Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL013C
Length:
551
Number of sequences:
5887
Description:
YOL013C HRD1 SGDID:S000005373, Chr XV from 303035-301380, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q8W4Q5    577   RIN3_ARATH E3 ubiquitin protein ligase RIN3 O...740.00007     49.3     32     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009626; P:plant-type hypersensitive response; IEA:UniProtKB-KW.::GO:0034052; P:positive regulation of plant-type hypersensitive response; IGI:TAIR.
32P36096    758   TUL1_YEAST Transmembrane E3 ubiquitin-protein...570.0001     48.9     37     51GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:SGD.
33Q8VEM1    419   GOLI_MOUSE E3 ubiquitin-protein ligase RNF130...1440.0001     48.5     26     42GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016021; C:integral to membrane; NAS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
34Q6Y290    419   GOLI_RAT E3 ubiquitin-protein ligase RNF130 O...1050.0001     48.1     28     44GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
35Q9XF63    324   ATL3_ARATH RING-H2 finger protein ATL3 OS=Ara...620.0001     48.1     37     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
36O43085    695   DSC1_SCHPO DSC E3 ubiquitin ligase complex su...680.0001     48.5     32     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:PomBase.
37O55176    578   PJA1_MOUSE E3 ubiquitin-protein ligase Praja-...780.0002     48.1     28     45GO:0005737; C:cytoplasm; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IDA:MGI.
38P0CH30    338   RING1_GOSHI E3 ubiquitin-protein ligase RING1...770.0002     47.4     32     48
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
39Q8NG27    643   PJA1_HUMAN E3 ubiquitin-protein ligase Praja-...780.0002     47.8     28     45
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
40Q9ZV51    181   ATL56_ARATH RING-H2 finger protein ATL56 OS=A...560.0002     45.8     36     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
41Q9D0C1    305   RN115_MOUSE E3 ubiquitin-protein ligase RNF11...1340.0002     47     28     39GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
42Q9M0C3    176   ATL14_ARATH RING-H2 finger protein ATL14 OS=A...570.0003     45.4     35     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010200; P:response to chitin; IEP:TAIR.
43Q5M974    156   RN181_XENTR E3 ubiquitin-protein ligase RNF18...690.0003     45.1     30     51
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
44Q91XF4    347   RN167_MOUSE E3 ubiquitin-protein ligase RNF16...1560.0003     47     29     43GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
45Q5XIL0    349   RN167_RAT E3 ubiquitin-protein ligase RNF167 ...1560.0003     47     29     43GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
46Q0IJ20    695   RN145_XENTR RING finger protein 145 OS=Xenopu...1240.0004     47     22     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
47Q8LE94    231   RING3_ARATH E3 ubiquitin-protein ligase At3g0...580.0004     45.8     34     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
48Q9LUZ9    308   ATL63_ARATH RING-H2 finger protein ATL63 OS=A...560.0004     46.2     32     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
49Q90972    381   RNF13_CHICK E3 ubiquitin-protein ligase RNF13...930.0005     46.2     26     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
50Q6GPV5    156   RN181_XENLA E3 ubiquitin-protein ligase RNF18...690.0005     44.3     29     51
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
51P90859    564   HRDL1_CAEEL E3 ubiquitin-protein ligase hrd-l...770.0005     46.6     30     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0043526; P:neuroprotection; IMP:UniProtKB.
52A8WWR3    578   HRDL1_CAEBR E3 ubiquitin-protein ligase hrd-l...600.0005     46.2     35     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043526; P:neuroprotection; ISS:UniProtKB.
53P30631    161   YOUD_CAEEL Uncharacterized RING finger protei...780.0006     43.9     33     44
GO:0008270; F:zinc ion binding; IEA:InterPro.
54Q9ULV8    474   CBLC_HUMAN Signal transduction protein CBL-C ...1210.0007     45.8     32     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005154; F:epidermal growth factor receptor binding; IDA:BHF-UCL.::GO:0001784; F:phosphotyrosine binding; IDA:BHF-UCL.::GO:0017124; F:SH3 domain binding; IDA:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:BHF-UCL.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
55Q2KHN1    245   RN151_HUMAN RING finger protein 151 OS=Homo s...380.0008     45.1     47     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
56P29836    676   ICP0_BHV1K E3 ubiquitin-protein ligase ICP0 O...550.0008     45.8     33     51
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
57P29128    676   ICP0_BHV1J E3 ubiquitin-protein ligase ICP0 O...550.0009     45.8     33     51
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
58O43164    708   PJA2_HUMAN E3 ubiquitin-protein ligase Praja-...550.0009     45.8     35     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0034236; F:protein kinase A catalytic subunit binding; IMP:UniProtKB.::GO:0034237; F:protein kinase A regulatory subunit binding; IMP:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007616; P:long-term memory; ISS:UniProtKB.::GO:0010738; P:regulation of protein kinase A signaling cascade; IMP:UniProtKB.
59Q5R4R1    708   PJA2_PONAB E3 ubiquitin-protein ligase Praja-...550.001     45.8     35     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0034236; F:protein kinase A catalytic subunit binding; ISS:UniProtKB.::GO:0034237; F:protein kinase A regulatory subunit binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007616; P:long-term memory; ISS:UniProtKB.::GO:0010738; P:regulation of protein kinase A signaling cascade; ISS:UniProtKB.
60Q80U04    707   PJA2_MOUSE E3 ubiquitin-protein ligase Praja-...550.001     45.8     35     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0034236; F:protein kinase A catalytic subunit binding; ISS:UniProtKB.::GO:0034237; F:protein kinase A regulatory subunit binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007616; P:long-term memory; ISS:UniProtKB.::GO:0010738; P:regulation of protein kinase A signaling cascade; ISS:UniProtKB.
61Q0VD51    380   RNF13_BOVIN E3 ubiquitin-protein ligase RNF13...810.001     45.1     27     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; ISS:UniProtKB.::GO:0005765; C:lysosomal membrane; ISS:UniProtKB.::GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
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