 11 OS=Bos tau... | 56 | 0.000005 | 50.4 | 41 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 16 | Q9QYK7 | 154 | RNF11_MOUSE RING finger protein 11 OS=Mus mus... | 56 | 0.000005 | 50.1 | 41 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IPI:MGI. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 17 | Q9Y7K6 | 741 | YGI4_SCHPO Uncharacterized RING finger protei... | 59 | 0.000005 | 53.1 | 37 | 54 | GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006325; P:chromatin organization; ISS:PomBase.::GO:0006342; P:chromatin silencing; ISS:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:PomBase. | 18 | Q7T037 | 757 | RF12B_XENLA E3 ubiquitin-protein ligase RNF12... | 108 | 0.00001 | 52 | 32 | 46 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000578; P:embryonic axis specification; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 19 | Q9H6Y7 | 350 | RN167_HUMAN E3 ubiquitin-protein ligase RNF16... | 160 | 0.00001 | 51.2 | 26 | 40 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045786; P:negative regulation of cell cycle; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB. | 20 | Q9NVW2 | 624 | RNF12_HUMAN E3 ubiquitin-protein ligase RLIM ... | 88 | 0.00001 | 51.6 | 35 | 47 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0017053; C:transcriptional repressor complex; NAS:UniProtKB. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; NAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060816; P:random inactivation of X chromosome; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 21 | Q641J8 | 622 | RF12A_XENLA E3 ubiquitin-protein ligase RNF12... | 88 | 0.00001 | 51.6 | 34 | 45 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000578; P:embryonic axis specification; IMP:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB. | 22 | Q9DBU5 | 667 | RNF6_MOUSE E3 ubiquitin-protein ligase RNF6 O... | 81 | 0.00001 | 51.6 | 28 | 48 | GO:0030424; C:axon; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016605; C:PML body; IDA:MGI. | | | | | | | | | | GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030517; P:negative regulation of axon extension; IMP:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0044314; P:protein K27-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IMP:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:MGI. | 23 | Q07G42 | 639 | RNF12_XENTR E3 ubiquitin-protein ligase RNF12... | 88 | 0.00002 | 51.2 | 34 | 45 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000578; P:embryonic axis specification; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 24 | Q8VYC8 | 578 | RIN2_ARATH E3 ubiquitin protein ligase RIN2 O... | 82 | 0.00003 | 50.4 | 34 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009626; P:plant-type hypersensitive response; IEA:UniProtKB-KW.::GO:0034052; P:positive regulation of plant-type hypersensitive response; IGI:TAIR. | 25 | Q8LPN7 | 328 | RNG1L_ARATH E3 ubiquitin-protein ligase RING1... | 97 | 0.00004 | 49.3 | 29 | 44 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 26 | Q9Y252 | 685 | RNF6_HUMAN E3 ubiquitin-protein ligase RNF6 O... | 88 | 0.00004 | 50.1 | 28 | 44 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050681; F:androgen receptor binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030517; P:negative regulation of axon extension; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0044314; P:protein K27-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 27 | Q8RXD3 | 310 | AIP2_ARATH E3 ubiquitin-protein ligase AIP2 O... | 78 | 0.00004 | 49.3 | 33 | 45 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0009788; P:negative regulation of abscisic acid mediated signaling pathway; IMP:UniProtKB. | 28 | Q9WTV7 | 600 | RNF12_MOUSE E3 ubiquitin-protein ligase RLIM ... | 88 | 0.00005 | 50.1 | 34 | 47 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0060816; P:random inactivation of X chromosome; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB. | 29 | Q86XS8 | 419 | GOLI_HUMAN E3 ubiquitin-protein ligase RNF130... | 144 | 0.00005 | 49.7 | 26 | 42 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 30 | Q9M0R7 | 132 | ATL39_ARATH RING-H2 finger protein ATL39 OS=A... | 57 | 0.00005 | 47 | 35 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 31 | Q8W4Q5 | 577 | RIN3_ARATH E3 ubiquitin protein ligase RIN3 O... | 74 | 0.00007 | 49.3 | 32 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009626; P:plant-type hypersensitive response; IEA:UniProtKB-KW.::GO:0034052; P:positive regulation of plant-type hypersensitive response; IGI:TAIR. |