Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL013C
Length:
551
Number of sequences:
5887
Description:
YOL013C HRD1 SGDID:S000005373, Chr XV from 303035-301380, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q9LZJ6    257   ATL5_ARATH RING-H2 finger protein ATL5 OS=Ara...560.003     43.5     30     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006461; P:protein complex assembly; TAS:TAIR.
92Q9P0P0    153   RN181_HUMAN E3 ubiquitin-protein ligase RNF18...340.003     42     41     68
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
93Q9CY62    165   RN181_MOUSE E3 ubiquitin-protein ligase RNF18...680.003     42     28     49
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
94Q9C1X4    513   YKW3_SCHPO Uncharacterized RING finger protei...650.003     43.9     32     46
GO:0008270; F:zinc ion binding; IEA:InterPro.
95Q08CG8    448   RNF44_DANRE RING finger protein 44 OS=Danio r...620.003     43.5     27     50
GO:0008270; F:zinc ion binding; IEA:InterPro.
96Q66HG0    380   RNF13_RAT E3 ubiquitin-protein ligase RNF13 O...810.004     43.5     26     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; ISS:UniProtKB.::GO:0005765; C:lysosomal membrane; ISS:UniProtKB.::GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
97Q5SWK7    663   RN145_MOUSE RING finger protein 145 OS=Mus mu...720.004     43.9     31     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
98O54965    381   RNF13_MOUSE E3 ubiquitin-protein ligase RNF13...810.004     43.5     26     48GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IDA:UniProtKB.::GO:0005765; C:lysosomal membrane; IDA:UniProtKB.::GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
99Q9VE61    147   RN181_DROME E3 ubiquitin-protein ligase RNF18...450.004     41.6     33     60
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
100Q9SLC3    236   ATL41_ARATH E3 ubiquitin-protein ligase ATL41...780.004     42.7     29     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
101Q7ZWF4    685   RN145_DANRE RING finger protein 145 OS=Danio ...710.004     43.9     30     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
102Q6NRG0    532   RNF8B_XENLA E3 ubiquitin-protein ligase RNF8-...1010.004     43.5     31     44GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:InterPro.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
103Q9FL07    376   ATL46_ARATH RING-H2 finger protein ATL46 OS=A...1040.004     43.1     26     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
104Q7TMV1    668   RN139_MOUSE E3 ubiquitin-protein ligase RNF13...890.005     43.5     25     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031396; P:regulation of protein ubiquitination; ISS:UniProtKB.
105Q91YL2    313   RN126_MOUSE RING finger protein 126 OS=Mus mu...280.005     42.7     46     75
GO:0008270; F:zinc ion binding; IEA:InterPro.
106O60683    326   PEX10_HUMAN Peroxisome biogenesis factor 10 O...820.005     42.7     23     41GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016558; P:protein import into peroxisome matrix; IDA:UniProtKB.
107Q86Y13    1208   DZIP3_HUMAN E3 ubiquitin-protein ligase DZIP3...560.005     43.5     36     48GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0019902; F:phosphatase binding; IDA:UniProtKB.::GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.::GO:0003723; F:RNA binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
108O88196    1979   TTC3_MOUSE E3 ubiquitin-protein ligase TTC3 O...570.005     43.5     37     47GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005773; C:vacuole; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010771; P:negative regulation of cell morphogenesis involved in differentiation; IDA:MGI.::GO:0045665; P:negative regulation of neuron differentiation; IDA:MGI.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
109O22255    227   ATL64_ARATH RING-H2 finger protein ATL64 OS=A...560.005     42.4     32     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
110Q6AXU4    165   RN181_RAT E3 ubiquitin-protein ligase RNF181 ...340.005     41.6     38     68
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
111Q8LBA0    223   NIPL2_ARATH NEP1-interacting protein-like 2 O...570.005     42.4     35     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0010200; P:response to chitin; IEP:TAIR.
112Q8BI21    518   RNF38_MOUSE RING finger protein 38 OS=Mus mus...770.006     43.1     27     45
GO:0008270; F:zinc ion binding; IEA:InterPro.
113Q9H0F5    515   RNF38_HUMAN RING finger protein 38 OS=Homo sa...770.006     43.1     29     48
GO:0008270; F:zinc ion binding; IEA:InterPro.
114Q9FPH0    376   XB34_ARATH Putative E3 ubiquitin-protein liga...760.006     42.7     29     51
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
115Q5SSZ7    913   ZNRF3_MOUSE Zinc/RING finger protein 3 OS=Mus...1150.006     43.1     27     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
116Q6IRP0    312   R126B_XENLA RING finger protein 126-B OS=Xeno...280.006     42.7     46     71
GO:0008270; F:zinc ion binding; IEA:InterPro.
117Q3T0W3    153   RN181_BOVIN E3 ubiquitin-protein ligase RNF18...340.007     40.8     38     68
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
118Q7TPV2    1204   DZIP3_MOUSE E3 ubiquitin-protein ligase DZIP3...560.007     43.1     36     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
119Q6DIP3    311   RN126_XENTR RING finger protein 126 OS=Xenopu...280.007     42.4     46     71
GO:0008270; F:zinc ion binding; IEA:InterPro.
120Q9SLC4    217   ATL40_ARATH RING-H2 finger protein ATL40 OS=A...520.007     41.6     31     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
121Q810L3    664   CHFR_MOUSE E3 ubiquitin-protein ligase CHFR O...550.008     42.7     40     44GO:0016605; C:PML body; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:MGI.
records
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