UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YOL013C

Length:

551

Number of sequences:

5887

Description:

YOL013C HRD1 SGDID:S000005373, Chr XV from 303035-301380, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
391	Q8HXH0	718	LONF3_MACFA LON peptidase N-terminal domain a...	30	7.2	33.1	37	60
									GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:InterPro.
392	Q9WTZ1	113	RBX2_MOUSE RING-box protein 2 OS=Mus musculus...	24	7.4	31.2	33	63	GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
									GO:0019788; F:NEDD8 ligase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:MGI.::GO:0006916; P:anti-apoptosis; IDA:MGI.::GO:0008637; P:apoptotic mitochondrial changes; IDA:MGI.::GO:0008631; P:induction of apoptosis by oxidative stress; IDA:MGI.::GO:0045116; P:protein neddylation; ISS:UniProtKB.
393	Q9UBF6	113	RBX2_HUMAN RING-box protein 2 OS=Homo sapiens...	24	7.4	31.2	33	63	GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0005634; C:nucleus; NAS:UniProtKB.
									GO:0005507; F:copper ion binding; TAS:ProtInc.::GO:0019788; F:NEDD8 ligase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
									GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0008631; P:induction of apoptosis by oxidative stress; TAS:ProtInc.::GO:0045116; P:protein neddylation; IDA:UniProtKB.::GO:0051775; P:response to redox state; TAS:ProtInc.
394	Q8VC56	488	RNF8_MOUSE E3 ubiquitin-protein ligase RNF8 O...	90	7.6	33.1	29	40	GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; IMP:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; IMP:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
395	Q5FWL3	317	RNF41_XENLA E3 ubiquitin-protein ligase NRDP1...	68	7.8	32.7	26	44
									GO:0031386; F:protein tag; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
396	Q7XLY8	383	ATL41_ORYSJ E3 ubiquitin-protein ligase Os04g...	53	8.1	32.7	26	43	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
397	Q08273	121	RBX1_YEAST RING-box protein HRT1 OS=Saccharom...	26	8.8	31.2	35	50	GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:SGD.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:SGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:SGD.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.
398	Q6PC78	194	RN185_DANRE E3 ubiquitin-protein ligase RNF18...	34	8.9	32	35	53	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
									GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.
399	Q6P9F5	258	TRI40_HUMAN Tripartite motif-containing prote...	73	9.2	32.3	26	41	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0008270; F:zinc ion binding; IEA:InterPro.
400	Q91T40	162	LAP_LSDV E3 ubiquitin-protein ligase LAP OS=L...	63	9.6	31.6	33	46	GO:0044174; C:host cell endosome; IEA:UniProtKB-KW.::GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.
401	Q8TBB1	728	LNX1_HUMAN E3 ubiquitin-protein ligase LNX OS...	60	9.7	32.7	32	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008270; F:zinc ion binding; IEA:InterPro.

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