Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL013C
Length:
551
Number of sequences:
5887
Description:
YOL013C HRD1 SGDID:S000005373, Chr XV from 303035-301380, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301Q8LF65    235   ATL17_ARATH RING-H2 finger protein ATL17 OS=A...630.51     36.2     25     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0010200; P:response to chitin; IEP:TAIR.
302Q8H7N9    353   ATL31_ORYSJ E3 ubiquitin-protein ligase Os03g...530.57     36.6     30     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
303P0C034    251   ATL10_ARATH RING-H2 finger protein ATL10 OS=A...560.58     36.2     29     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
304Q5UPZ3    659   YR311_MIMIV Putative RING finger protein R311...410.6     36.6     32     61
GO:0008270; F:zinc ion binding; IEA:InterPro.
305Q08CN9    217   ZNRF2_DANRE E3 ubiquitin-protein ligase ZNRF2...550.65     35.8     31     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
306Q9P7E1    583   YOF7_SCHPO Uncharacterized RING finger protei...590.74     36.2     32     47GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
307Q9FG21    197   ATL71_ARATH Putative RING-H2 finger protein A...640.76     35.4     28     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
308Q6NQG7    219   ATL78_ARATH RING-H2 finger protein ATL78 OS=A...560.83     35.4     30     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
309Q86Y01    620   DTX1_HUMAN E3 ubiquitin-protein ligase DTX1 O...890.83     36.2     29     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005112; F:Notch binding; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045665; P:negative regulation of neuron differentiation; IGI:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0008593; P:regulation of Notch signaling pathway; IGI:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
310Q5NCC9    485   TRI58_MOUSE Tripartite motif-containing prote...1150.86     36.2     23     37GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
311Q4FE47    462   XB35_ARATH Putative E3 ubiquitin-protein liga...700.89     35.8     26     46
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
312P38748    585   ETP1_YEAST RING finger protein ETP1 OS=Saccha...260.9     36.2     42     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008139; F:nuclear localization sequence binding; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045471; P:response to ethanol; IMP:SGD.
313Q9LSW9    375   ATL16_ARATH RING-H2 finger protein ATL16 OS=A...550.92     35.8     25     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
314Q23985    738   DTX_DROME Protein deltex OS=Drosophila melano...710.92     36.2     32     46GO:0005829; C:cytosol; TAS:Reactome.
GO:0005112; F:Notch binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045746; P:negative regulation of Notch signaling pathway; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; IGI:FlyBase.::GO:0045747; P:positive regulation of Notch signaling pathway; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IMP:UniProtKB.
315Q9C919    178   ATL19_ARATH Putative RING-H2 finger protein A...330.93     35     39     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
316P0CH01    372   AT21A_ARATH Putative RING-H2 finger protein A...570.97     35.8     30     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
317P87237    821   YC0C_SCHPO Uncharacterized RING finger protei...530.97     36.2     28     49
GO:0008270; F:zinc ion binding; IEA:InterPro.
318Q940Q4    472   ATL13_ARATH RING-H2 finger protein ATL13 OS=A...531     35.8     30     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0080167; P:response to karrikin; IEP:TAIR.
319Q8LC69    185   ATL8_ARATH RING-H2 finger protein ATL8 OS=Ara...241.1     34.7     46     63GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
320Q95K04    376   RN133_MACFA E3 ubiquitin-protein ligase RNF13...651.2     35.4     29     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
321Q7ZUK0    364   RN146_DANRE E3 ubiquitin-protein ligase rnf14...581.2     35.4     31     43GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
322Q94BY6    226   ATL75_ARATH RING-H2 finger protein ATL75 OS=A...531.3     35     28     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
323Q06554    1556   IRC20_YEAST Uncharacterized ATP-dependent hel...651.3     35.8     28     46GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045003; P:double-strand break repair via synthesis-dependent strand annealing; IMP:SGD.
324Q9CR50    261   ZN363_MOUSE RING finger and CHY zinc finger d...711.3     35     30     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
325O64762    302   ATL38_ARATH RING-H2 finger protein ATL38 OS=A...321.3     35     34     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
326O80927    235   ATL33_ARATH RING-H2 finger protein ATL33 OS=A...271.3     35     41     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
327Q5UQ40    1297   UBC4_MIMIV Probable bifunctional E2/E3 enzyme...291.4     35.8     31     55GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
328Q96PM5    261   ZN363_HUMAN RING finger and CHY zinc finger d...711.4     35     30     42GO:0005737; C:cytoplasm; IDA:HGNC.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
329Q9ZV53    423   ATL49_ARATH Putative RING-H2 finger protein A...241.5     35     42     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
330Q8WVZ7    376   RN133_HUMAN E3 ubiquitin-protein ligase RNF13...671.5     35     28     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
331Q71FD5    238   ZNRF2_MOUSE E3 ubiquitin-protein ligase ZNRF2...551.5     34.7     31     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
records
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